BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
21 results:

  • 1. Inhibition of PAK1 generates an ameliorative effect on MPLW515L mouse model of myeloproliferative neoplasms by regulating the differentiation and survival of megakaryocytes.
    Fu C; Hu X; Wang S; Yu X; Zhang Q; Zhang L; Qi K; Li Z; Xu K
    Exp Hematol; 2023 Nov; 127():59-69.e2. PubMed ID: 37741606
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. 7,8-Dihydroxy-3-(4'-hydroxyphenyl)coumarin inhibits invasion and migration of osteosarcoma cells.
    Sugiyama Y; Nakamura S; Tokuda Y; Nakano M; Hattori Y; Nishiguchi H; Toda Y; Hosogi S; Yamashita M; Tashiro K; Ashihara E
    Biochem Biophys Res Commun; 2023 Jan; 638():200-209. PubMed ID: 36462494
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Nuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone.
    Kimura A; Toda Y; Matsumoto Y; Yamamoto H; Yahiro K; Shimada E; Kanahori M; Oyama R; Fukushima S; Nakagawa M; Setsu N; Endo M; Fujiwara T; Matsunobu T; Oda Y; Nakashima Y
    Sci Rep; 2022 Aug; 12(1):13438. PubMed ID: 35927428
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. CircSRSF4 Enhances Proliferation, Invasion, and Migration to Promote the Progression of Osteosarcoma via rac1.
    Sun X; Zhao X; Xu S; Zhou Y; Jia Z; Li Y
    Int J Mol Sci; 2022 May; 23(11):. PubMed ID: 35682879
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through rac1 and RhoA.
    Wang J; Yuan L; Xu X; Zhang Z; Ma Y; Hong L; Ma J
    Cell Death Dis; 2021 Dec; 12(12):1148. PubMed ID: 34893584
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Tumour-derived exosomal lncRNA-SOX2OT promotes bone metastasis of non-small cell lung cancer by targeting the miRNA-194-5p/rac1 signalling axis in osteoclasts.
    Ni J; Zhang X; Li J; Zheng Z; Zhang J; Zhao W; Liu L
    Cell Death Dis; 2021 Jul; 12(7):662. PubMed ID: 34215717
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inhibitory effect of cathepsin K inhibitor (ODN-MK-0822) on invasion, migration and adhesion of human breast cancer cells in vitro.
    Vashum Y; Premsingh R; Kottaiswamy A; Soma M; Padmanaban A; Kalaiselvan P; Samuel S
    Mol Biol Rep; 2021 Jan; 48(1):105-116. PubMed ID: 33294960
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1.
    Zhuang X; Zhang H; Li X; Li X; Cong M; Peng F; Yu J; Zhang X; Yang Q; Hu G
    Nat Cell Biol; 2017 Oct; 19(10):1274-1285. PubMed ID: 28892080
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Transforming growth factor β induces bone marrow mesenchymal stem cell migration via noncanonical signals and N-cadherin.
    Dubon MJ; Yu J; Choi S; Park KS
    J Cell Physiol; 2018 Jan; 233(1):201-213. PubMed ID: 28213973
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. CD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/rac1 signaling.
    Manara MC; Terracciano M; Mancarella C; Sciandra M; Guerzoni C; Pasello M; Grilli A; Zini N; Picci P; Colombo MP; Morrione A; Scotlandi K
    Oncotarget; 2016 Nov; 7(48):79925-79942. PubMed ID: 27835596
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Aldo-keto reductase 1C1 induced by interleukin-1β mediates the invasive potential and drug resistance of metastatic bladder cancer cells.
    Matsumoto R; Tsuda M; Yoshida K; Tanino M; Kimura T; Nishihara H; Abe T; Shinohara N; Nonomura K; Tanaka S
    Sci Rep; 2016 Oct; 6():34625. PubMed ID: 27698389
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2.
    Capala ME; Maat H; Bonardi F; van den Boom V; Kuipers J; Vellenga E; Giepmans BN; Schuringa JJ
    PLoS One; 2015; 10(5):e0128585. PubMed ID: 26016997
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Attenuation of malignant phenotypes of breast cancer cells through eIF2α-mediated downregulation of rac1 signaling.
    Hamamura K; Minami K; Tanjung N; Wan Q; Koizumi M; Matsuura N; Na S; Yokota H
    Int J Oncol; 2014 Jun; 44(6):1980-8. PubMed ID: 24691491
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells.
    Park EH; Kim S; Jo JY; Kim SJ; Hwang Y; Kim JM; Song SY; Lee DK; Koh SS
    Carcinogenesis; 2013 Mar; 34(3):694-702. PubMed ID: 23222813
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Vasodilator-stimulated phosphoprotein regulates osteosarcoma cell migration.
    Wu G; Wei L; Yu A; Zhang M; Qi B; Su K; Hu X; Wang J
    Oncol Rep; 2011 Dec; 26(6):1609-15. PubMed ID: 21874265
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Individual and combined soy isoflavones exert differential effects on metastatic cancer progression.
    Martínez-Montemayor MM; Otero-Franqui E; Martinez J; De La Mota-Peynado A; Cubano LA; Dharmawardhane S
    Clin Exp Metastasis; 2010 Oct; 27(7):465-80. PubMed ID: 20517637
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Suppressive effects of statins on acute promyelocytic leukemia cells.
    Sassano A; Katsoulidis E; Antico G; Altman JK; Redig AJ; Minucci S; Tallman MS; Platanias LC
    Cancer Res; 2007 May; 67(9):4524-32. PubMed ID: 17483369
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A modified low-dose regimen of mitoxantrone and prednisolone in patients with androgen-independent prostate cancer.
    Sheen WC; Chen JS; Wang HM; Yang TS; Liaw CC; Lin YC
    Jpn J Clin Oncol; 2004 Jun; 34(6):337-41. PubMed ID: 15333686
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Prospective randomized Phase II trial of pegylated doxorubicin in the management of symptomatic hormone-refractory prostate carcinoma.
    Heidenreich A; Sommer F; Ohlmann CH; Schrader AJ; Olbert P; Goecke J; Engelmann UH
    Cancer; 2004 Sep; 101(5):948-56. PubMed ID: 15329902
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition.
    Chaplet M; Detry C; Deroanne C; Fisher LW; Castronovo V; Bellahcéne A
    Biochem J; 2004 Dec; 384(Pt 3):591-8. PubMed ID: 15324309
    [TBL] [Abstract] [Full Text] [Related]  


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