BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND SMAD3, JV15-2, 4088, ENSG00000166949, P84022, Smad3, MADH3, HsT17436, Smad 3, DKFZp686J10186, HSPC193, DKFZP586N0721, MGC60396 AND Treatment
25 results:

  • 1. (E)-SIS3 suppressed osteosarcoma progression via promoting cell apoptosis, arresting cell cycle, and regulating the tumor immune microenvironment.
    Huang Z; Zhang C; Zhu K; Hu J; Xu E; Ma X; Wang Y; Zhu Y; Zhu J
    Drug Dev Res; 2023 Dec; 84(8):1751-1763. PubMed ID: 37784254
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The mechanism of VCP-mediated metastasis of osteosarcoma based on cell autophagy and the EMT pathway.
    Li AA; Zhang Y; Li F; Zhou Y; Liu ZL; Long XH
    Clin Transl Oncol; 2023 Mar; 25(3):653-661. PubMed ID: 36284060
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Uncarboxylated osteocalcin promotes proliferation and metastasis of MDA-MB-231 cells through TGF-β/smad3 signaling pathway.
    Xu J; Ma L; Wang D; Yang J
    BMC Mol Cell Biol; 2022 Apr; 23(1):18. PubMed ID: 35413833
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Inhibition of proinflammatory signaling impairs fibrosis of bone marrow mesenchymal stromal cells in myeloproliferative neoplasms.
    Vukotić M; Kapor S; Dragojević T; Đikić D; Mitrović Ajtić O; Diklić M; Subotički T; Živković E; Beleslin Čokić B; Vojvodić A; Santibáñez JF; Gotić M; Čokić VP
    Exp Mol Med; 2022 Mar; 54(3):273-284. PubMed ID: 35288649
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. TGF‑β inhibitor RepSox suppresses osteosarcoma via the JNK/smad3 signaling pathway.
    He D; Gao J; Zheng L; Liu S; Ye L; Lai H; Pan B; Pan W; Lou C; Chen Z; Fan S
    Int J Oncol; 2021 Nov; 59(5):. PubMed ID: 34533199
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Reactivation of BMP signaling by suboptimal concentrations of MEK inhibitor and FK506 reduces organ-specific breast cancer metastasis.
    Ren J; Wang Y; Ware T; Iaria J; Ten Dijke P; Zhu HJ
    Cancer Lett; 2020 Nov; 493():41-54. PubMed ID: 32768522
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. 20(S)-ginsenoside Rh2 as agent for the treatment of LMN-CRC via regulating epithelial-mesenchymal transition.
    Yuan Y; Wang J; Xu M; Zhang Y; Wang Z; Liang L; Sun P
    Biosci Rep; 2020 Mar; 40(3):. PubMed ID: 32141497
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. p130Cas induces bone invasion by oral squamous cell carcinoma by regulating tumor epithelial-mesenchymal transition and cell proliferation.
    Yaginuma T; Gao J; Nagata K; Muroya R; Fei H; Nagano H; Chishaki S; Matsubara T; Kokabu S; Matsuo K; Kiyoshima T; Yoshioka I; Jimi E
    Carcinogenesis; 2020 Aug; 41(8):1038-1048. PubMed ID: 31996896
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Chromatin remodeling factor BAZ1A regulates cellular senescence in both cancer and normal cells.
    Li X; Ding D; Yao J; Zhou B; Shen T; Qi Y; Ni T; Wei G
    Life Sci; 2019 Jul; 229():225-232. PubMed ID: 31085244
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. ING5 is a Potential Target for Osteosarcoma Therapy.
    Zhang X; Xu ZH; Xie H; Sun YW; Liu J; Zhao YB
    Technol Cancer Res Treat; 2018 Jan; 17():1533033818762680. PubMed ID: 29528777
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells.
    Shinohara N; Maeda S; Yahiro Y; Sakuma D; Matsuyama K; Imamura K; Kawamura I; Setoguchi T; Ishidou Y; Nagano S; Komiya S
    Sci Rep; 2017 Oct; 7(1):13494. PubMed ID: 29044189
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
    Cheng L; Ge M; Lan Z; Ma Z; Chi W; Kuang W; Sun K; Zhao X; Liu Y; Feng Y; Huang Y; Luo M; Li L; Zhang B; Hu X; Xu L; Liu X; Huo Y; Deng H; Yang J; Xi Q; Zhang Y; Siegenthaler JA; Chen L
    Arch Toxicol; 2018 Jan; 92(1):469-485. PubMed ID: 28871336
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Overexpression of miR-422a inhibits cell proliferation and invasion, and enhances chemosensitivity in osteosarcoma cells.
    Liu M; Xiusheng H; Xiao X; Wang Y
    Oncol Rep; 2016 Dec; 36(6):3371-3378. PubMed ID: 27779704
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases.
    Lamora A; Mullard M; Amiaud J; Brion R; Heymann D; Redini F; Verrecchia F
    Oncotarget; 2015 Jun; 6(16):14413-27. PubMed ID: 26015407
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. MicroRNA-153 inhibits osteosarcoma cells proliferation and invasion by targeting TGF-β2.
    Niu G; Li B; Sun L; An C
    PLoS One; 2015; 10(3):e0119225. PubMed ID: 25793604
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The BMP signaling pathway leads to enhanced proliferation in serous ovarian cancer-A potential therapeutic target.
    Peng J; Yoshioka Y; Mandai M; Matsumura N; Baba T; Yamaguchi K; Hamanishi J; Kharma B; Murakami R; Abiko K; Murphy SK; Konishi I
    Mol Carcinog; 2016 Apr; 55(4):335-45. PubMed ID: 25663289
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Overexpression of smad7 blocks primary tumor growth and lung metastasis development in osteosarcoma.
    Lamora A; Talbot J; Bougras G; Amiaud J; Leduc M; Chesneau J; Taurelle J; Stresing V; Le Deley MC; Heymann MF; Heymann D; Redini F; Verrecchia F
    Clin Cancer Res; 2014 Oct; 20(19):5097-112. PubMed ID: 25107916
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Transcriptional activation by NFκB increases perlecan/HSPG2 expression in the desmoplastic prostate tumor microenvironment.
    Warren CR; Grindel BJ; Francis L; Carson DD; Farach-Carson MC
    J Cell Biochem; 2014 Jul; 115(7):1322-33. PubMed ID: 24700612
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas.
    Kretschmer C; Conradi A; Kemmner W; Sterner-Kock A
    Cell Oncol (Dordr); 2011 Oct; 34(5):419-34. PubMed ID: 21468687
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases.
    Mohammad KS; Javelaud D; Fournier PG; Niewolna M; McKenna CR; Peng XH; Duong V; Dunn LK; Mauviel A; Guise TA
    Cancer Res; 2011 Jan; 71(1):175-84. PubMed ID: 21084275
    [TBL] [Abstract] [Full Text] [Related]  


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