BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND SMAD4, JIP, Q13485, 4089, ENSG00000141646, MADH4, DPC4 AND Prognosis
12 results:

  • 1. Loss of tumor-derived smad4 enhances primary tumor growth but not metastasis following BMP4 signalling.
    Chi LH; Redfern AD; Roslan S; Street IP; Burrows AD; Anderson RL
    Cell Commun Signal; 2024 Apr; 22(1):248. PubMed ID: 38689334
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling.
    Hu X; Zhang L; Li Y; Ma X; Dai W; Gao X; Rao X; Fu G; Wang R; Pan M; Guo Q; Xu X; Zhou Y; Gao J; Zhang Z; Cai S; Peng J; Hua G
    EBioMedicine; 2020 Jun; 56():102800. PubMed ID: 32512510
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Growth-Inhibitory Activity of bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression.
    Dalmo E; Johansson P; Niklasson M; Gustavsson I; Nelander S; Westermark B
    Mol Cancer Res; 2020 Jul; 18(7):981-991. PubMed ID: 32234828
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.
    Yan HHN; Siu HC; Ho SL; Yue SSK; Gao Y; Tsui WY; Chan D; Chan AS; Wong JWH; Man AHY; Lee BCH; Chan ASY; Chan AKW; Hui HS; Cheung AKL; Law WL; Lo OSH; Yuen ST; Clevers H; Leung SY
    Gut; 2020 Dec; 69(12):2165-2179. PubMed ID: 32217638
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Bidirectional tumor/stroma crosstalk promotes metastasis in mesenchymal colorectal cancer.
    Ouahoud S; Voorneveld PW; van der Burg LRA; de Jonge-Muller ESM; Schoonderwoerd MJA; Paauwe M; de Vos T; de Wit S; van Pelt GW; Mesker WE; Hawinkels LJAC; Hardwick JCH
    Oncogene; 2020 Mar; 39(12):2453-2466. PubMed ID: 31974473
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Long Noncoding RNA SNHG7 Promotes the Tumor Growth and Epithelial-to-Mesenchymal Transition via Regulation of miR-34a Signals in Osteosarcoma.
    Deng Y; Zhao F; Zhang Z; Sun F; Wang M
    Cancer Biother Radiopharm; 2018 Nov; 33(9):365-372. PubMed ID: 29989838
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Overexpression of the BMP4/SMAD signaling pathway in skull base chordomas is associated with poor prognosis.
    Feng Y; Zhang Q; Wang Z; Yan B; Wei W; Li P
    Int J Clin Exp Pathol; 2015; 8(7):8268-75. PubMed ID: 26339396
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications.
    Churi CR; Shroff R; Wang Y; Rashid A; Kang HC; Weatherly J; Zuo M; Zinner R; Hong D; Meric-Bernstam F; Janku F; Crane CH; Mishra L; Vauthey JN; Wolff RA; Mills G; Javle M
    PLoS One; 2014; 9(12):e115383. PubMed ID: 25536104
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.
    Wong CC; Tse AP; Huang YP; Zhu YT; Chiu DK; Lai RK; Au SL; Kai AK; Lee JM; Wei LL; Tsang FH; Lo RC; Shi J; Zheng YP; Wong CM; Ng IO
    Hepatology; 2014 Nov; 60(5):1645-58. PubMed ID: 25048396
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Loss of smad4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
    Voorneveld PW; Kodach LL; Jacobs RJ; Liv N; Zonnevylle AC; Hoogenboom JP; Biemond I; Verspaget HW; Hommes DW; de Rooij K; van Noesel CJ; Morreau H; van Wezel T; Offerhaus GJ; van den Brink GR; Peppelenbosch MP; Ten Dijke P; Hardwick JC
    Gastroenterology; 2014 Jul; 147(1):196-208.e13. PubMed ID: 24704720
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis.
    Voorneveld PW; Stache V; Jacobs RJ; Smolders E; Sitters AI; Liesker A; Korkmaz KS; Lam SM; De Miranda NF; Morreau H; Kodach LL; Hardwick JC
    Br J Cancer; 2013 Oct; 109(7):1805-12. PubMed ID: 23969729
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The activation of MEK/ERK signaling pathway by bone morphogenetic protein 4 to increase hepatocellular carcinoma cell proliferation and migration.
    Chiu CY; Kuo KK; Kuo TL; Lee KT; Cheng KH
    Mol Cancer Res; 2012 Mar; 10(3):415-27. PubMed ID: 22241220
    [TBL] [Abstract] [Full Text] [Related]  


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