BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND SMAD4, JIP, Q13485, 4089, ENSG00000141646, MADH4, DPC4 AND Treatment
38 results:

  • 1. Executive summary of the 14th HHT international scientific conference.
    Ola R; Hessels J; Hammill A; Friday C; Clancy M; Al-Samkari H; Meadows S; Iyer V; Akhurst R
    Angiogenesis; 2023 Aug; 26(Suppl 1):27-37. PubMed ID: 37695357
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Selective targeting BMP2 and 4 in smad4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models.
    Li S; Hoefnagel SJM; Read M; Meijer S; van Berge Henegouwen MI; Gisbertz SS; Bonora E; Liu DSH; Phillips WA; Calpe S; Correia ACP; Sancho-Serra MDC; Mattioli S; Krishnadath KK;
    Cell Oncol (Dordr); 2022 Aug; 45(4):639-658. PubMed ID: 35902550
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche.
    Yao JC; Oetjen KA; Wang T; Xu H; Abou-Ezzi G; Krambs JR; Uttarwar S; Duncavage EJ; Link DC
    J Clin Invest; 2022 Jun; 132(11):. PubMed ID: 35439167
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: Results from the CONKO-005 trial.
    Hoyer K; Hablesreiter R; Inoue Y; Yoshida K; Briest F; Christen F; Kakiuchi N; Yoshizato T; Shiozawa Y; Shiraishi Y; Striefler JK; Bischoff S; Lohneis P; Putter H; Blau O; Keilholz U; Bullinger L; Pelzer U; Hummel M; Riess H; Ogawa S; Sinn M; Damm F
    EBioMedicine; 2021 Apr; 66():103327. PubMed ID: 33862582
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Arginine methylation of R81 in Smad6 confines BMP-induced Smad1 signaling.
    Wu J; Chen X; Sehgal P; Zhang T; Jackson-Weaver O; Gou Y; Bautch V; Frenkel B; Sun H; Xu J
    J Biol Chem; 2021; 296():100496. PubMed ID: 33667543
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Growth-Inhibitory Activity of bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression.
    Dalmo E; Johansson P; Niklasson M; Gustavsson I; Nelander S; Westermark B
    Mol Cancer Res; 2020 Jul; 18(7):981-991. PubMed ID: 32234828
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling.
    Boutanquoi PM; Burgy O; Beltramo G; Bellaye PS; Dondaine L; Marcion G; Pommerolle L; Vadel A; Spanjaard M; Demidov O; Mailleux A; Crestani B; Kolb M; Garrido C; Goirand F; Bonniaud P
    Eur Respir J; 2020 Jun; 55(6):. PubMed ID: 32184320
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. PARP Inhibition Enhances Radiotherapy of smad4-Deficient Human Head and Neck Squamous Cell Carcinomas in Experimental Models.
    Hernandez AL; Young CD; Bian L; Weigel K; Nolan K; Frederick B; Han G; He G; Devon Trahan G; Rudolph MC; Jones KL; Oweida AJ; Karam SD; Raben D; Wang XJ
    Clin Cancer Res; 2020 Jun; 26(12):3058-3070. PubMed ID: 32139402
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate cancers.
    Moreira D; Adamus T; Zhao X; Su YL; Zhang Z; White SV; Swiderski P; Lu X; DePinho RA; Pal SK; Kortylewski M
    Clin Cancer Res; 2018 Dec; 24(23):5948-5962. PubMed ID: 30337279
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Epithelial smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated cancer.
    Means AL; Freeman TJ; Zhu J; Woodbury LG; Marincola-Smith P; Wu C; Meyer AR; Weaver CJ; Padmanabhan C; An H; Zi J; Wessinger BC; Chaturvedi R; Brown TD; Deane NG; Coffey RJ; Wilson KT; Smith JJ; Sawyers CL; Goldenring JR; Novitskiy SV; Washington MK; Shi C; Beauchamp RD
    Cell Mol Gastroenterol Hepatol; 2018; 6(3):257-276. PubMed ID: 30109253
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. ING5 is a Potential Target for Osteosarcoma Therapy.
    Zhang X; Xu ZH; Xie H; Sun YW; Liu J; Zhao YB
    Technol Cancer Res Treat; 2018 Jan; 17():1533033818762680. PubMed ID: 29528777
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling.
    Zhao HJ; Klausen C; Li Y; Zhu H; Wang YL; Leung PCK
    Cell Death Dis; 2018 Feb; 9(2):174. PubMed ID: 29416020
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Comprehensive molecular profiling of advanced/metastatic olfactory neuroblastomas.
    Topcagic J; Feldman R; Ghazalpour A; Swensen J; Gatalica Z; Vranic S
    PLoS One; 2018; 13(1):e0191244. PubMed ID: 29324814
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Genetic Heterogeneity in Therapy-Naïve Synchronous Primary Breast cancers and Their Metastases.
    Ng CKY; Bidard FC; Piscuoglio S; Geyer FC; Lim RS; de Bruijn I; Shen R; Pareja F; Berman SH; Wang L; Pierga JY; Vincent-Salomon A; Viale A; Norton L; Sigal B; Weigelt B; Cottu P; Reis-Filho JS
    Clin Cancer Res; 2017 Aug; 23(15):4402-4415. PubMed ID: 28351929
    [No Abstract]    [Full Text] [Related]  

  • 15. Abnormal Uterine Bleeding Is Associated With Increased BMP7 Expression in Human Endometrium.
    Richards EG; El-Nashar SA; Schoolmeester JK; Keeney GL; Mariani A; Hopkins MR; Dowdy SC; Daftary GS; Famuyide AO
    Reprod Sci; 2017 May; 24(5):671-681. PubMed ID: 28142396
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling.
    Tseng JC; Lin CY; Su LC; Fu HH; Yang SD; Chuu CP
    Oncotarget; 2016 Jun; 7(25):38010-38024. PubMed ID: 27191743
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Curcumin inhibits the proliferation and invasion of human osteosarcoma cell line MG-63 by regulating miR-138.
    Yu D; An F; He X; Cao X
    Int J Clin Exp Pathol; 2015; 8(11):14946-52. PubMed ID: 26823826
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology.
    Tate CM; Mc Entire J; Pallini R; Vakana E; Wyss L; Blosser W; Ricci-Vitiani L; D'Alessandris QG; Morgante L; Giannetti S; Larocca LM; Todaro M; Benfante A; Colorito ML; Stassi G; De Maria R; Rowlinson S; Stancato L
    PLoS One; 2015; 10(4):e0125697. PubMed ID: 25919028
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. smad4 Decreases the Population of Pancreatic cancer-Initiating Cells through Transcriptional Repression of ALDH1A1.
    Hoshino Y; Nishida J; Katsuno Y; Koinuma D; Aoki T; Kokudo N; Miyazono K; Ehata S
    Am J Pathol; 2015 May; 185(5):1457-70. PubMed ID: 25769430
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.
    Chubb D; Broderick P; Frampton M; Kinnersley B; Sherborne A; Penegar S; Lloyd A; Ma YP; Dobbins SE; Houlston RS
    J Clin Oncol; 2015 Feb; 33(5):426-32. PubMed ID: 25559809
    [TBL] [Abstract] [Full Text] [Related]  


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