BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND TGFBR2, AAT3, 7048, ENSG00000163513, P37173, TGFbeta-RII, RIIC, TAAD2, FAA3, TGFR-2, MFS2, HNPCC6
28 results:

  • 1. Beauvericin suppresses the proliferation and pulmonary metastasis of osteosarcoma by selectively inhibiting tgfbr2 pathway.
    Ye G; Jiao Y; Deng L; Cheng M; Wang S; Zhang J; Ouyang J; Li Y; He Y; Tu Z; Wang Z; Song X; Wang C; Qi Q; Zhang D; Wang L; Huang M; Ye W; Chen M
    Int J Biol Sci; 2023; 19(14):4376-4392. PubMed ID: 37781043
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression.
    Bailey P; Ridgway RA; Cammareri P; Treanor-Taylor M; Bailey UM; Schoenherr C; Bone M; Schreyer D; Purdie K; Thomson J; Rickaby W; Jackstadt R; Campbell AD; Dimonitsas E; Stratigos AJ; Arron ST; Wang J; Blyth K; Proby CM; Harwood CA; Sansom OJ; Leigh IM; Inman GJ
    Nat Commun; 2023 Aug; 14(1):5211. PubMed ID: 37626054
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Enzalutamide-induced and PTH1R-mediated tgfbr2 degradation in osteoblasts confers resistance in prostate cancer bone metastases.
    Su S; Cao J; Meng X; Liu R; Vander Ark A; Woodford E; Zhang R; Stiver I; Zhang X; Madaj ZB; Bowman MJ; Wu Y; Xu HE; Chen B; Yu H; Li X
    Cancer Lett; 2022 Jan; 525():170-178. PubMed ID: 34752846
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Abnormal Expression and Prognostic Significance of bone Morphogenetic Proteins and Their Receptors in Lung Adenocarcinoma.
    Xu Z; Chen C
    Biomed Res Int; 2021; 2021():6663990. PubMed ID: 34036102
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Imbalance of TGF-β1/BMP-7 pathways induced by M2-polarized macrophages promotes hepatocellular carcinoma aggressiveness.
    Ning J; Ye Y; Bu D; Zhao G; Song T; Liu P; Yu W; Wang H; Li H; Ren X; Ying G; Zhao Y; Yu J
    Mol Ther; 2021 Jun; 29(6):2067-2087. PubMed ID: 33601054
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The downregulation of IGFBP3 by TGF-β signaling in oral cancer contributes to the osteoclast differentiation.
    Park J; Jung MJ; Chung WY
    Biochem Biophys Res Commun; 2021 Jan; 534():381-386. PubMed ID: 33256984
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Transforming growth factor β-mediated micromechanics modulates disease progression in primary myelofibrosis.
    Teodorescu P; Pasca S; Jurj A; Gafencu G; Joelsson JP; Selicean S; Moldovan C; Munteanu R; Onaciu A; Tigu AB; Buse M; Zimta AA; Stiufiuc R; Petrushev B; Desmirean M; Dima D; Vlad C; Bergthorsson JT; Berce C; Ciurea S; Ghiaur G; Tomuleasa C
    J Cell Mol Med; 2020 Oct; 24(19):11100-11110. PubMed ID: 32889753
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling.
    Bae JS; Jeon Y; Kim SM; Jang JY; Park MK; Kim IH; Hwang DS; Lim DS; Lee H
    Cell Death Dis; 2018 Oct; 9(11):1083. PubMed ID: 30349003
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A Pan-cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.
    Korkut A; Zaidi S; Kanchi RS; Rao S; Gough NR; Schultz A; Li X; Lorenzi PL; Berger AC; Robertson G; Kwong LN; Datto M; Roszik J; Ling S; Ravikumar V; Manyam G; Rao A; Shelley S; Liu Y; Ju Z; Hansel D; de Velasco G; Pennathur A; Andersen JB; O'Rourke CJ; Ohshiro K; Jogunoori W; Nguyen BN; Li S; Osmanbeyoglu HU; Ajani JA; Mani SA; Houseman A; Wiznerowicz M; Chen J; Gu S; Ma W; Zhang J; Tong P; Cherniack AD; Deng C; Resar L; ; Weinstein JN; Mishra L; Akbani R
    Cell Syst; 2018 Oct; 7(4):422-437.e7. PubMed ID: 30268436
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs.
    Pellatt AJ; Mullany LE; Herrick JS; Sakoda LC; Wolff RK; Samowitz WS; Slattery ML
    J Transl Med; 2018 Jul; 16(1):191. PubMed ID: 29986714
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. BMP7 Signaling in
    Eikesdal HP; Becker LM; Teng Y; Kizu A; Carstens JL; Kanasaki K; Sugimoto H; LeBleu VS; Kalluri R
    Mol Cancer Res; 2018 Oct; 16(10):1568-1578. PubMed ID: 29934328
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The tumor suppressive TGF-β/SMAD1/S1PR2 signaling axis is recurrently inactivated in diffuse large B-cell lymphoma.
    Stelling A; Hashwah H; Bertram K; Manz MG; Tzankov A; Müller A
    Blood; 2018 May; 131(20):2235-2246. PubMed ID: 29615404
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis.
    Meng X; Vander Ark A; Daft P; Woodford E; Wang J; Madaj Z; Li X
    Cancer Lett; 2018 Apr; 418():109-118. PubMed ID: 29337106
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis.
    Rodriguez Calleja L; Jacques C; Lamoureux F; Baud'huin M; Tellez Gabriel M; Quillard T; Sahay D; Perrot P; Amiaud J; Charrier C; Brion R; Lecanda F; Verrecchia F; Heymann D; Ellisen LW; Ory B
    Cancer Res; 2016 Jun; 76(11):3236-51. PubMed ID: 26988989
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ.
    Yan HH; Jiang J; Pang Y; Achyut BR; Lizardo M; Liang X; Hunter K; Khanna C; Hollander C; Yang L
    Cancer Res; 2015 Dec; 75(24):5283-98. PubMed ID: 26483204
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Myeloid-specific TGF-β signaling in bone promotes basic-FGF and breast cancer bone metastasis.
    Meng X; Vander Ark A; Lee P; Hostetter G; Bhowmick NA; Matrisian LM; Williams BO; Miranti CK; Li X
    Oncogene; 2016 May; 35(18):2370-8. PubMed ID: 26279296
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation.
    Pinheiro M; Pinto C; Peixoto A; Veiga I; Lopes P; Henrique R; Baldaia H; Carneiro F; Seruca R; Tomlinson I; Kovac M; Heinimann K; Teixeira MR
    Br J Cancer; 2015 Aug; 113(4):686-92. PubMed ID: 26247575
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Overexpression of Gremlin-1 in patients with Loeys-Dietz syndrome: implications on pathophysiology and early disease detection.
    Wellbrock J; Sheikhzadeh S; Oliveira-Ferrer L; Stamm H; Hillebrand M; Keyser B; Klokow M; Vohwinkel G; Bonk V; Otto B; Streichert T; Balabanov S; Hagel C; Rybczynski M; Bentzien F; Bokemeyer C; von Kodolitsch Y; Fiedler W
    PLoS One; 2014; 9(8):e104742. PubMed ID: 25116393
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. TGF-β signaling in myeloid cells is required for tumor metastasis.
    Pang Y; Gara SK; Achyut BR; Li Z; Yan HH; Day CP; Weiss JM; Trinchieri G; Morris JC; Yang L
    Cancer Discov; 2013 Aug; 3(8):936-51. PubMed ID: 23661553
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Modulation of the osteosarcoma expression phenotype by microRNAs.
    Namløs HM; Meza-Zepeda LA; Barøy T; Østensen IH; Kresse SH; Kuijjer ML; Serra M; Bürger H; Cleton-Jansen AM; Myklebost O
    PLoS One; 2012; 7(10):e48086. PubMed ID: 23133552
    [TBL] [Abstract] [Full Text] [Related]  


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