BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND uPA
131 results:

  • 1. Morin inhibits osteosarcoma migration and invasion by suppressing urokinase plasminogen activator through a signal transducer and an activator of transcription 3.
    Yang JS; Chou CH; Hsieh YH; Lu PW; Lin YC; Yang SF; Lu KH
    Environ Toxicol; 2024 Apr; 39(4):2024-2031. PubMed ID: 38093596
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Bisdemethoxycurcumin suppresses human osteosarcoma U‑2 OS cell migration and invasion via affecting the PI3K/Akt/NF‑κB, PI3K/Akt/GSK3β and MAPK signaling pathways
    Ma YS; Peng SF; Wu RS; Chueh FS; Huang WW; Chen PY; Kuo CL; Huang AC; Liao CL; Hsia TC
    Oncol Rep; 2022 Dec; 48(6):. PubMed ID: 36222295
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Prognostic significance of the urokinase plasminogen activator system in tissue and serum of dogs with appendicular osteosarcoma.
    Matsuyama A; Wood GA; Speare R; Schott CR; Mutsaers AJ
    PLoS One; 2022; 17(9):e0273811. PubMed ID: 36174075
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Cinnamaldehyde decreases the invasion and u-PA expression of osteosarcoma by down-regulating the FAK signalling pathway.
    Chu SC; Hsieh YS; Hsu LS; Lin CY; Lai YA; Chen PN
    Food Funct; 2022 Jun; 13(12):6574-6582. PubMed ID: 35678522
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Dihydromyricetin suppresses cell metastasis in human osteosarcoma through SP-1- and NF-κB-modulated urokinase plasminogen activator inhibition.
    Chou CH; Lu KH; Yang JS; Hsieh YH; Lin CW; Yang SF
    Phytomedicine; 2021 Sep; 90():153642. PubMed ID: 34265701
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Transforming growth factor-β-regulated fractalkine as a marker of erosive bone invasion in oral squamous cell carcinoma.
    Son SH; Park J; Jung MJ; Lee SK; Kim H; Kim KR; Park KK; Chung WY
    Eur J Oral Sci; 2021 Feb; 129(1):e12750. PubMed ID: 33503283
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Curcumin Analogue L48H37 Suppresses Human Osteosarcoma U2OS and MG-63 Cells' Migration and Invasion in Culture by Inhibition of upa via the JAK/STAT Signaling Pathway.
    Lu KH; Wu HH; Lin RC; Lin YC; Lu PW; Yang SF; Yang JS
    Molecules; 2020 Dec; 26(1):. PubMed ID: 33374783
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Inhibitory Effects of a Reengineered Anthrax Toxin on Canine and Human Osteosarcoma Cells.
    Mackowiak da Fonseca J; Mackowiak da Fonseca II; Nagamine MK; Massoco CO; Nishiya AT; Ward JM; Liu S; Leppla SH; Bugge TH; Dagli MLZ
    Toxins (Basel); 2020 Sep; 12(10):. PubMed ID: 32987941
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. HO-1 Interactors Involved in the Colonization of the bone Niche: Role of ANXA2 in Prostate cancer Progression.
    Anselmino N; Bizzotto J; Sanchis P; Lage-Vickers S; Ortiz E; Valacco P; Paez A; Labanca E; Meiss R; Navone N; Cotignola J; Vazquez E; Gueron G
    Biomolecules; 2020 Mar; 10(3):. PubMed ID: 32197509
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The plasminogen activator inhibitor-1 paradox in cancer: a mechanistic understanding.
    Kubala MH; DeClerck YA
    Cancer Metastasis Rev; 2019 Sep; 38(3):483-492. PubMed ID: 31734763
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Impact of upa/PAI-1 and disseminated cytokeratin-positive cells in breast cancer.
    Märkl B; Kazik M; Harbeck N; Jakubowicz E; Hoffmann R; Jung T; Steinfeld D; Schenkirsch G; Schlimok G; Oruzio D
    BMC Cancer; 2019 Jul; 19(1):692. PubMed ID: 31307406
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Fisetin Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion
    Chen JK; Peng SF; Lai KC; Liu HC; Huang YP; Lin CC; Huang AC; Chueh FS; Chung JG
    In Vivo; 2019; 33(3):801-810. PubMed ID: 31028200
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Lupeol suppresses migration and invasion
    Hsu MJ; Peng SF; Chueh FS; Tsai CH; Tsai FJ; Huang CY; Tang CH; Yang JS; Hsu YM; Huang WW; Chung JG
    Biosci Biotechnol Biochem; 2019 Sep; 83(9):1729-1739. PubMed ID: 31010399
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Repeated two cycles of ulipristal acetate treatment improve the quality of life in premenopausal women with heavy menstrual bleeding dependent on uterine myomas, without impairment of bone health.
    Neri M; Pilloni M; Paoletti AM; Melis GB; Piras B; Ajossa S; Marotto MF; Corda V; Ronchi A; Giancane E; Vallerino V; Saba A; Zedda P; Orani MP; Cappai R; Coghe F; Mais V
    Gynecol Endocrinol; 2019 Sep; 35(9):756-761. PubMed ID: 30822182
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in cancer.
    Kubala MH; Punj V; Placencio-Hickok VR; Fang H; Fernandez GE; Sposto R; DeClerck YA
    Cell Rep; 2018 Nov; 25(8):2177-2191.e7. PubMed ID: 30463014
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Inflammation-driven colon neoplasmatogenesis in upa-deficient mice is associated with an increased expression of Runx transcriptional regulators.
    Afaloniati H; Karagiannis GS; Hardas A; Poutahidis T; Angelopoulou K
    Exp Cell Res; 2017 Dec; 361(2):257-264. PubMed ID: 29107070
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Mesenchymal stem cells differentially affect the invasion of distinct glioblastoma cell lines.
    Breznik B; Motaln H; Vittori M; Rotter A; Lah Turnšek T
    Oncotarget; 2017 Apr; 8(15):25482-25499. PubMed ID: 28424417
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. u-PAR expression in cancer associated fibroblast: new acquisitions in multiple myeloma progression.
    Ciavarella S; Laurenzana A; De Summa S; Pilato B; Chillà A; Lacalamita R; Minoia C; Margheri F; Iacobazzi A; Rana A; Merchionne F; Fibbi G; Del Rosso M; Guarini A; Tommasi S; Serratì S
    BMC Cancer; 2017 Mar; 17(1):215. PubMed ID: 28340565
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. 3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo.
    Lu KH; Chen PN; Hsieh YH; Lin CY; Cheng FY; Chiu PC; Chu SC; Hsieh YS
    Food Chem Toxicol; 2016 Nov; 97():177-186. PubMed ID: 27600294
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. CITED2 Modulates Breast cancer Metastatic Ability through Effects on IKKα.
    Jayaraman S; Doucet M; Lau WM; Kominsky SL
    Mol Cancer Res; 2016 Aug; 14(8):730-9. PubMed ID: 27216153
    [TBL] [Abstract] [Full Text] [Related]  


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