BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR-1, MXR1, UAQTL1
422 results:

  • 1. Impact of the thyroid hormone T3 and its nuclear receptor TRα1 on colon cancer stem cell phenotypes and response to chemotherapies.
    Giolito MV; Bodoirat S; La Rosa T; Reslinger M; Guardia GDA; Mourtada J; Claret L; Joung A; Galante PAF; Penalva LOF; Plateroti M
    Cell Death Dis; 2024 May; 15(5):306. PubMed ID: 38693105
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Experimental and Computational Methods to Assess Central Nervous System Penetration of Small Molecules.
    Gupta M; Feng J; Bhisetti G
    Molecules; 2024 Mar; 29(6):. PubMed ID: 38542901
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. abcg2 Expression as a Potential Survival Predictor in Human Gliomas.
    Raguž M; Tarle M; Müller D; Tomasović-Lončarić Č; Chudy H; Marinović T; Chudy D
    Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542090
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. abcg2a is the functional homolog of human abcg2 expressed at the zebrafish blood-brain barrier.
    Thomas JR; Frye WJE; Robey RW; Warner AC; Butcher D; Matta JL; Morgan TC; Edmondson EF; Salazar PB; Ambudkar SV; Gottesman MM
    Fluids Barriers CNS; 2024 Mar; 21(1):27. PubMed ID: 38491505
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier.
    Colón Ortiz R; Knerler S; Fridman LB; Mercado A; Price AS; Rosado-Franco JJ; Wilkins H; Flores BR; Orsburn BC; Williams DW
    Fluids Barriers CNS; 2024 Jan; 21(1):5. PubMed ID: 38200564
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Utilizing a Dual Human Transporter MDCKII-MDR1-bcrp Cell Line to Assess Efflux at the Blood brain Barrier.
    Colclough N; Alluri RV; Tucker JW; Gozalpour E; Li D; Du H; Li W; Harlfinger S; O'Neill DJ; Sproat GG; Chen K; Yan Y; McGinnity DF
    Drug Metab Dispos; 2024 Jan; 52(2):95-105. PubMed ID: 38071533
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. A phase II study of atezolizumab with bevacizumab, carboplatin, and paclitaxel for patients with EGFR-mutated NSCLC after TKI treatment failure (NEJ043 study).
    Watanabe S; Furuya N; Nakamura A; Shiihara J; Nakachi I; Tanaka H; Nakao M; Minato K; Seike M; Sasaki S; Kisohara A; Takeuchi S; Honda R; Takamura K; Kagamu H; Yoshimura K; Kobayashi K; Kikuchi T
    Eur J Cancer; 2024 Jan; 197():113469. PubMed ID: 38061214
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Altering distribution profile of palbociclib by its prodrugs.
    Järvinen J; Montaser AB; Adla SK; Leppänen J; Lehtonen M; Vellonen KS; Laitinen T; Jalkanen A; Elmquist WF; Timonen J; Huttunen KM; Rautio J
    Eur J Pharm Sci; 2024 Jan; 192():106637. PubMed ID: 37967656
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Acquired and intrinsic resistance to vemurafenib in BRAF
    Zhang P; Kuil LE; Buil LCM; Freriks S; Beijnen JH; van Tellingen O; de Gooijer MC
    FEBS Open Bio; 2024 Jan; 14(1):96-111. PubMed ID: 37953496
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Dissimilar Effect of P-Glycoprotein and Breast cancer Resistance Protein Inhibition on the Distribution of Erlotinib to the Retina and brain in Humans and Mice.
    Biali ME; Auvity S; Cisternino S; Smirnova M; Hacker M; Zeitlinger M; Mairinger S; Tournier N; Bauer M; Langer O
    Mol Pharm; 2023 Nov; 20(11):5877-5887. PubMed ID: 37883694
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Central Nervous System Distribution of Panobinostat in Preclinical Models to Guide Dosing for Pediatric brain Tumors.
    Zhang W; Oh JH; Zhang W; Rathi S; Larson JD; Wechsler-Reya RJ; Sirianni RW; Elmquist WF
    J Pharmacol Exp Ther; 2023 Dec; 387(3):315-327. PubMed ID: 37827699
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Pharmacokinetics of the KRAS
    Loos NHC; Retmana IA; Rijmers J; Wang Y; Gan C; Lebre MC; Sparidans RW; Beijnen JH; Schinkel AH
    Biomed Pharmacother; 2023 Oct; 166():115304. PubMed ID: 37586117
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Clinical Pharmacokinetics and Pharmacodynamics of the Next Generation Androgen Receptor Inhibitor-Darolutamide.
    Podgoršek E; Mehra N; van Oort IM; Somford DM; Boerrigter E; van Erp NP
    Clin Pharmacokinet; 2023 Aug; 62(8):1049-1061. PubMed ID: 37458966
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. LncRNA GAS5 Regulates Gemcitabine Resistance in Pancreatic Carcinoma by Targeting miRNA-21.
    Huang K; Yang G
    Ann Clin Lab Sci; 2023 Mar; 53(2):222-229. PubMed ID: 37094852
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Transporter Activity In Vivo.
    Zhang Y; Shipkova PA; Warrack BM; Nelson DM; Wang L; Huo R; Chen J; Panfen E; Chen XQ; Fancher RM; Ruan Q; Christopher LJ; Xue Y; Sinz M; Shen H
    Drug Metab Dispos; 2023 Jul; 51(7):851-861. PubMed ID: 37055191
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas.
    de Sousa GR; Salomão KB; Nagano LFP; Riemondy KA; Chagas PS; Veronez LC; Saggioro FP; Marie SKN; Yunes JA; Cardinalli IA; Brandalise SR; de Paula Queiroz RG; Scrideli CA; Donson AM; Foreman NK; Tone LG; Valera ET
    Cancer Gene Ther; 2023 Aug; 30(8):1105-1113. PubMed ID: 37041276
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Exploratory analysis of immunochemotherapy compared to chemotherapy after EGFR-TKI in non-small cell lung cancer patients with EGFR mutation: A multicenter retrospective study.
    Hata T; Sakaguchi C; Hirano K; Kobe H; Ishida M; Nakano T; Tachibana Y; Tamiya N; Shiotsu S; Takeda T; Yamada T; Yokoyama T; Tsuchiya M; Nagasaka Y
    Thorac Cancer; 2023 Apr; 14(11):1004-1011. PubMed ID: 36866788
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. cancer Stem Cell and Aggressiveness Traits Are Promoted by Stable Endothelin-Converting Enzyme-1c in Glioblastoma Cells.
    Niechi I; Erices JI; Carrillo-Beltrán D; Uribe-Ojeda A; Torres Á; Rocha JD; Uribe D; Toro MA; Villalobos-Nova K; Gaete-Ramírez B; Mingo G; Owen GI; Varas-Godoy M; Jara L; Aguayo F; Burzio VA; Quezada-Monrás C; Tapia JC
    Cells; 2023 Feb; 12(3):. PubMed ID: 36766848
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood-brain barrier.
    Lye P; Bloise E; Matthews SG
    Fluids Barriers CNS; 2023 Jan; 20(1):8. PubMed ID: 36721242
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Recent advances in the in vitro and in vivo methods to assess impact of P-glycoprotein and breast cancer resistance protein transporters in central nervous system drug disposition.
    Chatterjee S; Deshpande AA; Shen H
    Biopharm Drug Dispos; 2023 Feb; 44(1):7-25. PubMed ID: 36692150
    [TBL] [Abstract] [Full Text] [Related]  


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