Terms: = Brain cancer AND ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR-1, MXR1, UAQTL1 AND Treatment
150 results:
1. Impact of the thyroid hormone T3 and its nuclear receptor TRα1 on colon cancer stem cell phenotypes and response to chemotherapies.
Giolito MV; Bodoirat S; La Rosa T; Reslinger M; Guardia GDA; Mourtada J; Claret L; Joung A; Galante PAF; Penalva LOF; Plateroti M
Cell Death Dis; 2024 May; 15(5):306. PubMed ID: 38693105
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2. abcg2 Expression as a Potential Survival Predictor in Human Gliomas.
Raguž M; Tarle M; Müller D; Tomasović-Lončarić Č; Chudy H; Marinović T; Chudy D
Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542090
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3. Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier.
Colón Ortiz R; Knerler S; Fridman LB; Mercado A; Price AS; Rosado-Franco JJ; Wilkins H; Flores BR; Orsburn BC; Williams DW
Fluids Barriers CNS; 2024 Jan; 21(1):5. PubMed ID: 38200564
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4. A phase II study of atezolizumab with bevacizumab, carboplatin, and paclitaxel for patients with EGFR-mutated NSCLC after TKI treatment failure (NEJ043 study).
Watanabe S; Furuya N; Nakamura A; Shiihara J; Nakachi I; Tanaka H; Nakao M; Minato K; Seike M; Sasaki S; Kisohara A; Takeuchi S; Honda R; Takamura K; Kagamu H; Yoshimura K; Kobayashi K; Kikuchi T
Eur J Cancer; 2024 Jan; 197():113469. PubMed ID: 38061214
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5. Altering distribution profile of palbociclib by its prodrugs.
Järvinen J; Montaser AB; Adla SK; Leppänen J; Lehtonen M; Vellonen KS; Laitinen T; Jalkanen A; Elmquist WF; Timonen J; Huttunen KM; Rautio J
Eur J Pharm Sci; 2024 Jan; 192():106637. PubMed ID: 37967656
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6. Central Nervous System Distribution of Panobinostat in Preclinical Models to Guide Dosing for Pediatric brain Tumors.
Zhang W; Oh JH; Zhang W; Rathi S; Larson JD; Wechsler-Reya RJ; Sirianni RW; Elmquist WF
J Pharmacol Exp Ther; 2023 Dec; 387(3):315-327. PubMed ID: 37827699
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7. Clinical Pharmacokinetics and Pharmacodynamics of the Next Generation Androgen Receptor Inhibitor-Darolutamide.
Podgoršek E; Mehra N; van Oort IM; Somford DM; Boerrigter E; van Erp NP
Clin Pharmacokinet; 2023 Aug; 62(8):1049-1061. PubMed ID: 37458966
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8. Exploratory analysis of immunochemotherapy compared to chemotherapy after EGFR-TKI in non-small cell lung cancer patients with EGFR mutation: A multicenter retrospective study.
Hata T; Sakaguchi C; Hirano K; Kobe H; Ishida M; Nakano T; Tachibana Y; Tamiya N; Shiotsu S; Takeda T; Yamada T; Yokoyama T; Tsuchiya M; Nagasaka Y
Thorac Cancer; 2023 Apr; 14(11):1004-1011. PubMed ID: 36866788
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9. Reduction in abcg2 mRNA Expression in Human Immortalised brain Microvascular Endothelial Cells by Ferric Ammonium Citrate is Mediated by Reactive Oxygen Species and Activation of ERK1/2 Signalling.
Newman SA; Short JL; Nicolazzo JA
Pharm Res; 2023 Mar; 40(3):651-660. PubMed ID: 36539667
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10. Valproic Acid-Induced Upregulation of Multidrug Efflux Transporter abcg2/bcrp via PPAR
Kukal S; Bora S; Kanojia N; Singh P; Paul PR; Rawat C; Sagar S; Bhatraju NK; Grewal GK; Singh A; Kukreti S; Satyamoorthy K; Kukreti R
Mol Pharmacol; 2023 Mar; 103(3):145-157. PubMed ID: 36414374
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11. CRISPR/Cas9-induced knockout reveals the role of ABCB1 in the response to temozolomide, carmustine and lomustine in glioblastoma multiforme.
Radtke L; Majchrzak-Celińska A; Awortwe C; Vater I; Nagel I; Sebens S; Cascorbi I; Kaehler M
Pharmacol Res; 2022 Nov; 185():106510. PubMed ID: 36252775
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12. Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: Anchor point for innovative Alzheimer's disease therapeutics.
Namasivayam V; Stefan K; Gorecki L; Korabecny J; Soukup O; Jansson PJ; Pahnke J; Stefan SM
Int J Biol Macromol; 2022 Sep; 217():775-791. PubMed ID: 35839956
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13. First-in-Human Evaluation of
Wakabayashi Y; Stenkrona P; Arakawa R; Yan X; Van Buskirk MG; Jenkins MD; Santamaria JAM; Maresca KP; Takano A; Liow JS; Chappie TA; Varrone A; Nag S; Zhang L; Hughes ZA; Schmidt CJ; Doran SD; Mannes A; Zanotti-Fregonara P; Ooms M; Morse CL; Zoghbi SS; Halldin C; Pike VW; Innis RB
J Nucl Med; 2022 Dec; 63(12):1919-1924. PubMed ID: 35772961
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14. Practical Application of Rodent Transporter Knockout Models to Assess brain Penetration in Drug Discovery.
Eneberg E; Jones CR; Jensen T; Langthaler K; Bundgaard C
Drug Metab Bioanal Lett; 2022; 15(1):12-21. PubMed ID: 35196975
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15. ABCB1 limits brain exposure of the KRAS
Loos NHC; Retmana IA; Li W; Martins MLF; Lebre MC; Sparidans RW; Beijnen JH; Schinkel AH
Pharmacol Res; 2022 Apr; 178():106137. PubMed ID: 35192958
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16. Poloxamer-linked prodrug of a topoisomerase I inhibitor SN22 shows efficacy in models of high-risk neuroblastoma with primary and acquired chemoresistance.
Alferiev IS; Guerrero DT; Guan P; Nguyen F; Kolla V; Soberman D; Pressly BB; Fishbein I; Brodeur GM; Chorny M
FASEB J; 2022 Mar; 36(3):e22213. PubMed ID: 35192728
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17. Analysis of Factors Affecting 5-ALA Fluorescence Intensity in Visualizing Glial Tumor Cells-Literature Review.
Mazurek M; Szczepanek D; Orzyłowska A; Rola R
Int J Mol Sci; 2022 Jan; 23(2):. PubMed ID: 35055109
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18. ABCB1 and abcg2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.
Martínez-Chávez A; Loos NHC; Lebre MC; Tibben MM; Rosing H; Beijnen JH; Schinkel AH
Pharmacol Res; 2022 Apr; 178():105954. PubMed ID: 34700018
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19. Repurposing Vandetanib plus Everolimus for the treatment of
Carvalho DM; Richardson PJ; Olaciregui N; Stankunaite R; Lavarino C; Molinari V; Corley EA; Smith DP; Ruddle R; Donovan A; Pal A; Raynaud FI; Temelso S; Mackay A; Overington JP; Phelan A; Sheppard D; Mackinnon A; Zebian B; Al-Sarraj S; Merve A; Pryce J; Grill J; Hubank M; Cruz O; Morales La Madrid A; Mueller S; Carcaboso AM; Carceller F; Jones C
Cancer Discov; 2022 Feb; 12(2):416-431. PubMed ID: 34551970
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20. Organic Cation Transporters are Involved in Fluoxetine Transport Across the Blood-brain Barrier
Wang M; Sun Y; Hu B; He Z; Chen S; Qi D; An H; Wei Y
Curr Drug Deliv; 2022; 19(4):508-517. PubMed ID: 34238184
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