BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Clinical Outcome
31 results:

  • 1. The Role of Activation of PI3K/akt/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas-New Potential Therapeutic Approach-A Systematic Review.
    Derwich A; Sykutera M; Bromińska B; Rubiś B; Ruchała M; Sawicka-Gutaj N
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37446128
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. outcome and prognostic factors for pituitary carcinomas: lessons from a systematic review.
    Raymond P; Raverot G; Ilie MD
    Endocr Relat Cancer; 2023 May; 30(5):. PubMed ID: 36852675
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer.
    Urbaniak A; Reed MR; Heflin B; Gaydos J; Piña-Oviedo S; Jędrzejczyk M; Klejborowska G; Stępczyńska N; Chambers TC; Tackett AJ; Rodriguez A; Huczyński A; Eoff RL; MacNicol AM
    Biomed Pharmacother; 2022 Sep; 153():113440. PubMed ID: 36076555
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. CCL2 activates akt signaling to promote glycolysis and chemoresistance in glioma cells.
    Qian Y; Ding P; Xu J; Nie X; Lu B
    Cell Biol Int; 2022 May; 46(5):819-828. PubMed ID: 35178826
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
    Suwala AK; Stichel D; Schrimpf D; Kloor M; Wefers AK; Reinhardt A; Maas SLN; Kratz CP; Schweizer L; Hasselblatt M; Snuderl M; Abedalthagafi MSJ; Abdullaev Z; Monoranu CM; Bergmann M; Pekrun A; Freyschlag C; Aronica E; Kramm CM; Hinz F; Sievers P; Korshunov A; Kool M; Pfister SM; Sturm D; Jones DTW; Wick W; Unterberg A; Hartmann C; Dodgshun A; Tabori U; Wesseling P; Sahm F; von Deimling A; Reuss DE
    Acta Neuropathol; 2021 Jan; 141(1):85-100. PubMed ID: 33216206
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Intraoperative neurophysiology in pediatric supratentorial surgery: experience with 57 cases.
    Roth J; Korn A; Sala F; Benvenisti H; Jubran M; Bitan-Talmor Y; Ekstein M; Constantini S
    Childs Nerv Syst; 2020 Feb; 36(2):315-324. PubMed ID: 31422426
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-akt1 Complex Modulates Glioblastoma Therapy Sensitivity.
    Vehlow A; Klapproth E; Jin S; Hannen R; Hauswald M; Bartsch JW; Nimsky C; Temme A; Leitinger B; Cordes N
    Cell Rep; 2019 Mar; 26(13):3672-3683.e7. PubMed ID: 30917320
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/akt/MYC pathway.
    Wei C; Dong X; Lu H; Tong F; Chen L; Zhang R; Dong J; Hu Y; Wu G; Dong X
    J Exp Clin Cancer Res; 2019 Feb; 38(1):95. PubMed ID: 30791942
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Autophagy-induced KDR/VEGFR-2 activation promotes the formation of vasculogenic mimicry by glioma stem cells.
    Wu HB; Yang S; Weng HY; Chen Q; Zhao XL; Fu WJ; Niu Q; Ping YF; Wang JM; Zhang X; Yao XH; Bian XW
    Autophagy; 2017 Sep; 13(9):1528-1542. PubMed ID: 28812437
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/akt signaling in glioma.
    Song Y; Zheng S; Wang J; Long H; Fang L; Wang G; Li Z; Que T; Liu Y; Li Y; Zhang X; Fang W; Qi S
    Oncotarget; 2017 Jun; 8(26):41947-41962. PubMed ID: 28410212
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase akt.
    Hill R; Madureira PA; Ferreira B; Baptista I; Machado S; Colaço L; Dos Santos M; Liu N; Dopazo A; Ugurel S; Adrienn A; Kiss-Toth E; Isbilen M; Gure AO; Link W
    Nat Commun; 2017 Mar; 8():14687. PubMed ID: 28276427
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Therapeutic Potentials of BDNF/TrkB in Breast cancer; Current Status and Perspectives.
    Tajbakhsh A; Mokhtari-Zaer A; Rezaee M; Afzaljavan F; Rivandi M; Hassanian SM; Ferns GA; Pasdar A; Avan A
    J Cell Biochem; 2017 Sep; 118(9):2502-2515. PubMed ID: 28230291
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional PI3K inhibition.
    Craveiro RB; Ehrhardt M; Velz J; Olschewski M; Goetz B; Pietsch T; Dilloo D
    Oncotarget; 2017 Jul; 8(29):46915-46927. PubMed ID: 28159923
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. High cytotoxic T-lymphocyte-associated antigen 4 and phospho-akt expression in tumor samples predicts poor clinical outcomes in ipilimumab-treated melanoma patients.
    Chakravarti N; Ivan D; Trinh VA; Glitza IC; Curry JL; Torres-Cabala C; Tetzlaff MT; Bassett RL; Prieto VG; Hwu WJ
    Melanoma Res; 2017 Feb; 27(1):24-31. PubMed ID: 27768639
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. akt/GSK3β Signaling in Glioblastoma.
    Majewska E; Szeliga M
    Neurochem Res; 2017 Mar; 42(3):918-924. PubMed ID: 27568206
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Overexpression of TIP30 inhibits the growth and invasion of glioma cells.
    Hu Y; Chen F; Liu F; Liu X; Huang N; Cai X; Sun Y; Li A; Luo R
    Mol Med Rep; 2016 Jan; 13(1):605-12. PubMed ID: 26718891
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway.
    Dhruv HD; Roos A; Tomboc PJ; Tuncali S; Chavez A; Mathews I; Berens ME; Loftus JC; Tran NL
    J Neurooncol; 2016 Feb; 126(3):397-404. PubMed ID: 26559543
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion.
    Rao TD; Tian H; Ma X; Yan X; Thapi S; Schultz N; Rosales N; Monette S; Wang A; Hyman DM; Levine DA; Solit D; Spriggs DR
    PLoS One; 2015; 10(5):e0126633. PubMed ID: 25965947
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma.
    Wachsberger PR; Lawrence YR; Liu Y; Rice B; Feo N; Leiby B; Dicker AP
    J Cancer Res Clin Oncol; 2014 Apr; 140(4):573-82. PubMed ID: 24500492
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology.
    Ogino S; Lochhead P; Giovannucci E; Meyerhardt JA; Fuchs CS; Chan AT
    Oncogene; 2014 Jun; 33(23):2949-55. PubMed ID: 23792451
    [TBL] [Abstract] [Full Text] [Related]  


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