BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND CDKN2A, CDK4I, 1029, ENSG00000147889, P42771, p14, CMM2, ARF, TP16, p16, MTS1, p19, p16INK4a, INK4a, CDKN2, p16INK4, p14ARF, MLM, INK4 AND Clinical Outcome
32 results:

  • 1. Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas.
    Pohl LC; Leitheiser M; Obrecht D; Schweizer L; Wefers AK; Eckhardt A; Raffeld M; Sturm D; Pajtler KW; Rutkowski S; Fukuoka K; Ichimura K; Bockmayr M; Schüller U
    Acta Neuropathol; 2024 Jan; 147(1):24. PubMed ID: 38265522
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Molecular and clinical diversity in primary central nervous system lymphoma.
    Hernández-Verdin I; Kirasic E; Wienand K; Mokhtari K; Eimer S; Loiseau H; Rousseau A; Paillassa J; Ahle G; Lerintiu F; Uro-Coste E; Oberic L; Figarella-Branger D; Chinot O; Gauchotte G; Taillandier L; Marolleau JP; Polivka M; Adam C; Ursu R; Schmitt A; Barillot N; Nichelli L; Lozano-Sánchez F; Ibañez-Juliá MJ; Peyre M; Mathon B; Abada Y; Charlotte F; Davi F; Stewart C; de Reyniès A; Choquet S; Soussain C; Houillier C; Chapuy B; Hoang-Xuan K; Alentorn A
    Ann Oncol; 2023 Feb; 34(2):186-199. PubMed ID: 36402300
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Methylation subgroup and molecular heterogeneity is a hallmark of glioblastoma: implications for biopsy targeting, classification and therapy.
    Gempt J; Withake F; Aftahy AK; Meyer HS; Barz M; Delbridge C; Liesche-Starnecker F; Prokop G; Pfarr N; Schlegel J; Meyer B; Zimmer C; Menze BH; Wiestler B
    ESMO Open; 2022 Oct; 7(5):100566. PubMed ID: 36055049
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13.
    Pratt D; Abdullaev Z; Papanicolau-Sengos A; Ketchum C; Panneer Selvam P; Chung HJ; Lee I; Raffeld M; Gilbert MR; Armstrong TS; Pytel P; Borys E; Klonoski JM; McCord M; Horbinski C; Brat D; Perry A; Solomon D; Eberhart C; Giannini C; Quezado M; Aldape K
    Acta Neuropathol; 2022 Mar; 143(3):403-414. PubMed ID: 35103816
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma.
    Tang K; Kurland D; Vasudevaraja V; Serrano J; Delorenzo M; Radmanesh A; Thomas C; Spino M; Gardner S; Allen JC; Nicolaides T; Osorio DS; Finlay JL; Boué DR; Snuderl M
    J Neuropathol Exp Neurol; 2020 Aug; 79(8):880-890. PubMed ID: 32594172
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Ependymomas in infancy: underlying genetic alterations, histological features, and clinical outcome.
    Jünger ST; Andreiuolo F; Mynarek M; Dörner E; Zur Mühlen A; Rutkowski S; von Bueren AO; Pietsch T
    Childs Nerv Syst; 2020 Nov; 36(11):2693-2700. PubMed ID: 32474813
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Molecular subtyping reveals immune alterations in IDH wild-type lower-grade diffuse glioma.
    Wu F; Li GZ; Liu HJ; Zhao Z; Chai RC; Liu YQ; Jiang HY; Zhai Y; Feng YM; Li RP; Zhang W
    J Pathol; 2020 Jul; 251(3):272-283. PubMed ID: 32418210
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. clinical impact of revisions to the WHO classification of diffuse gliomas and associated future problems.
    Sonoda Y
    Int J Clin Oncol; 2020 Jun; 25(6):1004-1009. PubMed ID: 32020379
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Mitotic Index Thresholds Do Not Predict clinical outcome for IDH-Mutant Astrocytoma.
    Yoda RA; Marxen T; Longo L; Ene C; Wirsching HG; Keene CD; Holland EC; Cimino PJ
    J Neuropathol Exp Neurol; 2019 Nov; 78(11):1002-1010. PubMed ID: 31529048
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.
    Brand F; Förster A; Christians A; Bucher M; Thomé CM; Raab MS; Westphal M; Pietsch T; von Deimling A; Reifenberger G; Claus P; Hentschel B; Weller M; Weber RG
    Acta Neuropathol; 2020 Jan; 139(1):175-192. PubMed ID: 31473790
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Total copy number variation as a prognostic factor in adult astrocytoma subtypes.
    Mirchia K; Sathe AA; Walker JM; Fudym Y; Galbraith K; Viapiano MS; Corona RJ; Snuderl M; Xing C; Hatanpaa KJ; Richardson TE
    Acta Neuropathol Commun; 2019 Jun; 7(1):92. PubMed ID: 31177992
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Prognostic significance of genetic biomarkers in isocitrate dehydrogenase-wild-type lower-grade glioma: the need to further stratify this tumor entity - a meta-analysis.
    Vuong HG; Tran TTK; Ngo HTT; Pham TQ; Nakazawa T; Fung KM; Hassell L; Katoh R; Kondo T
    Eur J Neurol; 2019 Mar; 26(3):379-387. PubMed ID: 30298540
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, cdkn2a/B and ATRX alterations.
    Reinhardt A; Stichel D; Schrimpf D; Sahm F; Korshunov A; Reuss DE; Koelsche C; Huang K; Wefers AK; Hovestadt V; Sill M; Gramatzki D; Felsberg J; Reifenberger G; Koch A; Thomale UW; Becker A; Hans VH; Prinz M; Staszewski O; Acker T; Dohmen H; Hartmann C; Mueller W; Tuffaha MSA; Paulus W; Heß K; Brokinkel B; Schittenhelm J; Monoranu CM; Kessler AF; Loehr M; Buslei R; Deckert M; Mawrin C; Kohlhof P; Hewer E; Olar A; Rodriguez FJ; Giannini C; NageswaraRao AA; Tabori U; Nunes NM; Weller M; Pohl U; Jaunmuktane Z; Brandner S; Unterberg A; Hänggi D; Platten M; Pfister SM; Wick W; Herold-Mende C; Jones DTW; von Deimling A; Capper D
    Acta Neuropathol; 2018 Aug; 136(2):273-291. PubMed ID: 29564591
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. p16 Loss and E2F/cell cycle deregulation in infant posterior fossa ependymoma.
    Lummus SC; Donson AM; Gowan K; Jones KL; Vibhakar R; Foreman NK; Kleinschmidt-DeMasters BK
    Pediatr Blood Cancer; 2017 Dec; 64(12):. PubMed ID: 28548702
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Expression and prognostic significance of TCTN1 in human glioblastoma.
    Meng D; Chen Y; Zhao Y; Wang J; Yun D; Yang S; Chen J; Chen H; Lu D
    J Transl Med; 2014 Oct; 12():288. PubMed ID: 25304031
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Immunohistochemical analysis-based proteomic subclassification of newly diagnosed glioblastomas.
    Motomura K; Natsume A; Watanabe R; Ito I; Kato Y; Momota H; Nishikawa R; Mishima K; Nakasu Y; Abe T; Namba H; Nakazato Y; Tashiro H; Takeuchi I; Mori T; Wakabayashi T
    Cancer Sci; 2012 Oct; 103(10):1871-9. PubMed ID: 22747609
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Molecular characteristics of glioblastoma with 1p/19q co-deletion.
    Mizoguchi M; Yoshimoto K; Ma X; Guan Y; Hata N; Amano T; Nakamizo A; Suzuki SO; Iwaki T; Sasaki T
    Brain Tumor Pathol; 2012 Jul; 29(3):148-53. PubMed ID: 22736234
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma.
    Miller S; Rogers HA; Lyon P; Rand V; Adamowicz-Brice M; Clifford SC; Hayden JT; Dyer S; Pfister S; Korshunov A; Brundler MA; Lowe J; Coyle B; Grundy RG
    Neuro Oncol; 2011 Aug; 13(8):866-79. PubMed ID: 21798848
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.
    Motomura K; Natsume A; Kishida Y; Higashi H; Kondo Y; Nakasu Y; Abe T; Namba H; Wakai K; Wakabayashi T
    Cancer; 2011 Apr; 117(8):1721-30. PubMed ID: 21472719
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas.
    Horbinski C; Hamilton RL; Nikiforov Y; Pollack IF
    Acta Neuropathol; 2010 May; 119(5):641-9. PubMed ID: 20044755
    [TBL] [Abstract] [Full Text] [Related]  


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