Terms: = Brain cancer AND CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 AND Treatment
10 results:
1. In vitro and in vivo pharmacokinetics, disposition, and drug-drug interaction potential of tinengotinib (TT-00420), a promising investigational drug for treatment of cholangiocarcinoma and other solid tumors.
Ni S; Li L; Sun X; Wang Y; Yu Q; Wang W; Gu Z; Yu Z; Wu D; Wu F; Jiang S; Peng P
Eur J Pharm Sci; 2024 Jan; 192():106658. PubMed ID: 38048851
[TBL] [Abstract] [Full Text] [Related]
2. Identification of novel natural inhibitors targeting AKT Serine/Threonine Kinase 1 (AKT1) by computational study.
Zhong S; Zhang Z; Guo Z; Yang W; Dou G; Lv X; Wang X; Ge J; Wu B; Pan X; Wang H; Mou Y
Bioengineered; 2022 May; 13(5):12003-12020. PubMed ID: 35603567
[TBL] [Abstract] [Full Text] [Related]
3. Manipulating Estrogenic/Anti-Estrogenic Activity of Triphenylethylenes towards Development of Novel Anti-Neoplastic SERMs.
Elnakib HE; Ramsis MM; Albably NO; Vector MA; Weigand JJ; Schwedtmann K; Wober J; Zierau O; Vollmer G; Abadi AH; Ahmed NS
Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830456
[TBL] [Abstract] [Full Text] [Related]
4. Combinatorial Pharmacogenomic Algorithm is Predictive of Citalopram and Escitalopram Metabolism in Patients with Major Depressive Disorder.
Shelton RC; Parikh SV; Law RA; Rothschild AJ; Thase ME; Dunlop BW; DeBattista C; Conway CR; Forester BP; Macaluso M; Hain DT; Aguilar AL; Brown K; Lewis DJ; Jablonski MR; Greden JF
Psychiatry Res; 2020 Aug; 290():113017. PubMed ID: 32485484
[TBL] [Abstract] [Full Text] [Related]
5. Human cyp2d6 Is Functional in brain In Vivo: Evidence from Humanized cyp2d6 Transgenic Mice.
Tolledo C; Stocco MR; Miksys S; Gonzalez FJ; Tyndale RF
Mol Neurobiol; 2020 Jun; 57(6):2509-2520. PubMed ID: 32189192
[TBL] [Abstract] [Full Text] [Related]
6. Metabolic activity in the insular cortex and hypothalamus predicts hot flashes: an FDG-PET study.
Joffe H; Deckersbach T; Lin NU; Makris N; Skaar TC; Rauch SL; Dougherty DD; Hall JE
J Clin Endocrinol Metab; 2012 Sep; 97(9):3207-15. PubMed ID: 22723326
[TBL] [Abstract] [Full Text] [Related]
7. cyp2d6 genotyping and use of antidepressants in breast cancer patients: test development for clinical application.
van der Merwe N; Bouwens CS; Pienaar R; van der Merwe L; Yako YY; Geiger DH; Kotze MJ
Metab Brain Dis; 2012 Sep; 27(3):319-26. PubMed ID: 22638694
[TBL] [Abstract] [Full Text] [Related]
8. Using the literature-based discovery paradigm to investigate drug mechanisms.
Ahlers CB; Hristovski D; Kilicoglu H; Rindflesch TC
AMIA Annu Symp Proc; 2007 Oct; 2007():6-10. PubMed ID: 18693787
[TBL] [Abstract] [Full Text] [Related]
9. Molecular pathology and pharmacogenomics in Alzheimer's disease: polygenic-related effects of multifactorial treatments on cognition, anxiety and depression.
Cacabelos R
Methods Find Exp Clin Pharmacol; 2007 Jul; 29 Suppl A():1-91. PubMed ID: 17957277
[TBL] [Abstract] [Full Text] [Related]
10. Renal clearance, tissue distribution, and CA-125 responses in a phase I trial of suramin.
Hutson PR; Tutsch KD; Rago R; Arzoomanian R; Alberti D; Pomplun M; Church D; Marnocha R; Cheng AL; Kehrli N; Wilding G
Clin Cancer Res; 1998 Jun; 4(6):1429-36. PubMed ID: 9626459
[TBL] [Abstract] [Full Text] [Related]
