BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND HRAS, K-ras, 3265, ENSG00000174775, HRAS1, RASH1, c-bas/has, P01112, N-ras AND Treatment
35 results:

  • 1. k-ras Acts as a Critical Regulator of CD44 to Promote the Invasiveness and Stemness of GBM in Response to Ionizing Radiation.
    Zhao Y; Kang JH; Yoo KC; Kang SG; Lee HJ; Lee SJ
    Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681583
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme.
    Jena LN; Bennie LA; McErlean EM; Pentlavalli S; Glass K; Burrows JF; Kett VL; Buckley NE; Coulter JA; Dunne NJ; McCarthy HO
    J Nanobiotechnology; 2021 May; 19(1):127. PubMed ID: 33947409
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. SMARCB1 Gene Mutation Predisposes to Earlier Development of Glioblastoma: A Case Report of Familial GBM.
    Mukherjee S; Stroberg E; Wang F; Morales L; Shan Y; Rao A; Huang JH; Wu E; Fonkem E
    J Neuropathol Exp Neurol; 2020 May; 79(5):562-565. PubMed ID: 32296843
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Next generation sequencing identifies novel potential actionable mutations for grade I meningioma treatment.
    Pepe F; Pisapia P; Del Basso de Caro ML; Conticelli F; Malapelle U; Troncone G; Martinez JC
    Histol Histopathol; 2020 Jul; 35(7):741-749. PubMed ID: 31872418
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The antibiotic clofoctol suppresses glioma stem cell proliferation by activating KLF13.
    Hu Y; Zhang M; Tian N; Li D; Wu F; Hu P; Wang Z; Wang L; Hao W; Kang J; Yin B; Zheng Z; Jiang T; Yuan J; Qiang B; Han W; Peng X
    J Clin Invest; 2019 May; 129(8):3072-3085. PubMed ID: 31112526
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Tyrosine Kinase Inhibitor Imatinib Mesylate Alters DMBA-Induced Early Onco/Suppressor Gene Expression with Tissue-Specificity in Mice.
    Gergely PA; Murnyák B; Bencze J; Kurucz A; Varjas T; Gombos K; Hortobágyi T
    Biomed Res Int; 2019; 2019():8670398. PubMed ID: 30882001
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Failure to detect functional transfer of active k-ras protein from extracellular vesicles into recipient cells in culture.
    Luhtala N; Hunter T
    PLoS One; 2018; 13(9):e0203290. PubMed ID: 30192821
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.
    Luhtala N; Aslanian A; Yates JR; Hunter T
    J Biol Chem; 2017 Jan; 292(2):611-628. PubMed ID: 27909058
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.
    Fertig EJ; Ozawa H; Thakar M; Howard JD; Kagohara LT; Krigsfeld G; Ranaweera RS; Hughes RM; Perez J; Jones S; Favorov AV; Carey J; Stein-O'Brien G; Gaykalova DA; Ochs MF; Chung CH
    Oncotarget; 2016 Nov; 7(45):73845-73864. PubMed ID: 27650546
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Risk factors of brain metastasis during the course of EGFR-TKIs therapy for patients with EGFR-mutated advanced lung adenocarcinoma.
    Ma X; Zhu H; Guo H; Han A; Wang H; Jing W; Zhang Y; Kong L; Yu J
    Oncotarget; 2016 Dec; 7(49):81906-81917. PubMed ID: 27626317
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Upregulated miRNA-622 inhibited cell proliferation, motility, and invasion via repressing Kirsten rat sarcoma in glioblastoma.
    Wang X; Xin Z; Xu Y; Ma J
    Tumour Biol; 2016 May; 37(5):5963-70. PubMed ID: 26596833
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Somatic BRAF c.1799T>A p.V600E Mosaicism syndrome characterized by a linear syringocystadenoma papilliferum, anaplastic astrocytoma, and ocular abnormalities.
    Watanabe Y; Shido K; Niihori T; Niizuma H; Katata Y; Iizuka C; Oba D; Moriya K; Saito-Nanjo Y; Onuma M; Rikiishi T; Sasahara Y; Watanabe M; Aiba S; Saito R; Sonoda Y; Tominaga T; Aoki Y; Kure S
    Am J Med Genet A; 2016 Jan; 170A(1):189-94. PubMed ID: 26360803
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Molecular characterization of disseminated pilocytic astrocytomas.
    Gessi M; Engels AC; Lambert S; Rothämel T; von Hornstein S; Collins VP; Denkhaus D; Gnekow A; Pietsch T
    Neuropathol Appl Neurobiol; 2016 Apr; 42(3):273-8. PubMed ID: 26084390
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The profile of tumor antigens which can be targeted by immunotherapy depends upon the tumor's anatomical site.
    Alonso-Camino V; Rajani K; Kottke T; Rommelfanger-Konkol D; Zaidi S; Thompson J; Pulido J; Ilett E; Donnelly O; Selby P; Pandha H; Melcher A; Harrington K; Diaz RM; Vile R
    Mol Ther; 2014 Nov; 22(11):1936-48. PubMed ID: 25059678
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. MiR-143 acts as a tumor suppressor by targeting n-ras and enhances temozolomide-induced apoptosis in glioma.
    Wang L; Shi ZM; Jiang CF; Liu X; Chen QD; Qian X; Li DM; Ge X; Wang XF; Liu LZ; You YP; Liu N; Jiang BH
    Oncotarget; 2014 Jul; 5(14):5416-27. PubMed ID: 24980823
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and n-ras.
    Shi Z; Chen Q; Li C; Wang L; Qian X; Jiang C; Liu X; Wang X; Li H; Kang C; Jiang T; Liu LZ; You Y; Liu N; Jiang BH
    Neuro Oncol; 2014 Oct; 16(10):1341-53. PubMed ID: 24861879
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapy.
    Lin F; de Gooijer MC; Roig EM; Buil LC; Christner SM; Beumer JH; Würdinger T; Beijnen JH; van Tellingen O
    Clin Cancer Res; 2014 May; 20(10):2703-13. PubMed ID: 24647572
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists.
    Schöpel M; Jockers KF; Düppe PM; Autzen J; Potheraveedu VN; Ince S; Yip KT; Heumann R; Herrmann C; Scherkenbeck J; Stoll R
    J Med Chem; 2013 Dec; 56(23):9664-72. PubMed ID: 24266771
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature.
    Mayes DA; Rizvi TA; Titus-Mitchell H; Oberst R; Ciraolo GM; Vorhees CV; Robinson AP; Miller SD; Cancelas JA; Stemmer-Rachamimov AO; Ratner N
    Cell Rep; 2013 Sep; 4(6):1197-212. PubMed ID: 24035394
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas.
    Chaponis D; Barnes JW; Dellagatta JL; Kesari S; Fast E; Sauvageot C; Panagrahy D; Greene ER; Ramakrishna N; Wen PY; Kung AL; Stiles C; Kieran MW
    J Neurooncol; 2011 Aug; 104(1):179-89. PubMed ID: 21246394
    [TBL] [Abstract] [Full Text] [Related]  


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