Terms: = Brain cancer AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884
125 results:
1. The hsp90 inhibitor HVH-2930 exhibits potent efficacy against trastuzumab-resistant HER2-positive breast cancer.
Park M; Jung E; Park JM; Park S; Ko D; Seo J; Kim S; Nam KD; Kang YK; Farrand L; Hoang VH; Nguyen CT; La MT; Nam G; Park HJ; Ann J; Lee J; Kim YJ; Kim JY; Seo JH
Theranostics; 2024; 14(6):2442-2463. PubMed ID: 38646654
[No Abstract] [Full Text] [Related]
2. Tracing genetic diversity captures the molecular basis of misfolding disease.
Zhao P; Wang C; Sun S; Wang X; Balch WE
Nat Commun; 2024 Apr; 15(1):3333. PubMed ID: 38637533
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3. Efficient analysis of toxicity and mechanisms of environmental pollutants with network toxicology and molecular docking strategy: Acetyl tributyl citrate as an example.
Huang S
Sci Total Environ; 2023 Dec; 905():167904. PubMed ID: 37858827
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4. Post-translational regulation of proto-oncogene ZBTB7A expression by p53 status in cancer cells: hsp90-dependent stabilization vs. p53-KLHL20-ubiquitin proteasomal degradation.
Choi SH; Cho SY; Park SY; Hur MW
Biochim Biophys Acta Gene Regul Mech; 2023 Jun; 1866(2):194931. PubMed ID: 37011832
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5. ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors.
Mainwaring OJ; Weishaupt H; Zhao M; Rosén G; Borgenvik A; Breinschmid L; Verbaan AD; Richardson S; Thompson D; Clifford SC; Hill RM; Annusver K; Sundström A; Holmberg KO; Kasper M; Hutter S; Swartling FJ
Nat Commun; 2023 Mar; 14(1):1221. PubMed ID: 36869047
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6. Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8-9, 2022.
van Oosten-Hawle P; Backe SJ; Ben-Zvi A; Bourboulia D; Brancaccio M; Brodsky J; Clark M; Colombo G; Cox MB; De Los Rios P; Echtenkamp F; Edkins A; Freeman B; Goloubinoff P; Houry W; Johnson J; LaPointe P; Li W; Mezger V; Neckers L; Nillegoda NB; Prahlad V; Reitzel A; Scherz-Shouval R; Sistonen L; Tsai FTF; Woodford MR; Mollapour M; Truman AW
Cell Stress Chaperones; 2023 Jan; 28(1):1-9. PubMed ID: 36602710
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7. [Analysis of variant of GLI3 gene in a child featuring autosomal dominant Pallister-Hall syndrome].
Hou X; Wang J; Lu Y; Yu D; Yang J; Li N; Yang H; Wu K
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2023 Jan; 40(1):92-95. PubMed ID: 36585009
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8. MiR-302c-5p affects the stemness and cisplatin resistance of nasopharyngeal carcinoma cells by regulating hsp90aa1.
Zhou X; Zheng L; Zeng C; Wu Y; Tang X; Zhu Y; Tang S
Anticancer Drugs; 2023 Jan; 34(1):135-143. PubMed ID: 36539366
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9. hsp90 facilitates stemness and enhances glycolysis in glioma cells.
Kang X; Chen J; Hou JF
BMC Neurol; 2022 Nov; 22(1):420. PubMed ID: 36368999
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10. Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells.
Kıyga E; Adıgüzel Z; Önay Uçar E
Mol Biol Rep; 2022 Sep; 49(9):8701-8713. PubMed ID: 35752701
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11. The Role of Glucocorticoid Receptor in the Pathophysiology of Pituitary Corticotroph Adenomas.
Regazzo D; Mondin A; Scaroni C; Occhi G; Barbot M
Int J Mol Sci; 2022 Jun; 23(12):. PubMed ID: 35742910
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12. hsp90 induces Acsl4-dependent glioma ferroptosis via dephosphorylating Ser637 at Drp1.
Miao Z; Tian W; Ye Y; Gu W; Bao Z; Xu L; Sun G; Li C; Tu Y; Chao H; Lam SM; Liu N; Ji J
Cell Death Dis; 2022 Jun; 13(6):548. PubMed ID: 35697672
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13. A novel hsp90 inhibitor SL-145 suppresses metastatic triple-negative breast cancer without triggering the heat shock response.
Kim JY; Cho TM; Park JM; Park S; Park M; Nam KD; Ko D; Seo J; Kim S; Jung E; Farrand L; Nguyen CT; Hoang VH; Thanh La M; Ann J; Nam G; Park HJ; Lee J; Kim YJ; Seo JH
Oncogene; 2022 Jun; 41(23):3289-3297. PubMed ID: 35501463
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14. The chaperone system in glioblastoma multiforme and derived cell lines: diagnostic and mechanistic implications.
Alberti G; Campanella C; Paladino L; Porcasi R; Bavisotto CC; Pitruzzella A; Graziano F; Florena AM; Argo A; de Macario EC; Macario AJ; Cappello F; Bucchieri F; Barone R; Rappa F
Front Biosci (Landmark Ed); 2022 Mar; 27(3):97. PubMed ID: 35345329
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15. hsp90 Inhibition Overcomes Resistance to Molecular Targeted Therapy in BRAFV600E-mutant High-grade Glioma.
Sasame J; Ikegaya N; Kawazu M; Natsumeda M; Hayashi T; Isoda M; Satomi K; Tomiyama A; Oshima A; Honma H; Miyake Y; Takabayashi K; Nakamura T; Ueno T; Matsushita Y; Iwashita H; Kanemaru Y; Murata H; Ryo A; Terashima K; Yamanaka S; Fujii Y; Mano H; Komori T; Ichimura K; Cahill DP; Wakimoto H; Yamamoto T; Tateishi K
Clin Cancer Res; 2022 Jun; 28(11):2425-2439. PubMed ID: 35344043
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16. Antitumor Activity of a Mitochondrial-Targeted hsp90 Inhibitor in Gliomas.
Wei S; Yin D; Yu S; Lin X; Savani MR; Du K; Ku Y; Wu D; Li S; Liu H; Tian M; Chen Y; Bowie M; Hariharan S; Waitkus M; Keir ST; Sugarman ET; Deek RA; Labrie M; Khasraw M; Lu Y; Mills GB; Herlyn M; Wu K; Liu L; Wei Z; Flaherty KT; Abdullah K; Zhang G; Ashley DM
Clin Cancer Res; 2022 May; 28(10):2180-2195. PubMed ID: 35247901
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17. Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
Xu J; Wu PJ; Lai TH; Sharma P; Canella A; Welker AM; Beattie CE; Elder JB; Easley M; Lonser R; Jacob NK; Pietrzak M; Timmers CM; Lang F; Sampath D; Puduvalli VK
Clin Cancer Res; 2022 May; 28(9):1979-1990. PubMed ID: 35140124
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18. The Hsp70-hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration.
Bhattacharya K; Picard D
Cell Mol Life Sci; 2021 Dec; 78(23):7257-7273. PubMed ID: 34677645
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19. Preclinical Evaluation of [
Vermeulen K; Cools R; Briard E; Auberson Y; Schoepfer J; Koole M; Cawthorne C; Bormans G
ACS Chem Neurosci; 2021 Oct; 12(20):3915-3927. PubMed ID: 34597516
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20. Discovery of a simplified deguelin analog as an hsp90 C-terminal inhibitor for HER2-positive breast cancer.
Nguyen CT; Thanh La M; Ann J; Nam G; Park HJ; Min Park J; Kim YJ; Young Kim J; Hong Seo J; Lee J
Bioorg Med Chem Lett; 2021 Aug; 45():128134. PubMed ID: 34044120
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