Terms: = Brain cancer AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884 AND Treatment
52 results:
1. Efficient analysis of toxicity and mechanisms of environmental pollutants with network toxicology and molecular docking strategy: Acetyl tributyl citrate as an example.
Huang S
Sci Total Environ; 2023 Dec; 905():167904. PubMed ID: 37858827
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2. ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors.
Mainwaring OJ; Weishaupt H; Zhao M; Rosén G; Borgenvik A; Breinschmid L; Verbaan AD; Richardson S; Thompson D; Clifford SC; Hill RM; Annusver K; Sundström A; Holmberg KO; Kasper M; Hutter S; Swartling FJ
Nat Commun; 2023 Mar; 14(1):1221. PubMed ID: 36869047
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3. Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells.
Kıyga E; Adıgüzel Z; Önay Uçar E
Mol Biol Rep; 2022 Sep; 49(9):8701-8713. PubMed ID: 35752701
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4. hsp90 Inhibition Overcomes Resistance to Molecular Targeted Therapy in BRAFV600E-mutant High-grade Glioma.
Sasame J; Ikegaya N; Kawazu M; Natsumeda M; Hayashi T; Isoda M; Satomi K; Tomiyama A; Oshima A; Honma H; Miyake Y; Takabayashi K; Nakamura T; Ueno T; Matsushita Y; Iwashita H; Kanemaru Y; Murata H; Ryo A; Terashima K; Yamanaka S; Fujii Y; Mano H; Komori T; Ichimura K; Cahill DP; Wakimoto H; Yamamoto T; Tateishi K
Clin Cancer Res; 2022 Jun; 28(11):2425-2439. PubMed ID: 35344043
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5. Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
Xu J; Wu PJ; Lai TH; Sharma P; Canella A; Welker AM; Beattie CE; Elder JB; Easley M; Lonser R; Jacob NK; Pietrzak M; Timmers CM; Lang F; Sampath D; Puduvalli VK
Clin Cancer Res; 2022 May; 28(9):1979-1990. PubMed ID: 35140124
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6. The Hsp70-hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration.
Bhattacharya K; Picard D
Cell Mol Life Sci; 2021 Dec; 78(23):7257-7273. PubMed ID: 34677645
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7. Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of hsp90.
Shin SC; El-Damasy AK; Lee JH; Seo SH; Kim JH; Seo YH; Lee Y; Yu JH; Bang EK; Kim EE; Keum G
Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33317068
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8. A novel hsp90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer.
Park JM; Kim YJ; Park S; Park M; Farrand L; Nguyen CT; Ann J; Nam G; Park HJ; Lee J; Kim JY; Seo JH
Mol Cancer; 2020 Nov; 19(1):161. PubMed ID: 33218356
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9. C-terminal hsp90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Cho TM; Kim JY; Kim YJ; Sung D; Oh E; Jang S; Farrand L; Hoang VH; Nguyen CT; Ann J; Lee J; Seo JH
Cancer Lett; 2019 Apr; 447():141-153. PubMed ID: 30703411
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10. Discovery of Small-Molecule Inhibitors of the hsp90-Calcineurin-NFAT Pathway against Glioblastoma.
Liu Z; Li H; He L; Xiang Y; Tian C; Li C; Tan P; Jing J; Tian Y; Du L; Huang Y; Han L; Li M; Zhou Y
Cell Chem Biol; 2019 Mar; 26(3):352-365.e7. PubMed ID: 30639261
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11. Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy.
Wilson KM; Mathews-Griner LA; Williamson T; Guha R; Chen L; Shinn P; McKnight C; Michael S; Klumpp-Thomas C; Binder ZA; Ferrer M; Gallia GL; Thomas CJ; Riggins GJ
SLAS Technol; 2019 Feb; 24(1):28-40. PubMed ID: 30289729
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12. Recent developments and obstacles in the treatment of melanoma with BRAF and MEK inhibitors.
Wahid M; Jawed A; Mandal RK; Dar SA; Akhter N; Somvanshi P; Khan F; Lohani M; Areeshi MY; Haque S
Crit Rev Oncol Hematol; 2018 May; 125():84-88. PubMed ID: 29650281
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13. The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.
Schaefer S; Svenstrup TH; Guerra B
PLoS One; 2017; 12(5):e0177706. PubMed ID: 28542269
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14. Migration pattern, actin cytoskeleton organization and response to PI3K-, mTOR-, and hsp90-inhibition of glioblastoma cells with different invasive capacities.
Memmel S; Sisario D; Zöller C; Fiedler V; Katzer A; Heiden R; Becker N; Eing L; Ferreira FLR; Zimmermann H; Sauer M; Flentje M; Sukhorukov VL; Djuzenova CS
Oncotarget; 2017 Jul; 8(28):45298-45310. PubMed ID: 28424411
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15. Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme.
Chou ST; Patil R; Galstyan A; Gangalum PR; Cavenee WK; Furnari FB; Ljubimov VA; Chesnokova A; Kramerov AA; Ding H; Falahatian V; Mashouf L; Fox I; Black KL; Holler E; Ljubimov AV; Ljubimova JY
J Control Release; 2016 Dec; 244(Pt A):14-23. PubMed ID: 27825958
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16. CCAAT/enhancer binding protein β negatively regulates progesterone receptor expression in human glioblastoma cells.
Hansberg-Pastor V; González-Arenas A; Camacho-Arroyo I
Mol Cell Endocrinol; 2017 Jan; 439():317-327. PubMed ID: 27663075
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17. HPOB, an HDAC6 inhibitor, attenuates corticosterone-induced injury in rat adrenal pheochromocytoma PC12 cells by inhibiting mitochondrial GR translocation and the intrinsic apoptosis pathway.
Li ZY; Li QZ; Chen L; Chen BD; Zhang C; Wang X; Li WP
Neurochem Int; 2016 Oct; 99():239-251. PubMed ID: 27522966
[TBL] [Abstract] [Full Text] [Related]
18. Advances in HSP27 and hsp90-targeting strategies for glioblastoma.
van Ommeren R; Staudt MD; Xu H; Hebb MO
J Neurooncol; 2016 Apr; 127(2):209-19. PubMed ID: 26842818
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19. Breast cancer subtype as a predictor for outcomes and control in the setting of brain metastases treated with stereotactic radiosurgery.
Grubb CS; Jani A; Wu CC; Saad S; Qureshi YH; Nanda T; Yaeh A; Rozenblat T; Sisti MB; Bruce JN; McKhann GM; Sheth SA; Lesser J; Cheng SK; Isaacson SR; Lassman AB; Connolly EP; Wang TJ
J Neurooncol; 2016 Mar; 127(1):103-10. PubMed ID: 26615564
[TBL] [Abstract] [Full Text] [Related]
20. Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model.
Lo Dico A; Martelli C; Valtorta S; Raccagni I; Diceglie C; Belloli S; Gianelli U; Vaira V; Politi LS; Bosari S; Lucignani G; Moresco RM; Ottobrini L
Eur J Nucl Med Mol Imaging; 2015 Jun; 42(7):1093-105. PubMed ID: 25813354
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