BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND JAK1, ENSG00000162434, P23458, JTK3, JAK1B, JAK1A, 3716
46 results:

  • 1. Sensory neurons promote immune homeostasis in the lung.
    Tamari M; Del Bel KL; Ver Heul AM; Zamidar L; Orimo K; Hoshi M; Trier AM; Yano H; Yang TL; Biggs CM; Motomura K; Shibuya R; Yu CD; Xie Z; Iriki H; Wang Z; Auyeung K; Damle G; Demircioglu D; Gregory JK; Hasson D; Dai J; Chang RB; Morita H; Matsumoto K; Jain S; Van Dyken S; Milner JD; Bogunovic D; Hu H; Artis D; Turvey SE; Kim BS
    Cell; 2024 Jan; 187(1):44-61.e17. PubMed ID: 38134932
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation.
    Yang SR; Gedvilaite E; Ptashkin R; Chang J; Ziegler J; Mata DA; Villafania LB; Nafa K; Hechtman JF; Benayed R; Zehir A; Benhamida J; Arcila ME; Mandelker D; Rudin CM; Paik PK; Drilon A; Schoenfeld AJ; Ladanyi M
    J Thorac Oncol; 2024 Mar; 19(3):409-424. PubMed ID: 37838086
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. JAK Inhibition in Aicardi-Goutières Syndrome: a Monocentric Multidisciplinary Real-World Approach Study.
    Frémond ML; Hully M; Fournier B; Barrois R; Lévy R; Aubart M; Castelle M; Chabalier D; Gins C; Sarda E; Al Adba B; Couderc S; D' Almeida C; Berat CM; Durrleman C; Espil C; Lambert L; Méni C; Périvier M; Pillet P; Polivka L; Schiff M; Todosi C; Uettwiller F; Lepelley A; Rice GI; Seabra L; Sanquer S; Hulin A; Pressiat C; Goldwirt L; Bondet V; Duffy D; Moshous D; Bader-Meunier B; Bodemer C; Robin-Renaldo F; Boddaert N; Blanche S; Desguerre I; Crow YJ; Neven B
    J Clin Immunol; 2023 Aug; 43(6):1436-1447. PubMed ID: 37171742
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.
    Geurts BS; Battaglia TW; van Berge Henegouwen JM; Zeverijn LJ; de Wit GF; Hoes LR; van der Wijngaart H; van der Noort V; Roepman P; de Leng WWJ; Jansen AML; Opdam FL; de Jonge MJA; Cirkel GA; Labots M; Hoeben A; Kerver ED; Bins AD; Erdkamp FGL; van Rooijen JM; Houtsma D; Hendriks MP; de Groot JB; Verheul HMW; Gelderblom H; Voest EE
    BMC Cancer; 2023 Mar; 23(1):205. PubMed ID: 36870947
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Goker Bagca B; Ozates NP; Biray Avci C
    Med Oncol; 2022 Dec; 40(1):37. PubMed ID: 36460932
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Molecular and clinical diversity in primary central nervous system lymphoma.
    Hernández-Verdin I; Kirasic E; Wienand K; Mokhtari K; Eimer S; Loiseau H; Rousseau A; Paillassa J; Ahle G; Lerintiu F; Uro-Coste E; Oberic L; Figarella-Branger D; Chinot O; Gauchotte G; Taillandier L; Marolleau JP; Polivka M; Adam C; Ursu R; Schmitt A; Barillot N; Nichelli L; Lozano-Sánchez F; Ibañez-Juliá MJ; Peyre M; Mathon B; Abada Y; Charlotte F; Davi F; Stewart C; de Reyniès A; Choquet S; Soussain C; Houillier C; Chapuy B; Hoang-Xuan K; Alentorn A
    Ann Oncol; 2023 Feb; 34(2):186-199. PubMed ID: 36402300
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors.
    Zhang F; Zhang Q; Zhu J; Yao B; Ma C; Qiao N; He S; Ye Z; Wang Y; Han R; Feng J; Wang Y; Qin Z; Ma Z; Li K; Zhang Y; Tian S; Chen Z; Tan S; Wu Y; Ran P; Wang Y; Ding C; Zhao Y
    Cell Res; 2022 Dec; 32(12):1047-1067. PubMed ID: 36307579
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti-PD-1 Immunotherapy in Endometrial Carcinoma.
    Chow RD; Michaels T; Bellone S; Hartwich TMP; Bonazzoli E; Iwasaki A; Song E; Santin AD
    Cancer Discov; 2023 Feb; 13(2):312-331. PubMed ID: 36301137
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells.
    Bulstrode H; Girdler GC; Gracia T; Aivazidis A; Moutsopoulos I; Young AMH; Hancock J; He X; Ridley K; Xu Z; Stockley JH; Finlay J; Hallou C; Fajardo T; Fountain DM; van Dongen S; Joannides A; Morris R; Mair R; Watts C; Santarius T; Price SJ; Hutchinson PJA; Hodson EJ; Pollard SM; Mohorianu I; Barker RA; Sweeney TR; Bayraktar O; Gergely F; Rowitch DH
    Neuron; 2022 Dec; 110(23):3936-3951.e10. PubMed ID: 36174572
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Microsatellite Instability-High Endometrial cancers with MLH1 Promoter Hypermethylation Have Distinct Molecular and Clinical Profiles.
    Manning-Geist BL; Liu YL; Devereaux KA; Paula ADC; Zhou QC; Ma W; Selenica P; Ceyhan-Birsoy O; Moukarzel LA; Hoang T; Gordhandas S; Rubinstein MM; Friedman CF; Aghajanian C; Abu-Rustum NR; Stadler ZK; Reis-Filho JS; Iasonos A; Zamarin D; Ellenson LH; Lakhman Y; Mandelker DL; Weigelt B
    Clin Cancer Res; 2022 Oct; 28(19):4302-4311. PubMed ID: 35849120
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours.
    Larson RC; Kann MC; Bailey SR; Haradhvala NJ; Llopis PM; Bouffard AA; Scarfó I; Leick MB; Grauwet K; Berger TR; Stewart K; Anekal PV; Jan M; Joung J; Schmidts A; Ouspenskaia T; Law T; Regev A; Getz G; Maus MV
    Nature; 2022 Apr; 604(7906):563-570. PubMed ID: 35418687
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Effects of Vitexin, a Natural Flavonoid Glycoside, on the Proliferation, Invasion, and Apoptosis of Human U251 Glioblastoma Cells.
    Huang J; Zhou Y; Zhong X; Su F; Xu L
    Oxid Med Cell Longev; 2022; 2022():3129155. PubMed ID: 35281458
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape.
    Glaire MA; Ryan NA; Ijsselsteijn ME; Kedzierska K; Obolenski S; Ali R; Crosbie EJ; Bosse T; de Miranda NF; Church DN
    J Pathol; 2022 Jul; 257(3):340-351. PubMed ID: 35262923
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Association of Tim-3/Gal-9 Axis with NLRC4 Inflammasome in Glioma Malignancy: Tim-3/Gal-9 Induce the NLRC4 Inflammasome.
    Sim J; Park J; Kim S; Hwang S; Sung K; Lee JE; Yang S; Cho K; Lee S; Moon JS; Ahn J; Lim J
    Int J Mol Sci; 2022 Feb; 23(4):. PubMed ID: 35216164
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells.
    Sreenivasan L; Li LV; Leclair P; Lim CJ
    Cells; 2022 Jan; 11(3):. PubMed ID: 35159191
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Good Tumor Response to Chemoradioimmunotherapy in dMMR/MSI-H Advanced Colorectal cancer: A Case Series.
    Zhou C; Jiang T; Xiao Y; Wang Q; Zeng Z; Cai P; Zhao Y; Zhao Z; Wu D; Lin H; Sun C; Zhang R; Xiao W; Gao Y
    Front Immunol; 2021; 12():784336. PubMed ID: 34975873
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. AZD3759 enhances radiation effects in non-small-cell lung cancer by a synergistic blockade of epidermal growth factor receptor and Janus kinase-1.
    Zhao R; Yin W; Yu Q; Mao Y; Deng Q; Zhang K; Ma S
    Bioengineered; 2022 Jan; 13(1):331-344. PubMed ID: 34738874
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Repurposing Methotrexate in Dampening SARS-CoV2-S1-Mediated IL6 Expression: Lessons Learnt from Lung cancer.
    Gowda P; Patrick S; Joshi SD; Kumawat RK; Sen E
    Inflammation; 2022 Feb; 45(1):172-179. PubMed ID: 34480250
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway.
    Chen DY; Khan N; Close BJ; Goel RK; Blum B; Tavares AH; Kenney D; Conway HL; Ewoldt JK; Chitalia VC; Crossland NA; Chen CS; Kotton DN; Baker SC; Fuchs SY; Connor JH; Douam F; Emili A; Saeed M
    J Virol; 2021 Sep; 95(19):e0086221. PubMed ID: 34260266
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Immunostimulatory bacterial antigen-armed oncolytic measles virotherapy significantly increases the potency of anti-PD1 checkpoint therapy.
    Panagioti E; Kurokawa C; Viker K; Ammayappan A; Anderson SK; Sotiriou S; Chatzopoulos K; Ayasoufi K; Johnson AJ; Iankov ID; Galanis E
    J Clin Invest; 2021 Jul; 131(13):. PubMed ID: 34196308
    [TBL] [Abstract] [Full Text] [Related]  


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