BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND JAK1, ENSG00000162434, P23458, JTK3, JAK1B, JAK1A, 3716 AND Treatment
23 results:

  • 1. JAK Inhibition in Aicardi-Goutières Syndrome: a Monocentric Multidisciplinary Real-World Approach Study.
    Frémond ML; Hully M; Fournier B; Barrois R; Lévy R; Aubart M; Castelle M; Chabalier D; Gins C; Sarda E; Al Adba B; Couderc S; D' Almeida C; Berat CM; Durrleman C; Espil C; Lambert L; Méni C; Périvier M; Pillet P; Polivka L; Schiff M; Todosi C; Uettwiller F; Lepelley A; Rice GI; Seabra L; Sanquer S; Hulin A; Pressiat C; Goldwirt L; Bondet V; Duffy D; Moshous D; Bader-Meunier B; Bodemer C; Robin-Renaldo F; Boddaert N; Blanche S; Desguerre I; Crow YJ; Neven B
    J Clin Immunol; 2023 Aug; 43(6):1436-1447. PubMed ID: 37171742
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Goker Bagca B; Ozates NP; Biray Avci C
    Med Oncol; 2022 Dec; 40(1):37. PubMed ID: 36460932
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors.
    Zhang F; Zhang Q; Zhu J; Yao B; Ma C; Qiao N; He S; Ye Z; Wang Y; Han R; Feng J; Wang Y; Qin Z; Ma Z; Li K; Zhang Y; Tian S; Chen Z; Tan S; Wu Y; Ran P; Wang Y; Ding C; Zhao Y
    Cell Res; 2022 Dec; 32(12):1047-1067. PubMed ID: 36307579
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells.
    Bulstrode H; Girdler GC; Gracia T; Aivazidis A; Moutsopoulos I; Young AMH; Hancock J; He X; Ridley K; Xu Z; Stockley JH; Finlay J; Hallou C; Fajardo T; Fountain DM; van Dongen S; Joannides A; Morris R; Mair R; Watts C; Santarius T; Price SJ; Hutchinson PJA; Hodson EJ; Pollard SM; Mohorianu I; Barker RA; Sweeney TR; Bayraktar O; Gergely F; Rowitch DH
    Neuron; 2022 Dec; 110(23):3936-3951.e10. PubMed ID: 36174572
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Microsatellite Instability-High Endometrial cancers with MLH1 Promoter Hypermethylation Have Distinct Molecular and Clinical Profiles.
    Manning-Geist BL; Liu YL; Devereaux KA; Paula ADC; Zhou QC; Ma W; Selenica P; Ceyhan-Birsoy O; Moukarzel LA; Hoang T; Gordhandas S; Rubinstein MM; Friedman CF; Aghajanian C; Abu-Rustum NR; Stadler ZK; Reis-Filho JS; Iasonos A; Zamarin D; Ellenson LH; Lakhman Y; Mandelker DL; Weigelt B
    Clin Cancer Res; 2022 Oct; 28(19):4302-4311. PubMed ID: 35849120
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours.
    Larson RC; Kann MC; Bailey SR; Haradhvala NJ; Llopis PM; Bouffard AA; Scarfó I; Leick MB; Grauwet K; Berger TR; Stewart K; Anekal PV; Jan M; Joung J; Schmidts A; Ouspenskaia T; Law T; Regev A; Getz G; Maus MV
    Nature; 2022 Apr; 604(7906):563-570. PubMed ID: 35418687
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Effects of Vitexin, a Natural Flavonoid Glycoside, on the Proliferation, Invasion, and Apoptosis of Human U251 Glioblastoma Cells.
    Huang J; Zhou Y; Zhong X; Su F; Xu L
    Oxid Med Cell Longev; 2022; 2022():3129155. PubMed ID: 35281458
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells.
    Sreenivasan L; Li LV; Leclair P; Lim CJ
    Cells; 2022 Jan; 11(3):. PubMed ID: 35159191
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Good Tumor Response to Chemoradioimmunotherapy in dMMR/MSI-H Advanced Colorectal cancer: A Case Series.
    Zhou C; Jiang T; Xiao Y; Wang Q; Zeng Z; Cai P; Zhao Y; Zhao Z; Wu D; Lin H; Sun C; Zhang R; Xiao W; Gao Y
    Front Immunol; 2021; 12():784336. PubMed ID: 34975873
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. AZD3759 enhances radiation effects in non-small-cell lung cancer by a synergistic blockade of epidermal growth factor receptor and Janus kinase-1.
    Zhao R; Yin W; Yu Q; Mao Y; Deng Q; Zhang K; Ma S
    Bioengineered; 2022 Jan; 13(1):331-344. PubMed ID: 34738874
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Repurposing Methotrexate in Dampening SARS-CoV2-S1-Mediated IL6 Expression: Lessons Learnt from Lung cancer.
    Gowda P; Patrick S; Joshi SD; Kumawat RK; Sen E
    Inflammation; 2022 Feb; 45(1):172-179. PubMed ID: 34480250
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Immunostimulatory bacterial antigen-armed oncolytic measles virotherapy significantly increases the potency of anti-PD1 checkpoint therapy.
    Panagioti E; Kurokawa C; Viker K; Ammayappan A; Anderson SK; Sotiriou S; Chatzopoulos K; Ayasoufi K; Johnson AJ; Iankov ID; Galanis E
    J Clin Invest; 2021 Jul; 131(13):. PubMed ID: 34196308
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. TROY signals through jak1-STAT3 to promote glioblastoma cell migration and resistance.
    Ding Z; Kloss JM; Tuncali S; Tran NL; Loftus JC
    Neoplasia; 2020 Sep; 22(9):352-364. PubMed ID: 32629176
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Targeting Upstream Kinases of STAT3 in Human Medulloblastoma Cells.
    Wei J; Ma L; Li C; Pierson CR; Finlay JL; Lin J
    Curr Cancer Drug Targets; 2019; 19(7):571-582. PubMed ID: 30332965
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Lycopene treatment inhibits activation of jak1/Stat3 and Wnt/β-catenin signaling and attenuates hyperproliferation in gastric epithelial cells.
    Park B; Lim JW; Kim H
    Nutr Res; 2019 Oct; 70():70-81. PubMed ID: 30098838
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. OSU-03012 and Viagra treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood-brain Barrier: Implications for Anti-cancer Therapies.
    Booth L; Roberts JL; Tavallai M; Nourbakhsh A; Chuckalovcak J; Carter J; Poklepovic A; Dent P
    J Cell Physiol; 2015 Aug; 230(8):1982-98. PubMed ID: 25736380
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Progesterone-induced blocking factor is hormonally regulated in human astrocytoma cells, and increases their growth through the IL-4R/jak1/STAT6 pathway.
    González-Arenas A; Valadez-Cosmes P; Jiménez-Arellano C; López-Sánchez M; Camacho-Arroyo I
    J Steroid Biochem Mol Biol; 2014 Oct; 144 Pt B():463-70. PubMed ID: 25218441
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.
    Anderson JC; Duarte CW; Welaya K; Rohrbach TD; Bredel M; Yang ES; Choradia NV; Thottassery JV; Yancey Gillespie G; Bonner JA; Willey CD
    Radiother Oncol; 2014 Jun; 111(3):468-74. PubMed ID: 24813092
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the jak1/2 inhibitor, CYT387.
    Durmus S; Xu N; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
    Pharmacol Res; 2013 Oct; 76():9-16. PubMed ID: 23827160
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Therapeutic potential of AZD1480 for the treatment of human glioblastoma.
    McFarland BC; Ma JY; Langford CP; Gillespie GY; Yu H; Zheng Y; Nozell SE; Huszar D; Benveniste EN
    Mol Cancer Ther; 2011 Dec; 10(12):2384-93. PubMed ID: 22027691
    [TBL] [Abstract] [Full Text] [Related]  


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