Terms: = Brain cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132
43 results:
1. Sotorasib in KRAS G12C-mutated non-small cell lung cancer: A multicenter real-world experience from the compassionate use program in Germany.
Stratmann JA; Althoff FC; Doebel P; Rauh J; Trummer A; Hünerlitürkoglu AN; Frost N; Yildirim H; Christopoulos P; Burkhard O; Büschenfelde CMZ; Becker von Rose A; Alt J; Aries SP; Webendörfer M; Kaldune S; Uhlenbruch M; Tritchkova G; Waller CF; Rittmeyer A; Hoffknecht P; Braess J; Kopp HG; Grohé C; Schäfer M; Schumann C; Griesinger F; Kuon J; Sebastian M; Reinmuth N
Eur J Cancer; 2024 Apr; 201():113911. PubMed ID: 38377774
[TBL] [Abstract] [Full Text] [Related]
2. The preventive effects of broccoli bioactives against cancer: Evidence from a validated rat glioma model.
Baenas N; Vega-García A; Manjarrez-Marmolejo J; Moreno DA; Feria-Romero IA
Biomed Pharmacother; 2023 Dec; 168():115720. PubMed ID: 37839110
[TBL] [Abstract] [Full Text] [Related]
3. Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation.
Yang SR; Gedvilaite E; Ptashkin R; Chang J; Ziegler J; Mata DA; Villafania LB; Nafa K; Hechtman JF; Benayed R; Zehir A; Benhamida J; Arcila ME; Mandelker D; Rudin CM; Paik PK; Drilon A; Schoenfeld AJ; Ladanyi M
J Thorac Oncol; 2024 Mar; 19(3):409-424. PubMed ID: 37838086
[TBL] [Abstract] [Full Text] [Related]
4. FSP1 confers ferroptosis resistance in keap1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner.
Kim JW; Kim MJ; Han TH; Lee JY; Kim S; Kim H; Oh KJ; Kim WK; Han BS; Bae KH; Ban HS; Bae SH; Lee SC; Lee H; Lee EW
Cell Death Dis; 2023 Aug; 14(8):567. PubMed ID: 37633973
[TBL] [Abstract] [Full Text] [Related]
5. The Role of CDK20 Protein in Carcinogenesis.
Chivukula S; Malkhed V
Curr Drug Targets; 2023; 24(10):790-796. PubMed ID: 37469151
[TBL] [Abstract] [Full Text] [Related]
6. Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.
Ikeda R; Noshiro D; Morishita H; Takada S; Kageyama S; Fujioka Y; Funakoshi T; Komatsu-Hirota S; Arai R; Ryzhii E; Abe M; Koga T; Motohashi H; Nakao M; Sakimura K; Horii A; Waguri S; Ichimura Y; Noda NN; Komatsu M
EMBO J; 2023 Jul; 42(14):e113349. PubMed ID: 37306101
[TBL] [Abstract] [Full Text] [Related]
7. Inflammation and immune cell abnormalities in intracranial aneurysm subarachnoid hemorrhage (SAH): Relevant signaling pathways and therapeutic strategies.
Jin J; Duan J; Du L; Xing W; Peng X; Zhao Q
Front Immunol; 2022; 13():1027756. PubMed ID: 36505409
[TBL] [Abstract] [Full Text] [Related]
8. Transcription factor Nrf2 binds to circRNAPIBF1 to regulate SOD2 in lung adenocarcinoma progression.
Zhang Z; Chen Q; Huang C; Rao D; Sang C; Zhu S; Gu L; Xie C; Tang Z; Xu X
Mol Carcinog; 2022 Dec; 61(12):1161-1176. PubMed ID: 36193777
[TBL] [Abstract] [Full Text] [Related]
9. A uniformity correction method to reduce scan time for 7T sodium imaging of brain tumors.
Kim S; Merugumala S; Lin AP
J Neuroimaging; 2022 Nov; 32(6):1062-1069. PubMed ID: 35989449
[TBL] [Abstract] [Full Text] [Related]
10. Apatinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 Pathway.
Xia L; Gong M; Zou Y; Wang Z; Wu B; Zhang S; Li L; Jin K; Sun C
Oxid Med Cell Longev; 2022; 2022():9925919. PubMed ID: 35602105
[TBL] [Abstract] [Full Text] [Related]
11. Clinicopathologic and Genomic Landscape of Non-Small Cell Lung cancer brain Metastases.
Huang RSP; Harries L; Decker B; Hiemenz MC; Murugesan K; Creeden J; Tolba K; Stabile LP; Ramkissoon SH; Burns TF; Ross JS
Oncologist; 2022 Oct; 27(10):839-848. PubMed ID: 35598205
[TBL] [Abstract] [Full Text] [Related]
12. Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing keap1/NRF2 and CBS-regulated ferroptosis.
Zheng XJ; Chen WL; Yi J; Li W; Liu JY; Fu WQ; Ren LW; Li S; Ge BB; Yang YH; Zhang YZ; Yang H; Du GH; Wang Y; Wang JH
Acta Pharmacol Sin; 2022 Nov; 43(11):2977-2992. PubMed ID: 35581292
[TBL] [Abstract] [Full Text] [Related]
13. Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic Prospects.
Shahcheraghi SH; Salemi F; Peirovi N; Ayatollahi J; Alam W; Khan H; Saso L
Molecules; 2021 Dec; 27(1):. PubMed ID: 35011412
[TBL] [Abstract] [Full Text] [Related]
14. Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases.
Xu Y; Huang Z; Yu X; Chen K; Fan Y
Mol Brain; 2021 Dec; 14(1):176. PubMed ID: 34952628
[TBL] [Abstract] [Full Text] [Related]
15. Impact of Tumor Suppressor Gene Co-Mutations on Differential Response to EGFR TKI Therapy in EGFR L858R and Exon 19 Deletion Lung cancer.
Hellyer JA; White MN; Gardner RM; Cunanan K; Padda SK; Das M; Ramchandran K; Neal JW; Wakelee HA
Clin Lung Cancer; 2022 May; 23(3):264-272. PubMed ID: 34838441
[TBL] [Abstract] [Full Text] [Related]
16. Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome.
Unterman I; Bloch I; Cazacu S; Kazimirsky G; Ben-Zeev B; Berman BP; Brodie C; Tabach Y
Elife; 2021 Aug; 10():. PubMed ID: 34355696
[TBL] [Abstract] [Full Text] [Related]
17. Lung adenocarcinoma patients with keap1 mutation harboring low immune cell infiltration and low activity of immune environment.
Cheng W; Xu B; Zhang H; Fang S
Thorac Cancer; 2021 Sep; 12(18):2458-2467. PubMed ID: 34328274
[TBL] [Abstract] [Full Text] [Related]
18. Optimization of 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acids as inhibitors of keap1-Nrf2 protein-protein interaction to suppress neuroinflammation.
Abed DA; Lee S; Wen X; Ali AR; Mangipudy V; Aleksunes LM; Hu L
Bioorg Med Chem; 2021 Aug; 44():116300. PubMed ID: 34252790
[TBL] [Abstract] [Full Text] [Related]
19. p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Kageyama S; Gudmundsson SR; Sou YS; Ichimura Y; Tamura N; Kazuno S; Ueno T; Miura Y; Noshiro D; Abe M; Mizushima T; Miura N; Okuda S; Motohashi H; Lee JA; Sakimura K; Ohe T; Noda NN; Waguri S; Eskelinen EL; Komatsu M
Nat Commun; 2021 Jan; 12(1):16. PubMed ID: 33397898
[TBL] [Abstract] [Full Text] [Related]
20. Epigenetics of Muscle- and brain-Specific Expression of KLHL Family Genes.
Ehrlich KC; Baribault C; Ehrlich M
Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33182325
[No Abstract] [Full Text] [Related]
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