Terms: = Brain cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132 AND Treatment
15 results:
1. Sotorasib in KRAS G12C-mutated non-small cell lung cancer: A multicenter real-world experience from the compassionate use program in Germany.
Stratmann JA; Althoff FC; Doebel P; Rauh J; Trummer A; Hünerlitürkoglu AN; Frost N; Yildirim H; Christopoulos P; Burkhard O; Büschenfelde CMZ; Becker von Rose A; Alt J; Aries SP; Webendörfer M; Kaldune S; Uhlenbruch M; Tritchkova G; Waller CF; Rittmeyer A; Hoffknecht P; Braess J; Kopp HG; Grohé C; Schäfer M; Schumann C; Griesinger F; Kuon J; Sebastian M; Reinmuth N
Eur J Cancer; 2024 Apr; 201():113911. PubMed ID: 38377774
[TBL] [Abstract] [Full Text] [Related]
2. Apatinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 Pathway.
Xia L; Gong M; Zou Y; Wang Z; Wu B; Zhang S; Li L; Jin K; Sun C
Oxid Med Cell Longev; 2022; 2022():9925919. PubMed ID: 35602105
[TBL] [Abstract] [Full Text] [Related]
3. Clinicopathologic and Genomic Landscape of Non-Small Cell Lung cancer brain Metastases.
Huang RSP; Harries L; Decker B; Hiemenz MC; Murugesan K; Creeden J; Tolba K; Stabile LP; Ramkissoon SH; Burns TF; Ross JS
Oncologist; 2022 Oct; 27(10):839-848. PubMed ID: 35598205
[TBL] [Abstract] [Full Text] [Related]
4. Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases.
Xu Y; Huang Z; Yu X; Chen K; Fan Y
Mol Brain; 2021 Dec; 14(1):176. PubMed ID: 34952628
[TBL] [Abstract] [Full Text] [Related]
5. Impact of Tumor Suppressor Gene Co-Mutations on Differential Response to EGFR TKI Therapy in EGFR L858R and Exon 19 Deletion Lung cancer.
Hellyer JA; White MN; Gardner RM; Cunanan K; Padda SK; Das M; Ramchandran K; Neal JW; Wakelee HA
Clin Lung Cancer; 2022 May; 23(3):264-272. PubMed ID: 34838441
[TBL] [Abstract] [Full Text] [Related]
6. Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome.
Unterman I; Bloch I; Cazacu S; Kazimirsky G; Ben-Zeev B; Berman BP; Brodie C; Tabach Y
Elife; 2021 Aug; 10():. PubMed ID: 34355696
[TBL] [Abstract] [Full Text] [Related]
7. Optimization of 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acids as inhibitors of keap1-Nrf2 protein-protein interaction to suppress neuroinflammation.
Abed DA; Lee S; Wen X; Ali AR; Mangipudy V; Aleksunes LM; Hu L
Bioorg Med Chem; 2021 Aug; 44():116300. PubMed ID: 34252790
[TBL] [Abstract] [Full Text] [Related]
8. Withdrawal of Life-supporting treatment in Severe Traumatic brain Injury.
Williamson T; Ryser MD; Ubel PA; Abdelgadir J; Spears CA; Liu B; Komisarow J; Lemmon ME; Elsamadicy A; Lad SP
JAMA Surg; 2020 Aug; 155(8):723-731. PubMed ID: 32584926
[TBL] [Abstract] [Full Text] [Related]
9. Inhibition of Nrf2 might enhance the anti-tumor effect of temozolomide in glioma cells via inhibition of Ras/Raf/MEK signaling pathway.
Sun W; Zhang W; Yu J; Lu Z; Yu J
Int J Neurosci; 2021 Oct; 131(10):975-983. PubMed ID: 32378973
[TBL] [Abstract] [Full Text] [Related]
10. Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis.
Wang P; Geng J; Gao J; Zhao H; Li J; Shi Y; Yang B; Xiao C; Linghu Y; Sun X; Chen X; Hong L; Qin F; Li X; Yu JS; You H; Yuan Z; Zhou D; Johnson RL; Chen L
Nat Commun; 2019 Feb; 10(1):755. PubMed ID: 30765703
[TBL] [Abstract] [Full Text] [Related]
11. Chemistry-First Approach for Nomination of Personalized treatment in Lung cancer.
McMillan EA; Ryu MJ; Diep CH; Mendiratta S; Clemenceau JR; Vaden RM; Kim JH; Motoyaji T; Covington KR; Peyton M; Huffman K; Wu X; Girard L; Sung Y; Chen PH; Mallipeddi PL; Lee JY; Hanson J; Voruganti S; Yu Y; Park S; Sudderth J; DeSevo C; Muzny DM; Doddapaneni H; Gazdar A; Gibbs RA; Hwang TH; Heymach JV; Wistuba I; Coombes KR; Williams NS; Wheeler DA; MacMillan JB; Deberardinis RJ; Roth MG; Posner BA; Minna JD; Kim HS; White MA
Cell; 2018 May; 173(4):864-878.e29. PubMed ID: 29681454
[TBL] [Abstract] [Full Text] [Related]
12. Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
Wu G; Zhu L; Yuan X; Chen H; Xiong R; Zhang S; Cheng H; Shen Y; An H; Li T; Li H; Zhang W
Antioxid Redox Signal; 2017 Oct; 27(11):754-768. PubMed ID: 28186440
[TBL] [Abstract] [Full Text] [Related]
13. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.
Lee DH; Han DH; Nam KT; Park JS; Kim SH; Lee M; Kim G; Min BS; Cha BS; Lee YS; Sung SH; Jeong H; Ji HW; Lee MJ; Lee JS; Lee HY; Chun Y; Kim J; Komatsu M; Lee YH; Bae SH
Free Radic Biol Med; 2016 Oct; 99():520-532. PubMed ID: 27634173
[TBL] [Abstract] [Full Text] [Related]
14. Seaweed extracts and unsaturated fatty acid constituents from the green alga Ulva lactuca as activators of the cytoprotective Nrf2-ARE pathway.
Wang R; Paul VJ; Luesch H
Free Radic Biol Med; 2013 Apr; 57():141-53. PubMed ID: 23291594
[TBL] [Abstract] [Full Text] [Related]
15. Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line.
Zhou Y; Wang HD; Zhu L; Cong ZX; Li N; Ji XJ; Pan H; Wang JW; Li WC
Oncol Rep; 2013 Jan; 29(1):394-400. PubMed ID: 23128449
[TBL] [Abstract] [Full Text] [Related]
