Terms: = Brain cancer AND KLK2, P20151, 3817, ENSG00000167751, MGC12201, hK2, KLK2A2
46 results:
1. A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma.
Singh S; Lathoria K; Umdor SB; Singh J; Suri V; Sen E
Cytokine; 2024 Apr; 176():156535. PubMed ID: 38325141
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2. AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth.
Yun HJ; Li M; Guo D; Jeon SM; Park SH; Lim JS; Lee SB; Liu R; Du L; Kim SH; Shin TH; Eyun SI; Park YY; Lu Z; Lee JH
J Exp Clin Cancer Res; 2023 Dec; 42(1):340. PubMed ID: 38098117
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3. STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting hk2.
Zhang L; Jiang C; Zhong Y; Sun K; Jing H; Song J; Xie J; Zhou Y; Tian M; Zhang C; Sun X; Wang S; Cheng X; Zhang Y; Wei W; Li X; Fu B; Feng P; Wu B; Shu HB; Zhang J
Nat Cell Biol; 2023 Aug; 25(8):1208-1222. PubMed ID: 37443289
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4. A pan-cancer analysis of the role of hexokinase II (hk2) in human tumors.
Li R; Mei S; Ding Q; Wang Q; Yu L; Zi F
Sci Rep; 2022 Nov; 12(1):18807. PubMed ID: 36335239
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5. Homeobox A3 and KDM6A cooperate in transcriptional control of aerobic glycolysis and glioblastoma progression.
Yang R; Zhang G; Dong Z; Wang S; Li Y; Lian F; Liu X; Li H; Wei X; Cui H
Neuro Oncol; 2023 Apr; 25(4):635-647. PubMed ID: 36215227
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6. Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα.
Guo D; Tong Y; Jiang X; Meng Y; Jiang H; Du L; Wu Q; Li S; Luo S; Li M; Xiao L; He H; He X; Yu Q; Fang J; Lu Z
Cell Metab; 2022 Sep; 34(9):1312-1324.e6. PubMed ID: 36007522
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7. The expression of Hexokinase 2 and its hub genes are correlated with the prognosis in glioma.
Huang Y; Ouyang F; Yang F; Zhang N; Zhao W; Xu H; Yang X
BMC Cancer; 2022 Aug; 22(1):900. PubMed ID: 35982398
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8. Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer.
Jiang H; Wei H; Wang H; Wang Z; Li J; Ou Y; Xiao X; Wang W; Chang A; Sun W; Zhao L; Yang S
Cell Death Dis; 2022 Mar; 13(3):206. PubMed ID: 35246504
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9. Comprehensive overview of extracellular vesicle proteomics in meningioma: future strategy.
Rana R; Sharma S; Ganguly NK
Mol Biol Rep; 2021 Dec; 48(12):8061-8074. PubMed ID: 34687392
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10. Glioma glycolipid metabolism: MSI2-SNORD12B-FIP1L1-ZBTB4 feedback loop as a potential treatment target.
Dong W; Liu X; Yang C; Wang D; Xue Y; Ruan X; Zhang M; Song J; Cai H; Zheng J; Liu Y
Clin Transl Med; 2021 May; 11(5):e411. PubMed ID: 34047477
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11. miR-542-3p Contributes to the hk2-Mediated High Glycolytic Phenotype in Human Glioma Cells.
Kim J; Park MW; Park YJ; Ahn JW; Sim JM; Kim S; Heo J; Jeong JH; Lee M; Lim J; Moon JS
Genes (Basel); 2021 Apr; 12(5):. PubMed ID: 33922649
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12. Inhibition of lncRNA-UCA1 suppresses pituitary cancer cell growth and prolactin (PRL) secretion via attenuating glycolysis pathway.
Liu G; Wang L; Li Y
In Vitro Cell Dev Biol Anim; 2020 Sep; 56(8):642-649. PubMed ID: 32909148
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13. Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection.
Lee YR; Wu SY; Chen RY; Lin YS; Yeh TM; Liu HS
Kaohsiung J Med Sci; 2020 Nov; 36(11):911-919. PubMed ID: 32783363
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14. Expression of hypoxia-inducible factor 1α, glucose transporter 1, and hexokinase 2 in primary central nervous system lymphoma and the correlation with the biological behaviors.
Shen N; Wang Y; Sun X; Bai X; He J; Cui Q; Qian J; Zhu H; Chen Y; Xing R; Liu Q; Wu Y; Li J; Lai W; Sun S; Ji N; Liu Y
Brain Behav; 2020 Aug; 10(8):e01718. PubMed ID: 32533646
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15. A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone.
Chen CD; Rudy MA; Zeldich E; Abraham CR
FASEB J; 2020 Jun; 34(6):7234-7246. PubMed ID: 32347987
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16. HOTAIR/miR-125 axis-mediated Hexokinase 2 expression promotes chemoresistance in human glioblastoma.
Zhang J; Chen G; Gao Y; Liang H
J Cell Mol Med; 2020 May; 24(10):5707-5717. PubMed ID: 32279420
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17. Identification of anaplastic lymphoma kinase fusions in clear cell renal cell carcinoma.
Chen W; Li W; Bai B; Wei H
Oncol Rep; 2020 Mar; 43(3):817-826. PubMed ID: 32020234
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18. High expression of ALDH1A3 might independently influence poor progression-free and overall survival in patients with glioma via maintaining glucose uptake and lactate production.
Ni W; Xia Y; Luo L; Wen F; Hu D; Bi Y; Qi J
Cell Biol Int; 2020 Feb; 44(2):569-582. PubMed ID: 31642564
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19. Fubp1 supports the lactate-Akt-mTOR axis through the upregulation of Hk1 and hk2.
Kang M; Lee SM; Kim W; Lee KH; Kim DY
Biochem Biophys Res Commun; 2019 Apr; 512(1):93-99. PubMed ID: 30871777
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20. Kidney-differentiated cells derived from Lowe Syndrome patient's iPSCs show ciliogenesis defects and Six2 retention at the Golgi complex.
Hsieh WC; Ramadesikan S; Fekete D; Aguilar RC
PLoS One; 2018; 13(2):e0192635. PubMed ID: 29444177
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