BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7
59 results:

  • 1. Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.
    Ozyerli-Goknar E; Kala EY; Aksu AC; Bulut I; Cingöz A; Nizamuddin S; Biniossek M; Seker-Polat F; Morova T; Aztekin C; Kung SHY; Syed H; Tuncbag N; Gönen M; Philpott M; Cribbs AP; Acilan C; Lack NA; Onder TT; Timmers HTM; Bagci-Onder T
    Cell Commun Signal; 2023 Nov; 21(1):328. PubMed ID: 37974198
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Covariation of preadult environmental exposures, adult brain imaging phenotypes, and adult personality traits.
    Xue K; Gao B; Chen F; Wang M; Cheng J; Zhang B; Zhu W; Qiu S; Geng Z; Zhang X; Cui G; Yu Y; Zhang Q; Liao W; Zhang H; Xu X; Han T; Qin W; Liu F; Liang M; Guo L; Xu Q; Xu J; Fu J; Zhang P; Li W; Shi D; Wang C; Lui S; Yan Z; Zhang J; Li J; Wang D; Xian J; Xu K; Zuo XN; Zhang L; Ye Z; Banaschewski T; Barker GJ; Bokde ALW; Desrivières S; Flor H; Grigis A; Garavan H; Gowland P; Heinz A; Brühl R; Martinot JL; Martinot MP; Artiges E; Nees F; Orfanos DP; Lemaitre H; Poustka L; Hohmann S; Holz N; Fröhner JH; Smolka MN; Vaidya N; Walter H; Whelan R; Shen W; Miao Y; Yu C; ;
    Mol Psychiatry; 2023 Nov; 28(11):4853-4866. PubMed ID: 37737484
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Intracerebral Hemorrhage Among Blood Donors and Their Transfusion Recipients.
    Zhao J; Rostgaard K; Lauwers E; Dahlén T; Ostrowski SR; Erikstrup C; Pedersen OB; de Strooper B; Lemmens R; Hjalgrim H; Edgren G
    JAMA; 2023 Sep; 330(10):941-950. PubMed ID: 37698562
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Transcription factor abnormalities in B-ALL leukemogenesis and treatment.
    Yin H; Wang J; Tan Y; Jiang M; Zhang H; Meng G
    Trends Cancer; 2023 Oct; 9(10):855-870. PubMed ID: 37407363
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Nanoparticles Hitchhike on Monocytes for Glioblastoma Treatment after Low-Dose Radiotherapy.
    Kuang J; Rao ZY; Zheng DW; Kuang D; Huang QX; Pan T; Li H; Zeng X; Zhang XZ
    ACS Nano; 2023 Jul; 17(14):13333-13347. PubMed ID: 37404077
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Health-related quality of life and cognitive failures in patients with lower-grade gliomas treated with radiotherapy.
    Di Perri D; Jmil S; Lawson TM; Van Calster L; Whenham N; Renard L
    Cancer Radiother; 2023 May; 27(3):219-224. PubMed ID: 37080857
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
    Liao X; Li Z; Zheng H; Qian W; Zhang S; Chen S; Li X; Tang M; Xu Y; Yu R; Li M; Song L; Li J
    Mol Cancer Res; 2023 Jul; 21(7):648-663. PubMed ID: 36961398
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene.
    Jurutka PW; di Martino O; Reshi S; Mallick S; Sausedo MA; Moen GA; Lee IJ; Ivan DJ; Krall TD; Peoples SJ; Perez A; Tromba L; Le A; Khadka I; Petros R; Savage BM; Salama E; Salama J; Ziller JW; Noh Y; Lee MY; Liu W; Welch JS; Marshall PA; Wagner CE
    Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555852
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. kmt2a-D pathogenicity, prevalence, and variation according to a population database.
    Larson JK; Hunter-Schlichting DN; Crowgey EL; Mills LJ; Druley TE; Marcotte EL
    Cancer Med; 2023 Mar; 12(6):7234-7245. PubMed ID: 36479909
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. A clustering of heterozygous missense variants in the crucial chromatin modifier WDR5 defines a new neurodevelopmental disorder.
    Snijders Blok L; Verseput J; Rots D; Venselaar H; Innes AM; Stumpel C; Õunap K; Reinson K; Seaby EG; McKee S; Burton B; Kim K; van Hagen JM; Waisfisz Q; Joset P; Steindl K; Rauch A; Li D; Zackai EH; Sheppard SE; Keena B; Hakonarson H; Roos A; Kohlschmidt N; Cereda A; Iascone M; Rebessi E; Kernohan KD; Campeau PM; Millan F; Taylor JA; Lochmüller H; Higgs MR; Goula A; Bernhard B; Velasco DJ; Schmanski AA; Stark Z; Gallacher L; Pais L; Marcogliese PC; Yamamoto S; Raun N; Jakub TE; Kramer JM; den Hoed J; Fisher SE; Brunner HG; Kleefstra T
    HGG Adv; 2023 Jan; 4(1):100157. PubMed ID: 36408368
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Thioredoxin System and miR-21, miR-23a/b and let-7a as Potential Biomarkers for brain Tumor Progression: Preliminary Case Data.
    Kılıç N; Boyacıoğlu Ö; Saltoğlu GT; Bulduk EB; Kurt G; Korkusuz P
    World Neurosurg; 2022 Nov; 167():e1299-e1309. PubMed ID: 36096386
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Recurrent Translocations in Topoisomerase Inhibitor-Related Leukemia Are Determined by the Features of DNA Breaks Rather Than by the Proximity of the Translocating Genes.
    Lomov NA; Viushkov VS; Ulianov SV; Gavrilov AA; Alexeyevsky DA; Artemov AV; Razin SV; Rubtsov MA
    Int J Mol Sci; 2022 Aug; 23(17):. PubMed ID: 36077220
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Diallyl trisulfide sensitizes radiation therapy on glioblastoma through directly targeting thioredoxin 1.
    Tian Y; Ge Z; Xu M; Ge X; Zhao M; Ding F; Yin J; Wang X; You Y; Shi Z; Qian X
    Free Radic Biol Med; 2022 Aug; 189():157-168. PubMed ID: 35921994
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Combining hyperintense FLAIR rim and radiological features in identifying IDH mutant 1p/19q non-codeleted lower-grade glioma.
    Li M; Ren X; Chen X; Wang J; Shen S; Jiang H; Yang C; Zhao X; Zhu Q; Cui Y; Lin S
    Eur Radiol; 2022 Jun; 32(6):3869-3879. PubMed ID: 35079884
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. All-trans retinoic acid induces differentiation in primary acute myeloid leukemia blasts carrying an inversion of chromosome 16.
    Dembitz V; Lalic H; Tomic B; Smoljo T; Batinic J; Dubravcic K; Batinic D; Bedalov A; Visnjic D
    Int J Hematol; 2022 Jan; 115(1):43-53. PubMed ID: 34546543
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Brg1 mutation alters oxidative stress responses in glioblastoma.
    Gowda P; Lathoria K; Umdor SB; Sen E
    Neurochem Int; 2021 Nov; 150():105189. PubMed ID: 34543701
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Alcohol-abuse drug disulfiram targets pediatric glioma via mll degradation.
    Meier S; Cantilena S; Niklison Chirou MV; Anderson J; Hargrave D; Salomoni P; de Boer J; Michod D
    Cell Death Dis; 2021 Aug; 12(8):785. PubMed ID: 34381018
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Matrix stiffness epigenetically regulates the oncogenic activation of the Yes-associated protein in gastric cancer.
    Jang M; An J; Oh SW; Lim JY; Kim J; Choi JK; Cheong JH; Kim P
    Nat Biomed Eng; 2021 Jan; 5(1):114-123. PubMed ID: 33288878
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
    Chang S; Yim S; Park H
    Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. C-terminal BRE inhibits cellular proliferation and increases sensitivity to chemotherapeutic drugs of mll-AF9 acute myeloid leukemia cells.
    Pun CC; Lee KK; Chui YL
    Leuk Lymphoma; 2019 Dec; 60(12):3011-3019. PubMed ID: 31111759
    [TBL] [Abstract] [Full Text] [Related]  


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