Terms: = Brain cancer AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1
86 results:
1. Simulated microgravity induces DNA damage concurrent with impairment of DNA repair and activation of cell-type specific DNA damage response in microglial and glioblastoma cells.
Singh R; Jaiswal A; Singh RP
Biochim Biophys Acta Mol Cell Res; 2024 Mar; 1871(3):119679. PubMed ID: 38272357
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2. KRAS is a molecular determinant of platinum responsiveness in glioblastoma.
Zuchegna C; Leone S; Romano A; Porcellini A; Messina S
BMC Cancer; 2024 Jan; 24(1):77. PubMed ID: 38225605
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3. Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models.
Dyshlovoy SA; Hauschild J; Venz S; Krisp C; Kolbe K; Zapf S; Heinemann S; Fita KD; Shubina LK; Makarieva TN; Guzii AG; Rohlfing T; Kaune M; Busenbender T; Mair T; Moritz M; Poverennaya EV; Schlüter H; Serdyuk V; Stonik VA; Dierlamm J; Bokemeyer C; Mohme M; Westphal M; Lamszus K; von Amsberg G; Maire CL
Mol Pharm; 2023 Oct; 20(10):4994-5005. PubMed ID: 37733943
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4. Quantitative profiling of genes associated with cancer pathways in brain tumors.
Majerčíková Z; Dibdiaková K; Galanda M; Galanda T; Richterová R; Kolarovszki B; Račay P; Hatok J
Klin Onkol; 2023; 36(3):224-233. PubMed ID: 37353350
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5. Molecular and clinicopathologic characterization of pediatric histiocytoses.
Hélias-Rodzewicz Z; Donadieu J; Terrones N; Barkaoui MA; Lambilliotte A; Moshous D; Thomas C; Azarnoush S; Pasquet M; Mansuy L; Aladjidi N; Jeziorski E; Marec-Berard P; Gilibert-Yvert M; Spiegel A; Saultier P; Pellier I; Pagnier A; Pertuisel S; Poiree M; Bodet D; Millot F; Isfan F; Stephan JL; Leruste A; Rigaud C; Filhon B; Carausu L; Reguerre Y; Kieffer I; Brichard B; Ben Jannet R; Bakari M; Idbaih A; Bodemer C; Cohen-Aubart F; Haroche J; Tazi A; Boudjemaa S; Fraitag S; Emile JF; Heritier S;
Am J Hematol; 2023 Jul; 98(7):1058-1069. PubMed ID: 37115038
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6. Dabrafenib, alone or in combination with trametinib, in BRAF V600-mutated pediatric Langerhans cell histiocytosis.
Whitlock JA; Geoerger B; Dunkel IJ; Roughton M; Choi J; Osterloh L; Russo M; Hargrave D
Blood Adv; 2023 Aug; 7(15):3806-3815. PubMed ID: 36884302
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7. An integrated genetic analysis of epileptogenic brain malformed lesions.
Fujita A; Kato M; Sugano H; Iimura Y; Suzuki H; Tohyama J; Fukuda M; Ito Y; Baba S; Okanishi T; Enoki H; Fujimoto A; Yamamoto A; Kawamura K; Kato S; Honda R; Ono T; Shiraishi H; Egawa K; Shirai K; Yamamoto S; Hayakawa I; Kawawaki H; Saida K; Tsuchida N; Uchiyama Y; Hamanaka K; Miyatake S; Mizuguchi T; Nakashima M; Saitsu H; Miyake N; Kakita A; Matsumoto N
Acta Neuropathol Commun; 2023 Mar; 11(1):33. PubMed ID: 36864519
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8. Immune landscape-based machine-learning-assisted subclassification, prognosis, and immunotherapy prediction for glioblastoma.
Li H; He J; Li M; Li K; Pu X; Guo Y
Front Immunol; 2022; 13():1027631. PubMed ID: 36532035
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9. Variation in human water turnover associated with environmental and lifestyle factors.
Yamada Y; Zhang X; Henderson MET; Sagayama H; Pontzer H; Watanabe D; Yoshida T; Kimura M; Ainslie PN; Andersen LF; Anderson LJ; Arab L; Baddou I; Bedu-Addo K; Blaak EE; Blanc S; Bonomi AG; Bouten CVC; Bovet P; Buchowski MS; Butte NF; Camps SG; Close GL; Cooper JA; Cooper R; Das SK; Dugas LR; Eaton S; Ekelund U; Entringer S; Forrester T; Fudge BW; Goris AH; Gurven M; Halsey LG; Hambly C; El Hamdouchi A; Hoos MB; Hu S; Joonas N; Joosen AM; Katzmarzyk P; Kempen KP; Kraus WE; Kriengsinyos W; Kushner RF; Lambert EV; Leonard WR; Lessan N; Martin CK; Medin AC; Meijer EP; Morehen JC; Morton JP; Neuhouser ML; Nicklas TA; Ojiambo RM; Pietiläinen KH; Pitsiladis YP; Plange-Rhule J; Plasqui G; Prentice RL; Rabinovich RA; Racette SB; Raichlen DA; Ravussin E; Redman LM; Reilly JJ; Reynolds RM; Roberts SB; Schuit AJ; Sardinha LB; Silva AM; Sjödin AM; Stice E; Urlacher SS; Valenti G; Van Etten LM; Van Mil EA; Wells JCK; Wilson G; Wood BM; Yanovski JA; Murphy-Alford AJ; Loechl CU; Luke AH; Rood J; Westerterp KR; Wong WW; Miyachi M; Schoeller DA; Speakman JR;
Science; 2022 Nov; 378(6622):909-915. PubMed ID: 36423296
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10. Emerging glioneuronal and neuronal tumors: case-based review.
Lim SD; Kim SI; Park JW; Won JK; Kim SK; Phi JH; Chung CK; Choi SH; Yun H; Park SH
Brain Tumor Pathol; 2022 Apr; 39(2):65-78. PubMed ID: 35048219
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11. DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition.
Izquierdo E; Carvalho DM; Mackay A; Temelso S; Boult JKR; Pericoli G; Fernandez E; Das M; Molinari V; Grabovska Y; Rogers RF; Ajmone-Cat MA; Proszek PZ; Stubbs M; Depani S; O'Hare P; Yu L; Roumelioti G; Choudhary JS; Clarke M; Fairchild AR; Jacques TS; Grundy RG; Howell L; Picton S; Adamski J; Wilson S; Gray JC; Zebian B; Marshall LV; Carceller F; Grill J; Vinci M; Robinson SP; Hubank M; Hargrave D; Jones C
Cancer Discov; 2022 Mar; 12(3):712-729. PubMed ID: 34737188
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12. Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAF
Schreck KC; Morin A; Zhao G; Allen AN; Flannery P; Glantz M; Green AL; Jones C; Jones KL; Kilburn LB; Nazemi KJ; Samuel D; Sanford B; Solomon DA; Wang J; Pratilas CA; Nicolaides T; Mulcahy Levy JM
Clin Cancer Res; 2021 Nov; 27(22):6197-6208. PubMed ID: 34433654
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13. Novel Pathways and Mechanisms of Nicotine-Induced Oral Carcinogenesis.
Sharma M; Shetty SS; Radhakrishnan RA
Recent Pat Anticancer Drug Discov; 2022; 17(1):66-79. PubMed ID: 34365933
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14. miR-424 induces apoptosis in glioblastoma cells and targets AKT1 and RAF1 oncogenes from the ERBB signaling pathway.
Gheidari F; Arefian E; Adegani FJ; Kalhori MR; Seyedjafari E; Kabiri M; Teimoori-Toolabi L; Soleimani M
Eur J Pharmacol; 2021 Sep; 906():174273. PubMed ID: 34153339
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15. Response to BRAF and mek1/2 inhibition in a young adult with BRAF V600E mutant epithelioid glioblastoma multiforme: A Case Report and Literature Review.
Venkatesh A; Joshi A; Allinson K; Das T; Santarius T; Jefferies SJ; Harris FP; Jena R; Doherty GJ
Curr Probl Cancer; 2021 Oct; 45(5):100701. PubMed ID: 33461766
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16. EIF4A3-induced circular RNA ASAP1 promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/mek1/ERK1-2 signaling.
Wei Y; Lu C; Zhou P; Zhao L; Lyu X; Yin J; Shi Z; You Y
Neuro Oncol; 2021 Apr; 23(4):611-624. PubMed ID: 32926734
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17. MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors.
Shahab S; Rubens J; Kaur H; Sweeney H; Eberhart CG; Raabe EH
J Neuropathol Exp Neurol; 2020 Jul; 79(7):746-753. PubMed ID: 32472116
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18. Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Feng X; Zhang H; Meng L; Song H; Zhou Q; Qu C; Zhao P; Li Q; Zou C; Liu X; Zhang Z
Autophagy; 2021 Mar; 17(3):723-742. PubMed ID: 32186433
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19. Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Fortin J; Tian R; Zarrabi I; Hill G; Williams E; Sanchez-Duffhues G; Thorikay M; Ramachandran P; Siddaway R; Wong JF; Wu A; Apuzzo LN; Haight J; You-Ten A; Snow BE; Wakeham A; Goldhamer DJ; Schramek D; Bullock AN; Dijke PT; Hawkins C; Mak TW
Cancer Cell; 2020 Mar; 37(3):308-323.e12. PubMed ID: 32142668
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20. Preclinical evaluation of binimetinib (mek162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma.
Bikhezar F; de Kruijff RM; van der Meer AJGM; Torrelo Villa G; van der Pol SMA; Becerril Aragon G; Gasol Garcia A; Narayan RS; de Vries HE; Slotman BJ; Denkova AG; Sminia P
J Neurooncol; 2020 Jan; 146(2):239-246. PubMed ID: 31875307
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