BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND MLH1, COCA2, 4292, ENSG00000076242, hMLH1, FCC2, HNPCC2, P40692, MGC5172, HNPCC AND Prognosis
33 results:

  • 1. Exploring the combined anti-cancer effects of sodium butyrate and celastrol in glioblastoma cell lines: a novel therapeutic approach.
    Kartal B; Denizler-Ebiri FN; Güven M; Taşpınar F; Canpınar H; Çetin S; Karaduman T; Küççüktürk S; Castresana J; Taşpınar M
    Med Oncol; 2024 Mar; 41(5):97. PubMed ID: 38532150
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Mismatch Repair Deficiency as a Predictive and Prognostic Biomarker in Endometrial cancer: A Review on Immunohistochemistry Staining Patterns and Clinical Implications.
    Addante F; d'Amati A; Santoro A; Angelico G; Inzani F; Arciuolo D; Travaglino A; Raffone A; D'Alessandris N; Scaglione G; Valente M; Tinnirello G; Sfregola S; Padial Urtueta B; Piermattei A; Cianfrini F; Mulè A; Bragantini E; Zannoni GF
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38256131
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Mismatch Repair Deficiency in Biliary Tract cancer: Prognostic Implications and Correlation with Histology.
    Vivaldi C; Genovesi V; Ugolini C; Bernardini L; Casadei-Gardini A; Formica V; Salani F; Orsi G; Massa V; Cacciato-Insilla A; Caccese M; Cesario S; Andrikou K; Graziani J; Campani D; Vasile E; Fontanini G; Fornaro L; Masi G
    Oncology; 2024; 102(2):157-167. PubMed ID: 37699372
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Deficient mismatch repair/microsatellite unstable colorectal cancer: Diagnosis, prognosis and treatment.
    Taieb J; Svrcek M; Cohen R; Basile D; Tougeron D; Phelip JM
    Eur J Cancer; 2022 Nov; 175():136-157. PubMed ID: 36115290
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Complete Response of a Patient With a Mismatch Repair Deficient Aggressive Pituitary Adenoma to Immune Checkpoint Inhibitor Therapy: A Case Report.
    Shah S; Manzoor S; Rothman Y; Hagen M; Pater L; Golnik K; Mahammedi A; Lin AL; Bhabhra R; Forbes JA; Sengupta S
    Neurosurgery; 2022 Aug; 91(2):e51-e56. PubMed ID: 35544035
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Mismatch repair proteins PMS2 and mlh1 can further refine molecular stratification of IDH-mutant lower grade astrocytomas.
    Yang RR; Li KK; Zhang ZY; Chan AK; Wang WW; Chan DT; Li WC; Liu XZ; Li FC; Chen H; Ng HK; Mao Y; Shi ZF
    Clin Neurol Neurosurg; 2021 Sep; 208():106882. PubMed ID: 34428613
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Mismatch repair-deficient prostate cancer with parenchymal brain metastases treated with immune checkpoint blockade.
    Sena LA; Salles DC; Engle EL; Zhu Q; Tukachinsky H; Lotan TL; Antonarakis ES
    Cold Spring Harb Mol Case Stud; 2021 Aug; 7(4):. PubMed ID: 34140335
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Assessment of mismatch repair deficiency, CDX2, beta-catenin and E-cadherin expression in colon cancer: molecular characteristics and impact on prognosis and survival - an immunohistochemical study.
    Melincovici CS; Boşca AB; Şuşman S; Cutaş A; Mărginean M; Ilea A; Moldovan IM; Jianu EM; Neag MA; Bulboacă AE; Mihu CM
    Rom J Morphol Embryol; 2020; 61(3):715-727. PubMed ID: 33817713
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Prevalence and prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial cancer.
    Post CCB; Stelloo E; Smit VTHBM; Ruano D; Tops CM; Vermij L; Rutten TA; Jürgenliemk-Schulz IM; Lutgens LCHW; Jobsen JJ; Nout RA; Crosbie EJ; Powell ME; Mileshkin L; Leary A; Bessette P; Putter H; de Boer SM; Horeweg N; Nielsen M; Wezel TV; Bosse T; Creutzberg CL
    J Natl Cancer Inst; 2021 Sep; 113(9):1212-1220. PubMed ID: 33693762
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Prognostic Value and Immunohistochemical Analysis of Mismatch Repair Deficiency in Patients with Stage II and III Colorectal Carcinoma-A Single-Center Study.
    Denčić T; Krstić M; Petrović A; Jovičić-Milentijević M; Radenković G; Jović M; Živković N; Šalinger-Martinović S; Branković B; Stojanović S
    Medicina (Kaunas); 2020 Dec; 56(12):. PubMed ID: 33302424
    [No Abstract]    [Full Text] [Related]  

  • 11. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
    Suwala AK; Stichel D; Schrimpf D; Kloor M; Wefers AK; Reinhardt A; Maas SLN; Kratz CP; Schweizer L; Hasselblatt M; Snuderl M; Abedalthagafi MSJ; Abdullaev Z; Monoranu CM; Bergmann M; Pekrun A; Freyschlag C; Aronica E; Kramm CM; Hinz F; Sievers P; Korshunov A; Kool M; Pfister SM; Sturm D; Jones DTW; Wick W; Unterberg A; Hartmann C; Dodgshun A; Tabori U; Wesseling P; Sahm F; von Deimling A; Reuss DE
    Acta Neuropathol; 2021 Jan; 141(1):85-100. PubMed ID: 33216206
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. PD‑L1 and IDO‑1 expression in undifferentiated pleomorphic sarcoma: The associations with tumor infiltrating lymphocytes, dMMR and HLA class I.
    Ishihara S; Yamada Y; Iwasaki T; Yoshimoto M; Toda Y; Kohashi K; Yamamoto H; Matsumoto Y; Nakashima Y; Oda Y
    Oncol Rep; 2021 Jan; 45(1):379-389. PubMed ID: 33155664
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Colorectal cancer with invasive micropapillary components (IMPCs) shows high lymph node metastasis and a poor prognosis: A retrospective clinical study.
    Guo Z; Yang Z; Li D; Tang J; Xu J; Shen H; Yuan Y
    Medicine (Baltimore); 2020 May; 99(21):e20238. PubMed ID: 32481300
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Frequency of mismatch repair deficiency in pancreatic ductal adenocarcinoma.
    Ahmad-Nielsen SA; Bruun Nielsen MF; Mortensen MB; Detlefsen S
    Pathol Res Pract; 2020 Jun; 216(6):152985. PubMed ID: 32360245
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Microsatellite Instability in Glioblastoma: Is It Really Relevant in Tumor prognosis?
    Tepeoglu M; Borcek P; Ozen O; Altinors N
    Turk Neurosurg; 2019; 29(5):778-784. PubMed ID: 31529454
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.
    Dominguez-Valentin M; Sampson JR; Seppälä TT; Ten Broeke SW; Plazzer JP; Nakken S; Engel C; Aretz S; Jenkins MA; Sunde L; Bernstein I; Capella G; Balaguer F; Thomas H; Evans DG; Burn J; Greenblatt M; Hovig E; de Vos Tot Nederveen Cappel WH; Sijmons RH; Bertario L; Tibiletti MG; Cavestro GM; Lindblom A; Della Valle A; Lopez-Köstner F; Gluck N; Katz LH; Heinimann K; Vaccaro CA; Büttner R; Görgens H; Holinski-Feder E; Morak M; Holzapfel S; Hüneburg R; Knebel Doeberitz MV; Loeffler M; Rahner N; Schackert HK; Steinke-Lange V; Schmiegel W; Vangala D; Pylvänäinen K; Renkonen-Sinisalo L; Hopper JL; Win AK; Haile RW; Lindor NM; Gallinger S; Le Marchand L; Newcomb PA; Figueiredo JC; Thibodeau SN; Wadt K; Therkildsen C; Okkels H; Ketabi Z; Moreira L; Sánchez A; Serra-Burriel M; Pineda M; Navarro M; Blanco I; Green K; Lalloo F; Crosbie EJ; Hill J; Denton OG; Frayling IM; Rødland EA; Vasen H; Mints M; Neffa F; Esperon P; Alvarez K; Kariv R; Rosner G; Pinero TA; Gonzalez ML; Kalfayan P; Tjandra D; Winship IM; Macrae F; Möslein G; Mecklin JP; Nielsen M; Møller P
    Genet Med; 2020 Jan; 22(1):15-25. PubMed ID: 31337882
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Prevalence of recurrent oncogenic fusion in mismatch repair-deficient colorectal carcinoma with hypermethylated mlh1 and wild-type BRAF and KRAS.
    Wang J; Yi Y; Xiao Y; Dong L; Liang L; Teng L; Ying JM; Lu T; Liu Y; Guan Y; Pang J; Zhou L; Lu J; Zhang Z; Liu X; Liang X; Zeng X; Yi X; Zhou W; Xia X; Yang L; Zhang J; Kopetz S; Futreal PA; Wu H; Liang Z
    Mod Pathol; 2019 Jul; 32(7):1053-1064. PubMed ID: 30723297
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. DNA mismatch repair deficiency but not ARID1A loss is associated with prognosis in small intestinal adenocarcinoma.
    González I; Goyal B; Xia MD; Pai RK; Ma C
    Hum Pathol; 2019 Mar; 85():18-26. PubMed ID: 30381262
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Epigenetic changes underlie the aggressiveness of histologically benign meningiomas that recur.
    San-Miguel T; Navarro L; Megías J; Muñoz-Hidalgo L; Gil-Benso R; Roldán P; López-Ginés C; Cerdá-Nicolás M
    Hum Pathol; 2019 Feb; 84():105-114. PubMed ID: 30261191
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Durable Response to Nivolumab in a Pediatric Patient with Refractory Glioblastoma and Constitutional Biallelic Mismatch Repair Deficiency.
    AlHarbi M; Ali Mobark N; AlMubarak L; Aljelaify R; AlSaeed M; Almutairi A; Alqubaishi F; Hussain ME; Balbaid AAO; Said Marie A; AlSubaie L; AlShieban S; alTassan N; Ramkissoon SH; Abedalthagafi M
    Oncologist; 2018 Dec; 23(12):1401-1406. PubMed ID: 30104292
    [TBL] [Abstract] [Full Text] [Related]  


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