BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND MYCN, N-myc, 4613, ENSG00000134323, NMYC, MODED, ODED AND Clinical Outcome
17 results:

  • 1. Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas.
    Pohl LC; Leitheiser M; Obrecht D; Schweizer L; Wefers AK; Eckhardt A; Raffeld M; Sturm D; Pajtler KW; Rutkowski S; Fukuoka K; Ichimura K; Bockmayr M; Schüller U
    Acta Neuropathol; 2024 Jan; 147(1):24. PubMed ID: 38265522
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond.
    Kresbach C; Neyazi S; Schüller U
    Brain Pathol; 2022 Jul; 32(4):e13068. PubMed ID: 35307892
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Steroid receptor-associated and regulated protein is a biomarker in predicting the clinical outcome and treatment response in malignancies.
    Naderi A
    Cancer Rep (Hoboken); 2020 Oct; 3(5):e1267. PubMed ID: 32706923
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Expression of GNAS, TP53, and PTEN Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup.
    da Silva LS; Mançano BM; de Paula FE; Dos Reis MB; de Almeida GC; Matsushita M; Junior CA; Evangelista AF; Saggioro F; Serafini LN; Stavale JN; Malheiros SMF; Lima M; Hajj GNM; de Lima MA; Taylor MD; Leal LF; Reis RM
    J Mol Diagn; 2020 Jul; 22(7):957-966. PubMed ID: 32380172
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. mycn amplification drives an aggressive form of spinal ependymoma.
    Ghasemi DR; Sill M; Okonechnikov K; Korshunov A; Yip S; Schutz PW; Scheie D; Kruse A; Harter PN; Kastelan M; Wagner M; Hartmann C; Benzel J; Maass KK; Khasraw M; Sträter R; Thomas C; Paulus W; Kratz CP; Witt H; Kawauchi D; Herold-Mende C; Sahm F; Brandner S; Kool M; Jones DTW; von Deimling A; Pfister SM; Reuss DE; Pajtler KW
    Acta Neuropathol; 2019 Dec; 138(6):1075-1089. PubMed ID: 31414211
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Medulloblastoma, WNT-activated/SHH-activated: clinical impact of molecular analysis and histogenetic evaluation.
    Cambruzzi E
    Childs Nerv Syst; 2018 May; 34(5):809-815. PubMed ID: 29582169
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Molecular and in vivo characterization of cancer-propagating cells derived from mycn-dependent medulloblastoma.
    Ahmad Z; Jasnos L; Gil V; Howell L; Hallsworth A; Petrie K; Sawado T; Chesler L
    PLoS One; 2015; 10(3):e0119834. PubMed ID: 25785590
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. High expression of n-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma.
    Meng D; Chen Y; Yun D; Zhao Y; Wang J; Xu T; Li X; Wang Y; Yuan L; Sun R; Song X; Huai C; Hu L; Yang S; Min T; Chen J; Chen H; Lu D
    Oncotarget; 2015 Mar; 6(7):4901-19. PubMed ID: 25669971
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Biological and clinical heterogeneity of mycn-amplified medulloblastoma.
    Korshunov A; Remke M; Kool M; Hielscher T; Northcott PA; Williamson D; Pfaff E; Witt H; Jones DT; Ryzhova M; Cho YJ; Wittmann A; Benner A; Weiss WA; von Deimling A; Scheurlen W; Kulozik AE; Clifford SC; Peter Collins V; Westermann F; Taylor MD; Lichter P; Pfister SM
    Acta Neuropathol; 2012 Apr; 123(4):515-27. PubMed ID: 22160402
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The coamplification pattern of the mycn amplicon is an invariable attribute of most mycn-amplified human neuroblastomas.
    Weber A; Starke S; Bergmann E; Christiansen H
    Clin Cancer Res; 2006 Dec; 12(24):7316-21. PubMed ID: 17189403
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. brain-derived neurotrophic factor activation of TrkB induces vascular endothelial growth factor expression via hypoxia-inducible factor-1alpha in neuroblastoma cells.
    Nakamura K; Martin KC; Jackson JK; Beppu K; Woo CW; Thiele CJ
    Cancer Res; 2006 Apr; 66(8):4249-55. PubMed ID: 16618748
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Prognosis-related molecular markers in pediatric central nervous system tumors.
    Rickert CH
    J Neuropathol Exp Neurol; 2004 Dec; 63(12):1211-24. PubMed ID: 15624758
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Full-length telomerase reverse transcriptase messenger RNA is an independent prognostic factor in neuroblastoma.
    Krams M; Hero B; Berthold F; Parwaresch R; Harms D; Rudolph P
    Am J Pathol; 2003 Mar; 162(3):1019-26. PubMed ID: 12598334
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Genetic alterations in childhood medulloblastoma analyzed by comparative genomic hybridization.
    Michiels EM; Weiss MM; Hoovers JM; Baak JP; Voûte PA; Baas F; Hermsen MA
    J Pediatr Hematol Oncol; 2002; 24(3):205-10. PubMed ID: 11990307
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Quantitative determination of sst2 gene expression in neuroblastoma tumor predicts patient outcome.
    Raggi CC; Maggi M; Renzi D; Calabrò A; Bagnoni ML; Scaruffi P; Tonini GP; Pazzagli M; De Bernardi B; Bernini G; Serio M; Orlando C
    J Clin Endocrinol Metab; 2000 Oct; 85(10):3866-73. PubMed ID: 11061551
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Expression of neuronal src mRNA as a favorable marker and inverse correlation to n-myc gene amplification in human neuroblastomas.
    Matsunaga T; Shirasawa H; Tanabe M; Ohnuma N; Kawamura K; Etoh T; Takahashi H; Simizu B
    Int J Cancer; 1994 Sep; 58(6):793-8. PubMed ID: 7523310
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Detection of n-myc oncogene expression in human neuroblastoma by in situ hybridization and blot analysis: relationship to clinical outcome.
    Grady-Leopardi EF; Schwab M; Ablin AR; Rosenau W
    Cancer Res; 1986 Jun; 46(6):3196-9. PubMed ID: 2421891
    [TBL] [Abstract] [Full Text] [Related]  


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