BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND NFE2L2, ENSG00000116044, 4780, Q16236, NRF2
166 results:

  • 1. Orexin-A mediates glioblastoma proliferation inhibition by increasing ferroptosis triggered by unstable iron pools and GPX4 depletion.
    Huan R; Zhang J; Yue J; Yang S; Han G; Cheng Y; Tan Y
    J Cell Mol Med; 2024 May; 28(9):e18318. PubMed ID: 38685674
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Therapeutic potential of targeting nrf2 by panobinostat in pituitary neuroendocrine tumors.
    Cheng Y; Dai Y; Tang H; Lu X; Xie J; Xie W; Zhang Q; Liu Y; Lin S; Yao H; Shang H; Yang K; Liu H; Wu X; Zhang J; Zhang X; Xue L; Wu ZB
    Acta Neuropathol Commun; 2024 Apr; 12(1):61. PubMed ID: 38637883
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Borax induces ferroptosis of glioblastoma by targeting HSPA5/nrf2/GPx4/GSH pathways.
    Tuncer C; Hacioglu C
    J Cell Mol Med; 2024 Apr; 28(7):e18206. PubMed ID: 38494858
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of nrf2 modulators for the treatment of glioblastoma multiforme.
    Yang H; Song P; Li B; Li S; Yang J
    Bioorg Med Chem; 2024 Apr; 103():117684. PubMed ID: 38493731
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma.
    Singh S; Lathoria K; Umdor SB; Singh J; Suri V; Sen E
    Cytokine; 2024 Apr; 176():156535. PubMed ID: 38325141
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma.
    Li Y; Yang C; Xie L; Shi F; Tang M; Luo X; Liu N; Hu X; Zhu Y; Bode AM; Gao Q; Zhou J; Fan J; Li X; Cao Y
    Cell Death Dis; 2024 Jan; 15(1):95. PubMed ID: 38287022
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Role of Natural Compounds Modulating Heme Catabolic Pathway in Gut, Liver, Cardiovascular, and brain Diseases.
    Jayanti S; Vitek L; Verde CD; Llido JP; Sukowati C; Tiribelli C; Gazzin S
    Biomolecules; 2024 Jan; 14(1):. PubMed ID: 38254662
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The effect of p53 on the activity of nrf2 and NDRG2 genes through apoptotic pathway in IDH-wildtype glioblastoma.
    Kurdi M; Baeesa S; Fadul MM; Alkhotani A; Alkhayyat S; Karami MM; Alsinani T; Katib Y; Fathaddin AA; Faizo E; Lary AI; Almansouri M; Maghrabi Y; Alyousef MA; Addass B
    Pathol Res Pract; 2024 Feb; 254():155118. PubMed ID: 38241776
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. SLC38A5 Modulates Ferroptosis to Overcome Gemcitabine Resistance in Pancreatic cancer.
    Kim MJ; Kim HS; Kang HW; Lee DE; Hong WC; Kim JH; Kim M; Cheong JH; Kim HJ; Park JS
    Cells; 2023 Oct; 12(20):. PubMed ID: 37887353
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. nrf2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma.
    Cirotti C; Taddei I; Contadini C; Di Girolamo C; Pepe G; De Bardi M; Borsellino G; Helmer-Citterich M; Barilà D
    Life Sci Alliance; 2024 Jan; 7(1):. PubMed ID: 37879937
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The preventive effects of broccoli bioactives against cancer: Evidence from a validated rat glioma model.
    Baenas N; Vega-García A; Manjarrez-Marmolejo J; Moreno DA; Feria-Romero IA
    Biomed Pharmacother; 2023 Dec; 168():115720. PubMed ID: 37839110
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Licochalcone A: A Potential Multitarget Drug for Alzheimer's Disease Treatment.
    Olloquequi J; Ettcheto M; Cano A; Fortuna A; Bicker J; Sánchez-Lopez E; Paz C; Ureña J; Verdaguer E; Auladell C; Camins A
    Int J Mol Sci; 2023 Sep; 24(18):. PubMed ID: 37762479
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome.
    Yang YH; Li W; Ren LW; Yang H; Zhang YZ; Zhang S; Hao Y; Yu DK; Tong RS; Du GH; Shi JY; Wang JH
    Acta Pharmacol Sin; 2024 Jan; 45(1):209-222. PubMed ID: 37749236
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A partial agonist of PPARγ prevents paclitaxel-induced peripheral neuropathy in mice, by inhibiting neuroinflammation.
    Benvenutti L; Wolff FR; Corrêa TP; Melato J; Goldoni FC; De Faveri R; Patel YBK; de Souza JA; Grockoski HA; Nilz PM; Bombardelli CL; Remor AP; Varela KG; Costa NTC; Hernandes MZ; Lacerda MG; Rodrigues KD; Milton FA; Neves FAR; Pereira MES; Kormann Imianowsky EC; de Campos Buzzi F; Brunaldi Marutani VH; Stoeberl LC; Correa R; Eller S; de Oliveira TF; Gonçalves TBP; da Silva RC; Passos GF; da Costa R; Santin JR; Quintão NLM
    Br J Pharmacol; 2024 Apr; 181(7):1128-1149. PubMed ID: 37721089
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. nrf2 Signaling Pathway: a Potential Therapeutic Target in Combating Oxidative Stress and Neurotoxicity in Chemotherapy-Induced Cognitive Impairment.
    Lal R; Dharavath RN; Chopra K
    Mol Neurobiol; 2024 Feb; 61(2):593-608. PubMed ID: 37644279
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in nrf2-dependent and -independent manner.
    Kim JW; Kim MJ; Han TH; Lee JY; Kim S; Kim H; Oh KJ; Kim WK; Han BS; Bae KH; Ban HS; Bae SH; Lee SC; Lee H; Lee EW
    Cell Death Dis; 2023 Aug; 14(8):567. PubMed ID: 37633973
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The Role of CDK20 Protein in Carcinogenesis.
    Chivukula S; Malkhed V
    Curr Drug Targets; 2023; 24(10):790-796. PubMed ID: 37469151
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.
    Ikeda R; Noshiro D; Morishita H; Takada S; Kageyama S; Fujioka Y; Funakoshi T; Komatsu-Hirota S; Arai R; Ryzhii E; Abe M; Koga T; Motohashi H; Nakao M; Sakimura K; Horii A; Waguri S; Ichimura Y; Noda NN; Komatsu M
    EMBO J; 2023 Jul; 42(14):e113349. PubMed ID: 37306101
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
    Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
    Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via nrf2/SOD2 Modulation.
    Su IC; Su YK; Setiawan SA; Yadav VK; Fong IH; Yeh CT; Lin CM; Liu HW
    Int J Mol Sci; 2023 Apr; 24(9):. PubMed ID: 37175412
    [TBL] [Abstract] [Full Text] [Related]  


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