BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND NFE2L2, ENSG00000116044, 4780, Q16236, NRF2 AND Treatment
73 results:

  • 1. Orexin-A mediates glioblastoma proliferation inhibition by increasing ferroptosis triggered by unstable iron pools and GPX4 depletion.
    Huan R; Zhang J; Yue J; Yang S; Han G; Cheng Y; Tan Y
    J Cell Mol Med; 2024 May; 28(9):e18318. PubMed ID: 38685674
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Therapeutic potential of targeting nrf2 by panobinostat in pituitary neuroendocrine tumors.
    Cheng Y; Dai Y; Tang H; Lu X; Xie J; Xie W; Zhang Q; Liu Y; Lin S; Yao H; Shang H; Yang K; Liu H; Wu X; Zhang J; Zhang X; Xue L; Wu ZB
    Acta Neuropathol Commun; 2024 Apr; 12(1):61. PubMed ID: 38637883
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Borax induces ferroptosis of glioblastoma by targeting HSPA5/nrf2/GPx4/GSH pathways.
    Tuncer C; Hacioglu C
    J Cell Mol Med; 2024 Apr; 28(7):e18206. PubMed ID: 38494858
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of nrf2 modulators for the treatment of glioblastoma multiforme.
    Yang H; Song P; Li B; Li S; Yang J
    Bioorg Med Chem; 2024 Apr; 103():117684. PubMed ID: 38493731
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma.
    Singh S; Lathoria K; Umdor SB; Singh J; Suri V; Sen E
    Cytokine; 2024 Apr; 176():156535. PubMed ID: 38325141
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma.
    Li Y; Yang C; Xie L; Shi F; Tang M; Luo X; Liu N; Hu X; Zhu Y; Bode AM; Gao Q; Zhou J; Fan J; Li X; Cao Y
    Cell Death Dis; 2024 Jan; 15(1):95. PubMed ID: 38287022
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. SLC38A5 Modulates Ferroptosis to Overcome Gemcitabine Resistance in Pancreatic cancer.
    Kim MJ; Kim HS; Kang HW; Lee DE; Hong WC; Kim JH; Kim M; Cheong JH; Kim HJ; Park JS
    Cells; 2023 Oct; 12(20):. PubMed ID: 37887353
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Licochalcone A: A Potential Multitarget Drug for Alzheimer's Disease treatment.
    Olloquequi J; Ettcheto M; Cano A; Fortuna A; Bicker J; Sánchez-Lopez E; Paz C; Ureña J; Verdaguer E; Auladell C; Camins A
    Int J Mol Sci; 2023 Sep; 24(18):. PubMed ID: 37762479
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome.
    Yang YH; Li W; Ren LW; Yang H; Zhang YZ; Zhang S; Hao Y; Yu DK; Tong RS; Du GH; Shi JY; Wang JH
    Acta Pharmacol Sin; 2024 Jan; 45(1):209-222. PubMed ID: 37749236
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. nrf2 Signaling Pathway: a Potential Therapeutic Target in Combating Oxidative Stress and Neurotoxicity in Chemotherapy-Induced Cognitive Impairment.
    Lal R; Dharavath RN; Chopra K
    Mol Neurobiol; 2024 Feb; 61(2):593-608. PubMed ID: 37644279
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
    Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
    Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via nrf2/SOD2 Modulation.
    Su IC; Su YK; Setiawan SA; Yadav VK; Fong IH; Yeh CT; Lin CM; Liu HW
    Int J Mol Sci; 2023 Apr; 24(9):. PubMed ID: 37175412
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
    Liang C; Yi K; Zhou X; Li X; Zhong C; Cao H; Xie C; Zhu J
    Phytother Res; 2023 Jul; 37(7):2995-3008. PubMed ID: 36866538
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Identification of a copper metabolism-related gene signature for predicting prognosis and immune response in glioma.
    Li L; Leng W; Chen J; Li S; Lei B; Zhang H; Zhao H
    Cancer Med; 2023 Apr; 12(8):10123-10137. PubMed ID: 36856182
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. CircOMA1 modulates cabergoline resistance by downregulating ferroptosis in prolactinoma.
    Wu N; Zhu D; Li J; Li X; Zhu Z; Rao Q; Hu B; Wang H; Zhu Y
    J Endocrinol Invest; 2023 Aug; 46(8):1573-1587. PubMed ID: 36853491
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via nrf2.
    Liu Y; Chou FJ; Lang F; Zhang M; Song H; Zhang W; Davis DL; Briceno NJ; Zhang Y; Cimino PJ; Zaghloul KA; Gilbert MR; Armstrong TS; Yang C
    Clin Cancer Res; 2023 Apr; 29(7):1305-1316. PubMed ID: 36648507
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.
    Linke F; Johnson JEC; Kern S; Bennett CD; Lourdusamy A; Lea D; Clifford SC; Merry CLR; Stolnik S; Alexander MR; Peet AC; Scurr DJ; Griffiths RL; Grabowska AM; Kerr ID; Coyle B
    Acta Neuropathol Commun; 2023 Jan; 11(1):6. PubMed ID: 36631900
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Baicalin lipid nanocapsules for treatment of glioma: characterization, mechanistic cytotoxicity, and pharmacokinetic evaluation.
    Ibrahim A; Abdel Gaber SA; Fawzi Kabil M; Ahmed-Farid OAH; Hirsch AKH; El-Sherbiny IM; Nasr M
    Expert Opin Drug Deliv; 2022 Nov; 19(11):1549-1560. PubMed ID: 36287914
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Hypoxia-Driven M2-Polarized Macrophages Facilitate cancer Aggressiveness and Temozolomide Resistance in Glioblastoma.
    Zhang G; Tao X; Ji B; Gong J
    Oxid Med Cell Longev; 2022; 2022():1614336. PubMed ID: 36046687
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Machine learning for the micropeptide encoded by LINC02381 regulates ferroptosis through the glucose transporter SLC2A10 in glioblastoma.
    Jiang L; Yang J; Xu Q; Lv K; Cao Y
    BMC Cancer; 2022 Aug; 22(1):882. PubMed ID: 35962317
    [TBL] [Abstract] [Full Text] [Related]  


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