BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND NT5C2, ENSG00000076685, 22978, P49902, PNT5, NT5B, GMP, cN-II
43 results:

  • 1. Successful expansion and cryopreservation of human natural killer cell line NK-92 for clinical manufacturing.
    Lee S; Joo Y; Lee EJ; Byeon Y; Kim JH; Pyo KH; Kim YS; Lim SM; Kilbride P; Iyer RK; Li M; French MC; Lee JY; Kang J; Byun H; Cho BC
    PLoS One; 2024; 19(2):e0294857. PubMed ID: 38394177
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated cancer Immunotherapy.
    Cho Y; Kang M; Ji SH; Jeong HJ; Jung JE; Oh DH; Park S; Park YY; Choi J; Kim S; Kim NJ; Lee DH; Park CS; Han SJ; Lee S; Choi J
    J Med Chem; 2023 Nov; 66(22):15141-15170. PubMed ID: 37963811
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Therapy of autoimmune inflammation in sporadic amyotrophic lateral sclerosis: Dimethyl fumarate and H-151 downregulate inflammatory cytokines in the cGAS-STING pathway.
    Zamiri K; Kesari S; Paul K; Hwang SH; Hammock B; Kaczor-Urbanowicz KE; Urbanowicz A; Gao L; Whitelegge J; Fiala M
    FASEB J; 2023 Aug; 37(8):e23068. PubMed ID: 37436778
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring.
    Nakhle J; Khattar K; Özkan T; Boughlita A; Abba Moussa D; Darlix A; Lorcy F; Rigau V; Bauchet L; Gerbal-Chaloin S; Daujat-Chavanieu M; Bellvert F; Turchi L; Virolle T; Hugnot JP; Buisine N; Galloni M; Dardalhon V; Rodriguez AM; Vignais ML
    Cancer Res Commun; 2023 Jun; 3(6):1041-1056. PubMed ID: 37377608
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT.
    Al Khatib I; Deng J; Lei Y; Torres-Odio S; Rojas GR; Newman LE; Chung BK; Symes A; Zhang H; Huang SN; Pommier Y; Khan A; Shadel GS; West AP; Gibson WT; Shutt TE
    Hum Mol Genet; 2023 Jul; 32(15):2422-2440. PubMed ID: 37129502
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. PKR induces TGF-β and limits oncolytic immune therapy.
    Hong B; Sahu U; Mullarkey MP; Hong E; Pei G; Yan Y; Otani Y; Banasavadi-Siddegowda Y; Fan H; Zhao Z; Yu J; Caligiuri MA; Kaur B
    J Immunother Cancer; 2023 Feb; 11(2):. PubMed ID: 36796878
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The role of STING signaling in central nervous system infection and neuroinflammatory disease.
    Fritsch LE; Kelly C; Pickrell AM
    WIREs Mech Dis; 2023; 15(3):e1597. PubMed ID: 36632700
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.
    Haase S; Banerjee K; Mujeeb AA; Hartlage CS; Núñez FM; Núñez FJ; Alghamri MS; Kadiyala P; Carney S; Barissi MN; Taher AW; Brumley EK; Thompson S; Dreyer JT; Alindogan CT; Garcia-Fabiani MB; Comba A; Venneti S; Ravikumar V; Koschmann C; Carcaboso ÁM; Vinci M; Rao A; Yu JS; Lowenstein PR; Castro MG
    J Clin Invest; 2022 Nov; 132(22):. PubMed ID: 36125896
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS.
    Wang F; Zhao M; Chang B; Zhou Y; Wu X; Ma M; Liu S; Cao Y; Zheng M; Dang Y; Xu J; Chen L; Liu T; Tang F; Ren Y; Xu Z; Mao Z; Huang K; Luo M; Li J; Liu H; Ge B
    Mol Cell; 2022 Jun; 82(11):2032-2049.e7. PubMed ID: 35460603
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Tumor Treating Fields dually activate STING and AIM2 inflammasomes to induce adjuvant immunity in glioblastoma.
    Chen D; Le SB; Hutchinson TE; Calinescu AA; Sebastian M; Jin D; Liu T; Ghiaseddin A; Rahman M; Tran DD
    J Clin Invest; 2022 Apr; 132(8):. PubMed ID: 35199647
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Rationally designed drug delivery systems for the local treatment of resected glioblastoma.
    Bastiancich C; Malfanti A; Préat V; Rahman R
    Adv Drug Deliv Rev; 2021 Oct; 177():113951. PubMed ID: 34461201
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A.
    Lepelley A; Della Mina E; Van Nieuwenhove E; Waumans L; Fraitag S; Rice GI; Dhir A; Frémond ML; Rodero MP; Seabra L; Carter E; Bodemer C; Buhas D; Callewaert B; de Lonlay P; De Somer L; Dyment DA; Faes F; Grove L; Holden S; Hully M; Kurian MA; McMillan HJ; Suetens K; Tyynismaa H; Chhun S; Wai T; Wouters C; Bader-Meunier B; Crow YJ
    J Exp Med; 2021 Oct; 218(10):. PubMed ID: 34387651
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Recognition of the organ-specific mutations in metastatic breast cancer by circulating tumor cells isolated in vivo.
    Li S; Yang S; Shi J; Ding Y; Gao W; Cheng M; Sun Y; Xie Y; Sang M; Yang H; Geng C
    Neoplasma; 2021 Jan; 68(1):31-39. PubMed ID: 32940042
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Safety and Stability of Antibody-Dye Conjugate in Optical Molecular Imaging.
    Pei J; Juniper G; van den Berg NS; Nisho N; Broadt T; Welch AR; Yi GS; Raymundo RC; Chirita SU; Lu G; Krishnan G; Lee YJ; Kapoor S; Zhou Q; Colevas AD; Lui NS; Poultsides GA; Li G; Zinn KR; Rosenthal EL
    Mol Imaging Biol; 2021 Feb; 23(1):109-116. PubMed ID: 32880818
    [TBL] [Abstract] [Full Text] [Related]  

  • 15.
    Vallejo-Armenta P; Santos-Cuevas C; Soto-Andonaegui J; Villanueva-Pérez RM; González-Díaz JI; García-Pérez FO; Arrellano-Zarate A; Luna-Gutiérrez M; Azorín-Vega E; Ocampo-García B; Ferro-Flores G
    Contrast Media Mol Imaging; 2020; 2020():2525037. PubMed ID: 32410920
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.
    Zhou C; Chen X; Planells-Cases R; Chu J; Wang L; Cao L; Li Z; López-Cayuqueo KI; Xie Y; Ye S; Wang X; Ullrich F; Ma S; Fang Y; Zhang X; Qian Z; Liang X; Cai SQ; Jiang Z; Zhou D; Leng Q; Xiao TS; Lan K; Yang J; Li H; Peng C; Qiu Z; Jentsch TJ; Xiao H
    Immunity; 2020 May; 52(5):767-781.e6. PubMed ID: 32277911
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.
    von Roemeling CA; Wang Y; Qie Y; Yuan H; Zhao H; Liu X; Yang Z; Yang M; Deng W; Bruno KA; Chan CK; Lee AS; Rosenfeld SS; Yun K; Johnson AJ; Mitchell DA; Jiang W; Kim BYS
    Nat Commun; 2020 Mar; 11(1):1508. PubMed ID: 32198351
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The Horizon of Gene Therapy in Modern Medicine: Advances and Challenges.
    Arjmand B; Larijani B; Sheikh Hosseini M; Payab M; Gilany K; Goodarzi P; Parhizkar Roudsari P; Amanollahi Baharvand M; Hoseini Mohammadi NS
    Adv Exp Med Biol; 2020; 1247():33-64. PubMed ID: 31845133
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma.
    Wolfe K; Kofuji S; Yoshino H; Sasaki M; Okumura K; Sasaki AT
    Biochem Biophys Res Commun; 2019 Aug; 516(1):50-56. PubMed ID: 31196624
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Initial experience in synthesis of (2S,4R)-4-[
    Zhang Y; Zhang L; Yang J; Wu Z; Ploessl K; Zha Z; Liu F; Xu X; Zhu H; Yang Z; Zhu L; Kung HF
    J Labelled Comp Radiopharm; 2019 May; 62(5):209-214. PubMed ID: 30861162
    [TBL] [Abstract] [Full Text] [Related]  


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