BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND NTRK1, ENSG00000198400, 4914, P04629, TRK1, MTC, DKFZp781I14186, p140-TrkA, TRKA, TRK AND Prognosis
34 results:

  • 1. BDNF/trkB axis provokes EMT progression to induce cell aggressiveness via crosstalk with cancer-associated fibroblasts in human parotid gland cancer.
    Moriwaki K; Wada M; Kuwabara H; Ayani Y; Terada T; Higashino M; Kawata R; Asahi M
    Sci Rep; 2022 Oct; 12(1):17553. PubMed ID: 36266462
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. BDNF and its signaling in cancer.
    Malekan M; Nezamabadi SS; Samami E; Mohebalizadeh M; Saghazadeh A; Rezaei N
    J Cancer Res Clin Oncol; 2023 Jun; 149(6):2621-2636. PubMed ID: 36173463
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Detection of Ntrk fusions in glioblastoma: fluorescent in situ hybridisation is more useful than pan-trk immunohistochemistry as a screening tool prior to RNA sequencing.
    Bourhis A; Caumont C; Quintin-Roué I; Magro E; Dissaux G; Remoué A; Le Noac'h P; Douet-Guilbert N; Seizeur R; Tyulyandina A; Schick U; Merlio JP; Marcorelles P; Cappellen D; Uguen A
    Pathology; 2022 Feb; 54(1):55-62. PubMed ID: 34518039
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Clinicopathological findings of pediatric Ntrk fusion mesenchymal tumors.
    Kang J; Park JW; Won JK; Bae JM; Koh J; Yim J; Yun H; Kim SK; Choi JY; Kang HJ; Kim WS; Shin JH; Park SH
    Diagn Pathol; 2020 Sep; 15(1):114. PubMed ID: 32957984
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Advances in Regulating Tumorigenicity and Metastasis of cancer Through trkB Signaling.
    Zou W; Hu X; Jiang L
    Curr Cancer Drug Targets; 2020; 20(10):779-788. PubMed ID: 32748747
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A novel PTPRZ1-ETV1 fusion in gliomas.
    Matjašič A; Zupan A; Boštjančič E; Pižem J; Popović M; Kolenc D
    Brain Pathol; 2020 Mar; 30(2):226-234. PubMed ID: 31381204
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Tropomyosin-Related Kinase Receptor and Neurotrophin Expression in Cutaneous Melanoma Is Associated with a Poor prognosis and Decreased Survival.
    Antunes LCM; Cartell A; de Farias CB; Bakos RM; Roesler R; Schwartsmann G
    Oncology; 2019; 97(1):26-37. PubMed ID: 31071716
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The presence of Y674/Y675 phosphorylated ntrk1 via TP53 repression of PTPN6 expression as a potential prognostic marker in neuroblastoma.
    Youssef G; Gillett C; Rampling D; Chagtai T; Virasami A; Barton J; Edwards D; Sebire N; Anderson J; Montano X
    Hum Pathol; 2019 Apr; 86():182-192. PubMed ID: 30594749
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Combined c-Met/trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.
    Olmez I; Zhang Y; Manigat L; Benamar M; Brenneman B; Nakano I; Godlewski J; Bronisz A; Lee J; Abbas T; Abounader R; Purow B
    Cancer Res; 2018 Aug; 78(15):4360-4369. PubMed ID: 29844123
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Expression of brain-derived neurotrophic factor and its receptor trkB is associated with poor prognosis and a malignant phenotype in small cell lung cancer.
    Kimura S; Harada T; Ijichi K; Tanaka K; Liu R; Shibahara D; Kawano Y; Otsubo K; Yoneshima Y; Iwama E; Nakanishi Y; Okamoto I
    Lung Cancer; 2018 Jun; 120():98-107. PubMed ID: 29748024
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Somatostatin receptor subtype 1 might be a predictor of better response to therapy in medullary thyroid carcinoma.
    Kendler DB; Araújo ML; Alencar R; de Souza Accioly MT; Bulzico DA; de Noronha Pessoa CC; Accioly FA; de Farias TP; Lopes FPPL; Corbo R; Vaisman M; Vaisman F
    Endocrine; 2017 Dec; 58(3):474-480. PubMed ID: 28948577
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Uncovering the role of brain-derived neurotrophic factor/tyrosine kinase receptor B signaling in head and neck malignancies.
    de Moraes JK; Wagner VP; Fonseca FP; Vargas PA; de Farias CB; Roesler R; Martins MD
    J Oral Pathol Med; 2018 Mar; 47(3):221-227. PubMed ID: 28650560
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. brain-derived neurotrophic factor/tropomyosin-related kinase B signaling pathway contributes to the aggressive behavior of lung squamous cell carcinoma.
    Ozono K; Ohishi Y; Onishi H; Nakamura K; Motoshita J; Kato M; Nakanishi R; Nakamura M; Oda Y
    Lab Invest; 2017 Nov; 97(11):1332-1342. PubMed ID: 28604655
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Perineural growth in head and neck squamous cell carcinoma: a review.
    Roh J; Muelleman T; Tawfik O; Thomas SM
    Oral Oncol; 2015 Jan; 51(1):16-23. PubMed ID: 25456006
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer.
    Tanaka K; Okugawa Y; Toiyama Y; Inoue Y; Saigusa S; Kawamura M; Araki T; Uchida K; Mohri Y; Kusunoki M
    PLoS One; 2014; 9(5):e96410. PubMed ID: 24801982
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. brain-derived neurotrophic factor/tropomyosin-related kinase B pathway in gastric cancer.
    Okugawa Y; Tanaka K; Inoue Y; Kawamura M; Kawamoto A; Hiro J; Saigusa S; Toiyama Y; Ohi M; Uchida K; Mohri Y; Kusunoki M
    Br J Cancer; 2013 Jan; 108(1):121-30. PubMed ID: 23175149
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. trks are novel oncogenes involved in the induction of neovascularization, tumor progression, and nodal metastasis in oral squamous cell carcinoma.
    Sasahira T; Ueda N; Yamamoto K; Bhawal UK; Kurihara M; Kirita T; Kuniyasu H
    Clin Exp Metastasis; 2013 Feb; 30(2):165-76. PubMed ID: 22886570
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The selective trk inhibitor AZ623 inhibits brain-derived neurotrophic factor-mediated neuroblastoma cell proliferation and signaling and is synergistic with topotecan.
    Zage PE; Graham TC; Zeng L; Fang W; Pien C; Thress K; Omer C; Brown JL; Zweidler-McKay PA
    Cancer; 2011 Mar; 117(6):1321-91. PubMed ID: 20960503
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Lestaurtinib enhances the antitumor efficacy of chemotherapy in murine xenograft models of neuroblastoma.
    Iyer R; Evans AE; Qi X; Ho R; Minturn JE; Zhao H; Balamuth N; Maris JM; Brodeur GM
    Clin Cancer Res; 2010 Mar; 16(5):1478-85. PubMed ID: 20179224
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. On trk--the trkB signal transduction pathway is an increasingly important target in cancer biology.
    Thiele CJ; Li Z; McKee AE
    Clin Cancer Res; 2009 Oct; 15(19):5962-7. PubMed ID: 19755385
    [TBL] [Abstract] [Full Text] [Related]  


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