Terms: = Brain cancer AND PDGFRA, MGC74795, 5156, ENSG00000134853, PDGFR2, CD140A, Rhe-PDGFRA, CD140a, P16234
236 results:
1. Pediatric-type high-grade gliomas with pdgfra amplification in adult patients with Li-Fraumeni syndrome: clinical and molecular characterization of three cases.
Kibe Y; Ohka F; Aoki K; Yamaguchi J; Motomura K; Ito E; Takeuchi K; Nagata Y; Ito S; Mizutani N; Shiba Y; Maeda S; Nishikawa T; Shimizu H; Saito R
Acta Neuropathol Commun; 2024 Apr; 12(1):57. PubMed ID: 38605367
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2. pdgfra K385 mutants in myxoid glioneuronal tumors promote receptor dimerization and oncogenic signaling.
de Villenfagne L; Sablon A; Demoulin JB
Sci Rep; 2024 Mar; 14(1):7204. PubMed ID: 38532028
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3. Clinical and molecular study of radiation-induced gliomas.
Trkova K; Sumerauer D; Bubenikova A; Krskova L; Vicha A; Koblizek M; Zamecnik J; Jurasek B; Kyncl M; Malinova B; Ondrova B; Jones DTW; Sill M; Strnadova M; Stolova L; Misove A; Benes V; Zapotocky M
Sci Rep; 2024 Feb; 14(1):3118. PubMed ID: 38326438
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4. Avapritinib-based SAR studies unveil a binding pocket in KIT and pdgfra.
Teuber A; Schulz T; Fletcher BS; Gontla R; Mühlenberg T; Zischinsky ML; Niggenaber J; Weisner J; Kleinbölting SB; Lategahn J; Sievers S; Müller MP; Bauer S; Rauh D
Nat Commun; 2024 Jan; 15(1):63. PubMed ID: 38167404
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5. Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression.
Appin CL; Hong C; Suwala AK; Hilz S; Mathur R; Solomon DA; Smirnov IV; Stevers NO; Shai A; Wang A; Berger MS; Chang SM; Phillips JJ; Costello JF
Neuro Oncol; 2024 Apr; 26(4):640-652. PubMed ID: 38141254
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6. "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
Hadad S; Gupta R; Oberheim Bush NA; Taylor JW; Villanueva-Meyer JE; Young JS; Wu J; Ravindranathan A; Zhang Y; Warrier G; McCoy L; Shai A; Pekmezci M; Perry A; Bollen AW; Phillips JJ; Braunstein SE; Raleigh DR; Theodosopoulos P; Aghi MK; Chang EF; Hervey-Jumper SL; Costello JF; de Groot J; Butowski NA; Clarke JL; Chang SM; Berger MS; Molinaro AM; Solomon DA
Acta Neuropathol; 2023 Dec; 147(1):3. PubMed ID: 38079020
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7. Genetic alterations that deregulate RB and pdgfra signaling pathways drive tumor progression in IDH2-mutant astrocytoma.
Tateishi K; Miyake Y; Nakamura T; Iwashita H; Hayashi T; Oshima A; Honma H; Hayashi H; Sugino K; Kato M; Satomi K; Fujii S; Komori T; Yamamoto T; Cahill DP; Wakimoto H
Acta Neuropathol Commun; 2023 Nov; 11(1):186. PubMed ID: 38012788
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8. Fgf2 and Ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia.
Zhang L; Xu L
Medicine (Baltimore); 2023 Nov; 102(45):e36108. PubMed ID: 37960778
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9. Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.
Rautajoki KJ; Jaatinen S; Hartewig A; Tiihonen AM; Annala M; Salonen I; Valkonen M; Simola V; Vuorinen EM; Kivinen A; Rauhala MJ; Nurminen R; Maass KK; Lahtela SL; Jukkola A; Yli-Harja O; Helén P; Pajtler KW; Ruusuvuori P; Haapasalo J; Zhang W; Haapasalo H; Nykter M
Acta Neuropathol Commun; 2023 Nov; 11(1):176. PubMed ID: 37932833
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10. Сell clusters isolation in glioblastomas and their functional and molecular characterization using new morphometric approaches.
Nikitin PV; Musina GR; Fayzullin AL; Bakulina AA; Nikolaev VN; Mikhailov VP; Werkenbark L; Kjelin M; Usachev DY; Timashev PS
Comput Biol Med; 2023 Sep; 164():107322. PubMed ID: 37582322
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11. ROS1 Alterations as a Potential Driver of Gliomas in Infant, Pediatric, and Adult Patients.
Meredith DM; Cooley LD; Dubuc A; Morrissette J; Sussman RT; Nasrallah MP; Rathbun P; Yap KL; Wadhwani N; Bao L; Wolff DJ; Ida C; Sukhanova M; Horbinski C; Jennings LJ; Farooqi M; Gener M; Ginn K; Kam KL; Sasaki K; Kanagal-Shamanna R; Alexandrescu S; Brat D; Lu X
Mod Pathol; 2023 Nov; 36(11):100294. PubMed ID: 37532182
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12. A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4.
Williams EA; Brastianos PK; Wakimoto H; Zolal A; Filbin MG; Cahill DP; Santagata S; Juratli TA
Acta Neuropathol; 2023 Sep; 146(3):515-525. PubMed ID: 37524847
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13. Modeling epigenetic lesions that cause gliomas.
Rahme GJ; Javed NM; Puorro KL; Xin S; Hovestadt V; Johnstone SE; Bernstein BE
Cell; 2023 Aug; 186(17):3674-3685.e14. PubMed ID: 37494934
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14. Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high-grade gliomas.
Reuss DE; Downing SM; Camacho CV; Wang YD; Piro RM; Herold-Mende C; Wang ZQ; Hofmann TG; Sahm F; von Deimling A; McKinnon PJ; Frappart PO
Neuropathol Appl Neurobiol; 2023 Aug; 49(4):e12915. PubMed ID: 37296499
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15. A review on the role of SNHG8 in human disorders.
Ghafouri-Fard S; Harsij A; Hussen BM; Taheri M; Ayatollahi SA
Pathol Res Pract; 2023 May; 245():154458. PubMed ID: 37043963
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16. Oncogenic long noncoding RNA LINC02283 enhances PDGF receptor A-mediated signaling and drives glioblastoma tumorigenesis.
Goenka A; Song X; Tiek D; Iglesia RP; Lu M; Zeng C; Horbinski C; Zhang W; Hu B; Cheng SY
Neuro Oncol; 2023 Sep; 25(9):1592-1604. PubMed ID: 36988488
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17. H3 G34-mutant high-grade gliomas: integrated clinical, imaging and pathological characterisation of a single-centre case series.
Lavrador JP; Reisz Z; Sibtain N; Rajwani K; Baig Mirza A; Vergani F; Gullan R; Bhangoo R; Ashkan K; Bleil C; Zebian B; Clark B; Laxton R; King A; Bodi I; Al-Saraj S
Acta Neurochir (Wien); 2023 Jun; 165(6):1615-1633. PubMed ID: 36929449
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18. Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma.
Walentynowicz KA; Engelhardt D; Cristea S; Yadav S; Onubogu U; Salatino R; Maerken M; Vincentelli C; Jhaveri A; Geisberg J; McDonald TO; Michor F; Janiszewska M
Cell Rep; 2023 Mar; 42(3):112235. PubMed ID: 36920905
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19. Valtrate, an iridoid compound in Valeriana, elicits anti-glioblastoma activity through inhibition of the pdgfra/MEK/ERK signaling pathway.
Liu X; Hu Y; Xue Z; Zhang X; Liu X; Liu G; Wen M; Chen A; Huang B; Li X; Yang N; Wang J
J Transl Med; 2023 Feb; 21(1):147. PubMed ID: 36829235
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20. Myxoid glioneuronal tumor: Histopathologic, neuroradiologic, and molecular features in a single center series.
Caporalini C; Scagnet M; Giunti L; Cetica V; Mei D; Conti V; Moscardi S; Macconi L; Giordano F; D'Incerti L; Genitori L; Guerrini R; Buccoliero AM
Neoplasia; 2023 Mar; 37():100885. PubMed ID: 36764090
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