BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND PDGFRA, MGC74795, 5156, ENSG00000134853, PDGFR2, CD140A, Rhe-PDGFRA, CD140a, P16234 AND Prognosis
58 results:

  • 1. Clinical and molecular study of radiation-induced gliomas.
    Trkova K; Sumerauer D; Bubenikova A; Krskova L; Vicha A; Koblizek M; Zamecnik J; Jurasek B; Kyncl M; Malinova B; Ondrova B; Jones DTW; Sill M; Strnadova M; Stolova L; Misove A; Benes V; Zapotocky M
    Sci Rep; 2024 Feb; 14(1):3118. PubMed ID: 38326438
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Avapritinib-based SAR studies unveil a binding pocket in KIT and pdgfra.
    Teuber A; Schulz T; Fletcher BS; Gontla R; Mühlenberg T; Zischinsky ML; Niggenaber J; Weisner J; Kleinbölting SB; Lategahn J; Sievers S; Müller MP; Bauer S; Rauh D
    Nat Commun; 2024 Jan; 15(1):63. PubMed ID: 38167404
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Fgf2 and Ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia.
    Zhang L; Xu L
    Medicine (Baltimore); 2023 Nov; 102(45):e36108. PubMed ID: 37960778
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.
    Rautajoki KJ; Jaatinen S; Hartewig A; Tiihonen AM; Annala M; Salonen I; Valkonen M; Simola V; Vuorinen EM; Kivinen A; Rauhala MJ; Nurminen R; Maass KK; Lahtela SL; Jukkola A; Yli-Harja O; Helén P; Pajtler KW; Ruusuvuori P; Haapasalo J; Zhang W; Haapasalo H; Nykter M
    Acta Neuropathol Commun; 2023 Nov; 11(1):176. PubMed ID: 37932833
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high-grade gliomas.
    Reuss DE; Downing SM; Camacho CV; Wang YD; Piro RM; Herold-Mende C; Wang ZQ; Hofmann TG; Sahm F; von Deimling A; McKinnon PJ; Frappart PO
    Neuropathol Appl Neurobiol; 2023 Aug; 49(4):e12915. PubMed ID: 37296499
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Oncogenic long noncoding RNA LINC02283 enhances PDGF receptor A-mediated signaling and drives glioblastoma tumorigenesis.
    Goenka A; Song X; Tiek D; Iglesia RP; Lu M; Zeng C; Horbinski C; Zhang W; Hu B; Cheng SY
    Neuro Oncol; 2023 Sep; 25(9):1592-1604. PubMed ID: 36988488
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Valtrate, an iridoid compound in Valeriana, elicits anti-glioblastoma activity through inhibition of the pdgfra/MEK/ERK signaling pathway.
    Liu X; Hu Y; Xue Z; Zhang X; Liu X; Liu G; Wen M; Chen A; Huang B; Li X; Yang N; Wang J
    J Transl Med; 2023 Feb; 21(1):147. PubMed ID: 36829235
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Oncogene expression from extrachromosomal DNA is driven by copy number amplification and does not require spatial clustering in glioblastoma stem cells.
    Purshouse K; Friman ET; Boyle S; Dewari PS; Grant V; Hamdan A; Morrison GM; Brennan PM; Beentjes SV; Pollard SM; Bickmore WA
    Elife; 2022 Dec; 11():. PubMed ID: 36476408
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Co-amplified with pdgfra, IGFBP7 is a prognostic biomarker correlated with the immune infiltrations of glioma.
    Wang H; Wang X; Xu L; Zhang J
    Cancer Med; 2023 Feb; 12(4):4951-4967. PubMed ID: 36043552
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Molecular Genetics and Targeted Therapies for Paediatric High-grade Glioma.
    Rallis KS; George AM; Wozniak AM; Bigogno CM; Chow B; Hanrahan JG; Sideris M
    Cancer Genomics Proteomics; 2022; 19(4):390-414. PubMed ID: 35732328
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Tumor Heterogeneity and Molecular Characteristics of Glioblastoma Revealed by Single-Cell RNA-Seq Data Analysis.
    Yesudhas D; Dharshini SAP; Taguchi YH; Gromiha MM
    Genes (Basel); 2022 Feb; 13(3):. PubMed ID: 35327982
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The prognostic significance of further genotyping H3G34 diffuse hemispheric gliomas.
    Vuong HG; Le HT; Dunn IF
    Cancer; 2022 May; 128(10):1907-1912. PubMed ID: 35195909
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. High frequency of pdgfra and MUC family gene mutations in diffuse hemispheric glioma, H3 G34-mutant: a glimmer of hope?
    Hu W; Duan H; Zhong S; Zeng J; Mou Y
    J Transl Med; 2022 Feb; 20(1):64. PubMed ID: 35109850
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating pdgfra.
    Chen S; Zhang Z; Zhang B; Huang Q; Liu Y; Qiu Y; Long X; Wu M; Zhang Z
    Int J Biol Sci; 2022; 18(2):841-857. PubMed ID: 35002529
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Mismatch repair proteins PMS2 and MLH1 can further refine molecular stratification of IDH-mutant lower grade astrocytomas.
    Yang RR; Li KK; Zhang ZY; Chan AK; Wang WW; Chan DT; Li WC; Liu XZ; Li FC; Chen H; Ng HK; Mao Y; Shi ZF
    Clin Neurol Neurosurg; 2021 Sep; 208():106882. PubMed ID: 34428613
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. [Clinicopathological and molecular genetic characteristics of adult IDH wild-type diffuse gliomas].
    Wang LM; Wang W; Liu L; Gao M; Yao YY; Zhang M; Xiong YL; Shao Y; Lu DH; Teng LH
    Zhonghua Bing Li Xue Za Zhi; 2021 Jul; 50(7):734-739. PubMed ID: 34405606
    [No Abstract]    [Full Text] [Related]  

  • 17. Histone H3.3 G34-mutant Diffuse Gliomas in Adults.
    Wang L; Shao L; Li H; Yao K; Duan Z; Zhi C; Song S; Cheng Y; Wang F; Wang W; Piao Y; Gui Q; Lu D; Qi X; Teng L
    Am J Surg Pathol; 2022 Feb; 46(2):249-257. PubMed ID: 34352809
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma.
    Fujimoto K; Arita H; Satomi K; Yamasaki K; Matsushita Y; Nakamura T; Miyakita Y; Umehara T; Kobayashi K; Tamura K; Tanaka S; Higuchi F; Okita Y; Kanemura Y; Fukai J; Sakamoto D; Uda T; Machida R; Kuchiba A; Maehara T; Nagane M; Nishikawa R; Suzuki H; Shibuya M; Komori T; Narita Y; Ichimura K
    Acta Neuropathol; 2021 Aug; 142(2):323-338. PubMed ID: 34148105
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Prognostic significance of genome-wide DNA methylation profiles within the randomized, phase 3, EORTC CATNON trial on non-1p/19q deleted anaplastic glioma.
    Tesileanu CMS; van den Bent MJ; Sanson M; Wick W; Brandes AA; Clement PM; Erridge SC; Vogelbaum MA; Nowak AK; Baurain JF; Mason WP; Wheeler H; Chinot OL; Gill S; Griffin M; Rogers L; Taal W; Rudà R; Weller M; McBain C; van Linde ME; Sabedot TS; Hoogstrate Y; von Deimling A; de Heer I; van IJcken WFJ; Brouwer RWW; Aldape K; Jenkins RB; Dubbink HJ; Kros JM; Wesseling P; Cheung KJ; Golfinopoulos V; Baumert BG; Gorlia T; Noushmehr H; French PJ
    Neuro Oncol; 2021 Sep; 23(9):1547-1559. PubMed ID: 33914057
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Molecular landscape of IDH-mutant primary astrocytoma Grade IV/glioblastomas.
    Wong QH; Li KK; Wang WW; Malta TM; Noushmehr H; Grabovska Y; Jones C; Chan AK; Kwan JS; Huang QJ; Wong GC; Li WC; Liu XZ; Chen H; Chan DT; Mao Y; Zhang ZY; Shi ZF; Ng HK
    Mod Pathol; 2021 Jul; 34(7):1245-1260. PubMed ID: 33692446
    [TBL] [Abstract] [Full Text] [Related]  


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