Terms: = Brain cancer AND PPM1D, Wip1, 8493, ENSG00000170836, O15297, WIP1, PP2C-DELTA
30 results:
1. A Case Study on ppm1d and 9 Other Shared Germline Alterations in a Family.
Biswas S; Manekar S; Bakshi SR
Asian Pac J Cancer Prev; 2023 Jun; 24(6):2129-2134. PubMed ID: 37378944
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2. [Diffuse midline glioma with H3K27 alteration in adults: a clinicopathological analysis].
Yang QY; Li MN; Chen TY; Liu C; Li X; Shi ZM; Pan MH
Zhonghua Bing Li Xue Za Zhi; 2023 Apr; 52(4):376-383. PubMed ID: 36973199
[No Abstract] [Full Text] [Related]
3. Genomic profiling and prognostic factors of H3 K27M-mutant spinal cord diffuse glioma.
Chai RC; Yan H; An SY; Pang B; Chen HY; Mu QH; Zhang KN; Zhang YW; Liu YQ; Liu X; Zhao Z; Jiang T; Wang YZ; Jia WQ
Brain Pathol; 2023 Jul; 33(4):e13153. PubMed ID: 36751054
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4. Structural variants shape driver combinations and outcomes in pediatric high-grade glioma.
Dubois FPB; Shapira O; Greenwald NF; Zack T; Wala J; Tsai JW; Crane A; Baguette A; Hadjadj D; Harutyunyan AS; Kumar KH; Blattner-Johnson M; Vogelzang J; Sousa C; Kang KS; Sinai C; Wang DK; Khadka P; Lewis K; Nguyen L; Malkin H; Ho P; O'Rourke R; Zhang S; Gold R; Deng D; Serrano J; Snuderl M; Jones C; Wright KD; Chi SN; Grill J; Kleinman CL; Goumnerova LC; Jabado N; Jones DTW; Kieran MW; Ligon KL; Beroukhim R; Bandopadhayay P
Nat Cancer; 2022 Aug; 3(8):994-1011. PubMed ID: 35788723
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5. Functionalized Macrophage Exosomes with Panobinostat and ppm1d-siRNA for Diffuse Intrinsic Pontine Gliomas Therapy.
Shan S; Chen J; Sun Y; Wang Y; Xia B; Tan H; Pan C; Gu G; Zhong J; Qing G; Zhang Y; Wang J; Wang Y; Wang Y; Zuo P; Xu C; Li F; Guo W; Xu L; Chen M; Fan Y; Zhang L; Liang XJ
Adv Sci (Weinh); 2022 Jul; 9(21):e2200353. PubMed ID: 35585670
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6. ppm1d mutations are oncogenic drivers of de novo diffuse midline glioma formation.
Khadka P; Reitman ZJ; Lu S; Buchan G; Gionet G; Dubois F; Carvalho DM; Shih J; Zhang S; Greenwald NF; Zack T; Shapira O; Pelton K; Hartley R; Bear H; Georgis Y; Jarmale S; Melanson R; Bonanno K; Schoolcraft K; Miller PG; Condurat AL; Gonzalez EM; Qian K; Morin E; Langhnoja J; Lupien LE; Rendo V; Digiacomo J; Wang D; Zhou K; Kumbhani R; Guerra Garcia ME; Sinai CE; Becker S; Schneider R; Vogelzang J; Krug K; Goodale A; Abid T; Kalani Z; Piccioni F; Beroukhim R; Persky NS; Root DE; Carcaboso AM; Ebert BL; Fuller C; Babur O; Kieran MW; Jones C; Keshishian H; Ligon KL; Carr SA; Phoenix TN; Bandopadhayay P
Nat Commun; 2022 Feb; 13(1):604. PubMed ID: 35105861
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7. TP53 wild-type/ppm1d mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.
Xu C; Liu H; Pirozzi CJ; Chen LH; Greer PK; Diplas BH; Zhang L; Waitkus MS; He Y; Yan H
Acta Neuropathol Commun; 2021 Nov; 9(1):178. PubMed ID: 34732238
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8. Topographic correlates of driver mutations and endogenous gene expression in pediatric diffuse midline gliomas and hemispheric high-grade gliomas.
Kazarian E; Marks A; Cui J; Darbinyan A; Tong E; Mueller S; Cha S; Aboian MS
Sci Rep; 2021 Jul; 11(1):14377. PubMed ID: 34257334
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9. Molecular Determinants of Medulloblastoma Metastasis and Leptomeningeal Dissemination.
Li M; Deng Y; Zhang W
Mol Cancer Res; 2021 May; 19(5):743-752. PubMed ID: 33608450
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10. brain metastasis detection using machine learning: a systematic review and meta-analysis.
Cho SJ; Sunwoo L; Baik SH; Bae YJ; Choi BS; Kim JH
Neuro Oncol; 2021 Feb; 23(2):214-225. PubMed ID: 33075135
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11. Targeting Mutant ppm1d Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.
Wang Z; Xu C; Diplas BH; Moure CJ; Chen CJ; Chen LH; Du C; Zhu H; Greer PK; Zhang L; He Y; Waitkus MS; Yan H
Mol Cancer Res; 2020 Jul; 18(7):968-980. PubMed ID: 32229503
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12. ppm1d mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
Fons NR; Sundaram RK; Breuer GA; Peng S; McLean RL; Kalathil AN; Schmidt MS; Carvalho DM; Mackay A; Jones C; Carcaboso ÁM; Nazarian J; Berens ME; Brenner C; Bindra RS
Nat Commun; 2019 Aug; 10(1):3790. PubMed ID: 31439867
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13. Inhibition of mutant ppm1d enhances DNA damage response and growth suppressive effects of ionizing radiation in diffuse intrinsic pontine glioma.
Akamandisa MP; Nie K; Nahta R; Hambardzumyan D; Castellino RC
Neuro Oncol; 2019 Jun; 21(6):786-799. PubMed ID: 30852603
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14. Distinct molecular profile of diffuse cerebellar gliomas.
Nomura M; Mukasa A; Nagae G; Yamamoto S; Tatsuno K; Ueda H; Fukuda S; Umeda T; Suzuki T; Otani R; Kobayashi K; Maruyama T; Tanaka S; Takayanagi S; Nejo T; Takahashi S; Ichimura K; Nakamura T; Muragaki Y; Narita Y; Nagane M; Ueki K; Nishikawa R; Shibahara J; Aburatani H; Saito N
Acta Neuropathol; 2017 Dec; 134(6):941-956. PubMed ID: 28852847
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15. De Novo Truncating Mutations in the Last and Penultimate Exons of ppm1d Cause an Intellectual Disability Syndrome.
Jansen S; Geuer S; Pfundt R; Brough R; Ghongane P; Herkert JC; Marco EJ; Willemsen MH; Kleefstra T; Hannibal M; Shieh JT; Lynch SA; Flinter F; FitzPatrick DR; Gardham A; Bernhard B; Ragge N; Newbury-Ecob R; Bernier R; Kvarnung M; Magnusson EA; Wessels MW; van Slegtenhorst MA; Monaghan KG; de Vries P; Veltman JA; ; Lord CJ; Vissers LE; de Vries BB
Am J Hum Genet; 2017 Apr; 100(4):650-658. PubMed ID: 28343630
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16. wip1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.
Wen J; Lee J; Malhotra A; Nahta R; Arnold AR; Buss MC; Brown BD; Maier C; Kenney AM; Remke M; Ramaswamy V; Taylor MD; Castellino RC
Oncogene; 2016 Oct; 35(42):5552-5564. PubMed ID: 27086929
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17. Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.
Nikbakht H; Panditharatna E; Mikael LG; Li R; Gayden T; Osmond M; Ho CY; Kambhampati M; Hwang EI; Faury D; Siu A; Papillon-Cavanagh S; Bechet D; Ligon KL; Ellezam B; Ingram WJ; Stinson C; Moore AS; Warren KE; Karamchandani J; Packer RJ; Jabado N; Majewski J; Nazarian J
Nat Commun; 2016 Apr; 7():11185. PubMed ID: 27048880
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18. Expression and gene doses changes of the p53-regulator ppm1d in meningiomas: a role in meningioma progression?
Fukami S; Riemenschneider MJ; Kohno M; Steiger HJ
Brain Tumor Pathol; 2016 Jul; 33(3):191-9. PubMed ID: 26942600
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19. Biallelic FANCD1/BRCA2 mutations predisposing to glioblastoma multiforme with multiple oncogenic amplifications.
Dodgshun AJ; Sexton-Oates A; Saffery R; Sullivan MJ
Cancer Genet; 2016; 209(1-2):53-6. PubMed ID: 26740091
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20. Exome sequencing identifies somatic gain-of-function ppm1d mutations in brainstem gliomas.
Zhang L; Chen LH; Wan H; Yang R; Wang Z; Feng J; Yang S; Jones S; Wang S; Zhou W; Zhu H; Killela PJ; Zhang J; Wu Z; Li G; Hao S; Wang Y; Webb JB; Friedman HS; Friedman AH; McLendon RE; He Y; Reitman ZJ; Bigner DD; Yan H
Nat Genet; 2014 Jul; 46(7):726-30. PubMed ID: 24880341
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