Terms: = Brain cancer AND PPM1D, Wip1, 8493, ENSG00000170836, O15297, WIP1, PP2C-DELTA AND Treatment
8 results:
1. TP53 wild-type/ppm1d mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.
Xu C; Liu H; Pirozzi CJ; Chen LH; Greer PK; Diplas BH; Zhang L; Waitkus MS; He Y; Yan H
Acta Neuropathol Commun; 2021 Nov; 9(1):178. PubMed ID: 34732238
[TBL] [Abstract] [Full Text] [Related]
2. Targeting Mutant ppm1d Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.
Wang Z; Xu C; Diplas BH; Moure CJ; Chen CJ; Chen LH; Du C; Zhu H; Greer PK; Zhang L; He Y; Waitkus MS; Yan H
Mol Cancer Res; 2020 Jul; 18(7):968-980. PubMed ID: 32229503
[TBL] [Abstract] [Full Text] [Related]
3. ppm1d mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
Fons NR; Sundaram RK; Breuer GA; Peng S; McLean RL; Kalathil AN; Schmidt MS; Carvalho DM; Mackay A; Jones C; Carcaboso ÁM; Nazarian J; Berens ME; Brenner C; Bindra RS
Nat Commun; 2019 Aug; 10(1):3790. PubMed ID: 31439867
[TBL] [Abstract] [Full Text] [Related]
4. Inhibition of mutant ppm1d enhances DNA damage response and growth suppressive effects of ionizing radiation in diffuse intrinsic pontine glioma.
Akamandisa MP; Nie K; Nahta R; Hambardzumyan D; Castellino RC
Neuro Oncol; 2019 Jun; 21(6):786-799. PubMed ID: 30852603
[TBL] [Abstract] [Full Text] [Related]
5. wip1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.
Wen J; Lee J; Malhotra A; Nahta R; Arnold AR; Buss MC; Brown BD; Maier C; Kenney AM; Remke M; Ramaswamy V; Taylor MD; Castellino RC
Oncogene; 2016 Oct; 35(42):5552-5564. PubMed ID: 27086929
[TBL] [Abstract] [Full Text] [Related]
6. HDM2 promotes wip1-mediated medulloblastoma growth.
Buss MC; Read TA; Schniederjan MJ; Gandhi K; Castellino RC
Neuro Oncol; 2012 Apr; 14(4):440-58. PubMed ID: 22379189
[TBL] [Abstract] [Full Text] [Related]
7. Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma.
Mendrzyk F; Radlwimmer B; Joos S; Kokocinski F; Benner A; Stange DE; Neben K; Fiegler H; Carter NP; Reifenberger G; Korshunov A; Lichter P
J Clin Oncol; 2005 Dec; 23(34):8853-62. PubMed ID: 16314645
[TBL] [Abstract] [Full Text] [Related]
8. Relationship between pattern of enhancement and local control of brain metastases after radiosurgery.
Goodman KA; Sneed PK; McDermott MW; Shiau CY; Lamborn KR; Chang S; Park E; Wara WM; Larson DA
Int J Radiat Oncol Biol Phys; 2001 May; 50(1):139-46. PubMed ID: 11316557
[TBL] [Abstract] [Full Text] [Related]
