Terms: = Brain cancer AND PTCH1, RP11-435O5_3, Q13635, PTCH, 5727, HPE7, FLJ26746, NBCCS, BCNS, PTC1, ENSG00000185920, FLJ42602 AND Prognosis
22 results:
1. Molecular Stratification of Medulloblastoma: Clinical Outcomes and Therapeutic Interventions.
Sursal T; Ronecker JS; Dicpinigaitis AJ; Mohan AL; Tobias ME; Gandhi CD; Jhanwar-Uniyal M
Anticancer Res; 2022 May; 42(5):2225-2239. PubMed ID: 35489737
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2. Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.
Korshunov A; Okonechnikov K; Stichel D; Ryzhova M; Schrimpf D; Sahm F; Sievers P; Absalyamova O; Zheludkova O; Golanov A; Jones DTW; Pfister SM; von Deimling A; Kool M
Neuro Oncol; 2021 Sep; 23(9):1576-1585. PubMed ID: 33589929
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3. Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.
Korshunov A; Okonechnikov K; Sahm F; Ryzhova M; Stichel D; Schrimpf D; Ghasemi DR; Pajtler KW; Antonelli M; Donofrio V; Mastronuzzi A; Rossi S; Camassei FD; Buccoliero AM; Haberler C; Slavc I; Dahiya S; Casalini B; Sievers P; Meyer J; Kumirova E; Zheludkova O; Golanov A; Jones DTW; Pfister SM; Kool M; von Deimling A
Acta Neuropathol; 2020 Mar; 139(3):583-596. PubMed ID: 31781912
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4. Targeting cyclin-dependent kinase 9 sensitizes medulloblastoma cells to chemotherapy.
Song H; Bhakat R; Kling MJ; Coulter DW; Chaturvedi NK; Ray S; Joshi SS
Biochem Biophys Res Commun; 2019 Dec; 520(2):250-256. PubMed ID: 31594641
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5. Principles of tumorigenesis and emerging molecular drivers of SHH-activated medulloblastomas.
Menyhárt O; Győrffy B
Ann Clin Transl Neurol; 2019 May; 6(5):990-1005. PubMed ID: 31139698
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6. MiR-9 promotes tumorigenesis and angiogenesis and is activated by MYC and OCT4 in human glioma.
Chen X; Yang F; Zhang T; Wang W; Xi W; Li Y; Zhang D; Huo Y; Zhang J; Yang A; Wang T
J Exp Clin Cancer Res; 2019 Feb; 38(1):99. PubMed ID: 30795814
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7. Medulloblastoma, WNT-activated/SHH-activated: clinical impact of molecular analysis and histogenetic evaluation.
Cambruzzi E
Childs Nerv Syst; 2018 May; 34(5):809-815. PubMed ID: 29582169
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8. Molecular characterization of medulloblastomas with extensive nodularity (MBEN).
Korshunov A; Sahm F; Stichel D; Schrimpf D; Ryzhova M; Zheludkova O; Golanov A; Lichter P; Jones DTW; von Deimling A; Pfister SM; Kool M
Acta Neuropathol; 2018 Aug; 136(2):303-313. PubMed ID: 29569031
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9. Germline SUFU mutation carriers and medulloblastoma: clinical characteristics, cancer risk, and prognosis.
Guerrini-Rousseau L; Dufour C; Varlet P; Masliah-Planchon J; Bourdeaut F; Guillaud-Bataille M; Abbas R; Bertozzi AI; Fouyssac F; Huybrechts S; Puget S; Bressac-De Paillerets B; Caron O; Sevenet N; Dimaria M; Villebasse S; Delattre O; Valteau-Couanet D; Grill J; Brugières L
Neuro Oncol; 2018 Jul; 20(8):1122-1132. PubMed ID: 29186568
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10. Negative prognostic effect of low nuclear GLI1 expression in glioblastomas.
Kim Y; Do IG; Hong M; Suh YL
J Neurooncol; 2017 May; 133(1):69-76. PubMed ID: 28417299
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11. Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy.
Paret C; Theruvath J; Russo A; Kron B; El Malki K; Lehmann N; Wingerter A; Neu MA; Gerhold-Ay A; Wagner W; Sommer C; Pietsch T; Seidmann L; Faber J
Oncotarget; 2016 Dec; 7(50):83378-83391. PubMed ID: 27825128
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12. The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma.
Andrade AF; Borges KS; Suazo VK; Geron L; Corrêa CA; Castro-Gamero AM; de Vasconcelos EJ; de Oliveira RS; Neder L; Yunes JA; Dos Santos Aguiar S; Scrideli CA; Tone LG
Invest New Drugs; 2017 Feb; 35(1):26-36. PubMed ID: 27785591
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13. Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial.
Clifford SC; Lannering B; Schwalbe EC; Hicks D; O'Toole K; Nicholson SL; Goschzik T; Zur Mühlen A; Figarella-Branger D; Doz F; Rutkowski S; Gustafsson G; Pietsch T;
Oncotarget; 2015 Nov; 6(36):38827-39. PubMed ID: 26420814
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14. Canonical TGF-β pathway activity is a predictor of SHH-driven medulloblastoma survival and delineates putative precursors in cerebellar development.
Aref D; Moffatt CJ; Agnihotri S; Ramaswamy V; Dubuc AM; Northcott PA; Taylor MD; Perry A; Olson JM; Eberhart CG; Croul SE
Brain Pathol; 2013 Mar; 23(2):178-91. PubMed ID: 22966790
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15. Dissecting the genomic complexity underlying medulloblastoma.
Jones DT; Jäger N; Kool M; Zichner T; Hutter B; Sultan M; Cho YJ; Pugh TJ; Hovestadt V; Stütz AM; Rausch T; Warnatz HJ; Ryzhova M; Bender S; Sturm D; Pleier S; Cin H; Pfaff E; Sieber L; Wittmann A; Remke M; Witt H; Hutter S; Tzaridis T; Weischenfeldt J; Raeder B; Avci M; Amstislavskiy V; Zapatka M; Weber UD; Wang Q; Lasitschka B; Bartholomae CC; Schmidt M; von Kalle C; Ast V; Lawerenz C; Eils J; Kabbe R; Benes V; van Sluis P; Koster J; Volckmann R; Shih D; Betts MJ; Russell RB; Coco S; Tonini GP; Schüller U; Hans V; Graf N; Kim YJ; Monoranu C; Roggendorf W; Unterberg A; Herold-Mende C; Milde T; Kulozik AE; von Deimling A; Witt O; Maass E; Rössler J; Ebinger M; Schuhmann MU; Frühwald MC; Hasselblatt M; Jabado N; Rutkowski S; von Bueren AO; Williamson D; Clifford SC; McCabe MG; Collins VP; Wolf S; Wiemann S; Lehrach H; Brors B; Scheurlen W; Felsberg J; Reifenberger G; Northcott PA; Taylor MD; Meyerson M; Pomeroy SL; Yaspo ML; Korbel JO; Korshunov A; Eils R; Pfister SM; Lichter P
Nature; 2012 Aug; 488(7409):100-5. PubMed ID: 22832583
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16. The Hedgehog signalling pathway and its prognostic impact in human gliomas.
Li Q; Zhang Y; Zhan H; Yuan Z; Lu P; Zhan L; Xu W
ANZ J Surg; 2011 Jun; 81(6):440-5. PubMed ID: 22295347
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17. Rapid diagnosis of medulloblastoma molecular subgroups.
Schwalbe EC; Lindsey JC; Straughton D; Hogg TL; Cole M; Megahed H; Ryan SL; Lusher ME; Taylor MD; Gilbertson RJ; Ellison DW; Bailey S; Clifford SC
Clin Cancer Res; 2011 Apr; 17(7):1883-94. PubMed ID: 21325292
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18. Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.
Kool M; Koster J; Bunt J; Hasselt NE; Lakeman A; van Sluis P; Troost D; Meeteren NS; Caron HN; Cloos J; Mrsić A; Ylstra B; Grajkowska W; Hartmann W; Pietsch T; Ellison D; Clifford SC; Versteeg R
PLoS One; 2008 Aug; 3(8):e3088. PubMed ID: 18769486
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19. Detection of genetic and chromosomal aberrations in medulloblastomas and primitive neuroectodermal tumors with DNA microarrays.
Kagawa N; Maruno M; Suzuki T; Hashiba T; Hashimoto N; Izumoto S; Yoshimine T
Brain Tumor Pathol; 2006 Apr; 23(1):41-7. PubMed ID: 18095118
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20. Genetic and expression profiles of cerebellar liponeurocytomas.
Horstmann S; Perry A; Reifenberger G; Giangaspero F; Huang H; Hara A; Masuoka J; Rainov NG; Bergmann M; Heppner FL; Brandner S; Chimelli L; Montagna N; Jackson T; Davis DG; Markesbery WR; Ellison DW; Weller RO; Taddei GL; Conti R; Del Bigio MR; González-Cámpora R; Radhakrishnan VV; Söylemezoglu F; Uro-Coste E; Qian J; Kleihues P; Ohgaki H
Brain Pathol; 2004 Jul; 14(3):281-9. PubMed ID: 15446583
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