BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND PTEN, MMAC1, 5728, MGC11227, PTEN1, MHAM, P60484, BZS, ENSG00000171862 AND Clinical Outcome
20 results:

  • 1. Methylation subgroup and molecular heterogeneity is a hallmark of glioblastoma: implications for biopsy targeting, classification and therapy.
    Gempt J; Withake F; Aftahy AK; Meyer HS; Barz M; Delbridge C; Liesche-Starnecker F; Prokop G; Pfarr N; Schlegel J; Meyer B; Zimmer C; Menze BH; Wiestler B
    ESMO Open; 2022 Oct; 7(5):100566. PubMed ID: 36055049
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Genetic and epigenetic characterization of posterior pituitary tumors.
    Schmid S; Solomon DA; Perez E; Thieme A; Kleinschmidt-DeMasters BK; Giannini C; Reinhardt A; Asa SL; Mete O; Stichel D; Siewert C; Dittmayer C; Hasselblatt M; Paulus W; Nagel C; Harter PN; Schittenhelm J; Honegger J; Rushing E; Coras R; Pfister SM; Buslei R; Koch A; Perry A; Jones DTW; von Deimling A; Capper D; Lopes MB
    Acta Neuropathol; 2021 Dec; 142(6):1025-1043. PubMed ID: 34661724
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Expression of GNAS, TP53, and pten Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup.
    da Silva LS; Mançano BM; de Paula FE; Dos Reis MB; de Almeida GC; Matsushita M; Junior CA; Evangelista AF; Saggioro F; Serafini LN; Stavale JN; Malheiros SMF; Lima M; Hajj GNM; de Lima MA; Taylor MD; Leal LF; Reis RM
    J Mol Diagn; 2020 Jul; 22(7):957-966. PubMed ID: 32380172
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Prognostic value of NUSAP1 in progression and expansion of glioblastoma multiforme.
    Qian Z; Li Y; Ma J; Xue Y; Xi Y; Hong L; Dai X; Zhang Y; Ji X; Chen Y; Sheng M; Sheng Y; Yang L; Liu J; Dai X; Shi J; Xie T; Dong J
    J Neurooncol; 2018 Nov; 140(2):199-208. PubMed ID: 29995176
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and pten: new opportunities for selected targeted therapies.
    Peixoto P; Blomme A; Costanza B; Ronca R; Rezzola S; Palacios AP; Schoysman L; Boutry S; Goffart N; Peulen O; Maris P; Di Valentin E; Hennequière V; Bianchi E; Henry A; Meunier P; Rogister B; Muller RN; Delvenne P; Bellahcène A; Castronovo V; Turtoi A
    Oncogene; 2016 Aug; 35(34):4481-94. PubMed ID: 26853466
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma.
    Meng D; Chen Y; Yun D; Zhao Y; Wang J; Xu T; Li X; Wang Y; Yuan L; Sun R; Song X; Huai C; Hu L; Yang S; Min T; Chen J; Chen H; Lu D
    Oncotarget; 2015 Mar; 6(7):4901-19. PubMed ID: 25669971
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Phase II study of PX-866 in recurrent glioblastoma.
    Pitz MW; Eisenhauer EA; MacNeil MV; Thiessen B; Easaw JC; Macdonald DR; Eisenstat DD; Kakumanu AS; Salim M; Chalchal H; Squire J; Tsao MS; Kamel-Reid S; Banerji S; Tu D; Powers J; Hausman DF; Mason WP
    Neuro Oncol; 2015 Sep; 17(9):1270-4. PubMed ID: 25605819
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Expression and prognostic significance of TCTN1 in human glioblastoma.
    Meng D; Chen Y; Zhao Y; Wang J; Yun D; Yang S; Chen J; Chen H; Lu D
    J Transl Med; 2014 Oct; 12():288. PubMed ID: 25304031
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma.
    Wachsberger PR; Lawrence YR; Liu Y; Rice B; Feo N; Leiby B; Dicker AP
    J Cancer Res Clin Oncol; 2014 Apr; 140(4):573-82. PubMed ID: 24500492
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. pten promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
    Mueller S; Phillips J; Onar-Thomas A; Romero E; Zheng S; Wiencke JK; McBride SM; Cowdrey C; Prados MD; Weiss WA; Berger MS; Gupta N; Haas-Kogan DA
    Neuro Oncol; 2012 Sep; 14(9):1146-52. PubMed ID: 22753230
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Correlation among pathology, genetic and epigenetic profiles, and clinical outcome in oligodendroglial tumors.
    Kuo LT; Kuo KT; Lee MJ; Wei CC; Scaravilli F; Tsai JC; Tseng HM; Kuo MF; Tu YK
    Int J Cancer; 2009 Jun; 124(12):2872-9. PubMed ID: 19330828
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Worse outcome in primary glioblastoma multiforme with concurrent epidermal growth factor receptor and p53 alteration.
    Ruano Y; Ribalta T; de Lope AR; Campos-Martín Y; Fiaño C; Pérez-Magán E; Hernández-Moneo JL; Mollejo M; Meléndez B
    Am J Clin Pathol; 2009 Feb; 131(2):257-63. PubMed ID: 19141386
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Molecular profiling in glioblastoma: prelude to personalized treatment.
    Mladkova N; Chakravarti A
    Curr Oncol Rep; 2009 Jan; 11(1):53-61. PubMed ID: 19080742
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis.
    Opel D; Westhoff MA; Bender A; Braun V; Debatin KM; Fulda S
    Cancer Res; 2008 Aug; 68(15):6271-80. PubMed ID: 18676851
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Prognostic factors for anaplastic astrocytomas.
    Compostella A; Tosoni A; Blatt V; Franceschi E; Brandes AA
    J Neurooncol; 2007 Feb; 81(3):295-303. PubMed ID: 17001519
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Correlation among pathology, genotype, and patient outcomes in glioblastoma.
    Homma T; Fukushima T; Vaccarella S; Yonekawa Y; Di Patre PL; Franceschi S; Ohgaki H
    J Neuropathol Exp Neurol; 2006 Sep; 65(9):846-54. PubMed ID: 16957578
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Prognosis-related molecular markers in pediatric central nervous system tumors.
    Rickert CH
    J Neuropathol Exp Neurol; 2004 Dec; 63(12):1211-24. PubMed ID: 15624758
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Molecular stratification of diagnostically challenging high-grade gliomas composed of small cells: the utility of fluorescence in situ hybridization.
    Korshunov A; Sycheva R; Golanov A
    Clin Cancer Res; 2004 Dec; 10(23):7820-6. PubMed ID: 15585613
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. pten and DMBT1 homozygous deletion and expression in medulloblastomas and supratentorial primitive neuroectodermal tumors.
    Inda MM; Mercapide J; Muñoz J; Coullin P; Danglot G; Tuñon T; Martínez-Peñuela JM; Rivera JM; Burgos JJ; Bernheim A; Castresana JS
    Oncol Rep; 2004 Dec; 12(6):1341-7. PubMed ID: 15547761
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Severe Lhermitte-Duclos disease with unique germline mutation of pten.
    Sutphen R; Diamond TM; Minton SE; Peacocke M; Tsou HC; Root AW
    Am J Med Genet; 1999 Feb; 82(4):290-3. PubMed ID: 10051160
    [TBL] [Abstract] [Full Text] [Related]  


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