BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C
79 results:

  • 1. Fgf2 and ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia.
    Zhang L; Xu L
    Medicine (Baltimore); 2023 Nov; 102(45):e36108. PubMed ID: 37960778
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. ptpn11 variant may be a prognostic indicator of IDH-wildtype glioblastoma in a comprehensive genomic profiling cohort.
    Otani R; Ikegami M; Yamada R; Yajima H; Kawamura S; Shimizu S; Tanaka S; Takayanagi S; Takami H; Yamaguchi T
    J Neurooncol; 2023 Aug; 164(1):221-229. PubMed ID: 37552362
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
    Wu M; Song D; Li H; Ahmad N; Xu H; Yang X; Wang Q; Cheng X; Deng S; Shu X
    Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298405
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. An integrated genetic analysis of epileptogenic brain malformed lesions.
    Fujita A; Kato M; Sugano H; Iimura Y; Suzuki H; Tohyama J; Fukuda M; Ito Y; Baba S; Okanishi T; Enoki H; Fujimoto A; Yamamoto A; Kawamura K; Kato S; Honda R; Ono T; Shiraishi H; Egawa K; Shirai K; Yamamoto S; Hayakawa I; Kawawaki H; Saida K; Tsuchida N; Uchiyama Y; Hamanaka K; Miyatake S; Mizuguchi T; Nakashima M; Saitsu H; Miyake N; Kakita A; Matsumoto N
    Acta Neuropathol Commun; 2023 Mar; 11(1):33. PubMed ID: 36864519
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The genomic landscape across 474 surgically accessible epileptogenic human brain lesions.
    López-Rivera JA; Leu C; Macnee M; Khoury J; Hoffmann L; Coras R; Kobow K; Bhattarai N; Pérez-Palma E; Hamer H; Brandner S; Rössler K; Bien CG; Kalbhenn T; Pieper T; Hartlieb T; Butler E; Genovese G; Becker K; Altmüller J; Niestroj LM; Ferguson L; Busch RM; Nürnberg P; Najm I; Blümcke I; Lal D
    Brain; 2023 Apr; 146(4):1342-1356. PubMed ID: 36226386
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. H3K27M-Altered Diffuse Midline Gliomas Among Adult Patients: A Systematic Review of Clinical Features and Survival Analysis.
    Bin-Alamer O; Jimenez AE; Azad TD; Bettegowda C; Mukherjee D
    World Neurosurg; 2022 Sep; 165():e251-e264. PubMed ID: 35697228
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Thoracic low grade glial neoplasm with concurrent H3 K27M and ptpn11 mutations.
    Argenziano MG; Furnari JL; Miller ML; Sun Y; Banu MA; Neira JA; Snuderl M; Bruce JN; Welch M; McCormick P; Canoll P
    Acta Neuropathol Commun; 2022 Apr; 10(1):64. PubMed ID: 35484611
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Structure-based discovery of a specific shp2 inhibitor with enhanced blood-brain barrier penetration from PubChem database.
    Ma Y; Li WY; Sun T; Zhang L; Lu XH; Yang B; Wang RL
    Bioorg Chem; 2022 Apr; 121():105648. PubMed ID: 35180489
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma.
    Arrieta VA; Chen AX; Kane JR; Kang SJ; Kassab C; Dmello C; Zhao J; Burdett KB; Upadhyayula PS; Lee-Chang C; Shilati J; Jaishankar D; Chen L; Gould A; Zhang D; Yuan J; Zhao W; Ling X; Burks JK; Laffleur B; Amidei C; Bruce JN; Lukas RV; Yamaguchi JT; Cieremans D; Rothschild G; Basu U; McCord M; Brat DJ; Zhang H; Cooper LAD; Zhang B; Sims P; Cloughesy TF; Prins R; Canoll P; Stupp R; Heimberger AB; Horbinski C; Iwamoto FM; Rabadan R; Sonabend AM
    Nat Cancer; 2021 Dec; 2(12):1372-1386. PubMed ID: 35121903
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Deciphering the Role of Extracellular Vesicles Derived from ZIKV-Infected hcMEC/D3 Cells on the Blood-brain Barrier System.
    Fikatas A; Dehairs J; Noppen S; Doijen J; Vanderhoydonc F; Meyen E; Swinnen JV; Pannecouque C; Schols D
    Viruses; 2021 Nov; 13(12):. PubMed ID: 34960632
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Rosette-Forming Glioneuronal Tumor in the Pineal Region: A Series of 6 Cases and Literature Review.
    Lin CC; Mansukhani MM; Bruce JN; Canoll P; Zanazzi G
    J Neuropathol Exp Neurol; 2021 Oct; 80(10):933-943. PubMed ID: 34498065
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations.
    Gil-Ranedo J; Gallego-García C; Almendral JM
    Cell Rep; 2021 Sep; 36(10):109673. PubMed ID: 34496248
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Clinical variability of neurofibromatosis 1: A modifying role of cooccurring ptpn11 variants and atypical brain MRI findings.
    D'Amico A; Rosano C; Pannone L; Pinna V; Assunto A; Motta M; Ugga L; Daniele P; Mandile R; Mariniello L; Siano MA; Santoro C; Piluso G; Martinelli S; Strisciuglio P; De Luca A; Tartaglia M; Melis D
    Clin Genet; 2021 Nov; 100(5):563-572. PubMed ID: 34346503
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling.
    Dardis C; Donner D; Sanai N; Xiu J; Mittal S; Michelhaugh SK; Pandey M; Kesari S; Heimberger AB; Gatalica Z; Korn MW; Sumrall AL; Phuphanich S
    BMC Neurol; 2021 Jun; 21(1):231. PubMed ID: 34162346
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
    Suzuki T; Koike Y; Ashikawa K; Otomo N; Takahashi A; Aoi T; Kamatani N; Nakamura Y; Kubo M; Kamatani Y; Momozawa Y; Terao C; Yamakawa K
    Epilepsia; 2021 Jun; 62(6):1391-1400. PubMed ID: 33913524
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Alterations in the Global Proteome and Phosphoproteome in Third Generation EGFR TKI Resistance Reveal Drug Targets to Circumvent Resistance.
    Zhang X; Maity TK; Ross KE; Qi Y; Cultraro CM; Bahta M; Pitts S; Keswani M; Gao S; Nguyen KDP; Cowart J; Kirkali F; Wu C; Guha U
    Cancer Res; 2021 Jun; 81(11):3051-3066. PubMed ID: 33727228
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Proteogenomic and metabolomic characterization of human glioblastoma.
    Wang LB; Karpova A; Gritsenko MA; Kyle JE; Cao S; Li Y; Rykunov D; Colaprico A; Rothstein JH; Hong R; Stathias V; Cornwell M; Petralia F; Wu Y; Reva B; Krug K; Pugliese P; Kawaler E; Olsen LK; Liang WW; Song X; Dou Y; Wendl MC; Caravan W; Liu W; Cui Zhou D; Ji J; Tsai CF; Petyuk VA; Moon J; Ma W; Chu RK; Weitz KK; Moore RJ; Monroe ME; Zhao R; Yang X; Yoo S; Krek A; Demopoulos A; Zhu H; Wyczalkowski MA; McMichael JF; Henderson BL; Lindgren CM; Boekweg H; Lu S; Baral J; Yao L; Stratton KG; Bramer LM; Zink E; Couvillion SP; Bloodsworth KJ; Satpathy S; Sieh W; Boca SM; Schürer S; Chen F; Wiznerowicz M; Ketchum KA; Boja ES; Kinsinger CR; Robles AI; Hiltke T; Thiagarajan M; Nesvizhskii AI; Zhang B; Mani DR; Ceccarelli M; Chen XS; Cottingham SL; Li QK; Kim AH; Fenyö D; Ruggles KV; Rodriguez H; Mesri M; Payne SH; Resnick AC; Wang P; Smith RD; Iavarone A; Chheda MG; Barnholtz-Sloan JS; Rodland KD; Liu T; Ding L;
    Cancer Cell; 2021 Apr; 39(4):509-528.e20. PubMed ID: 33577785
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to shp2 Inhibition.
    Day EK; Zhong Q; Purow B; Lazzara MJ
    Cancer Res; 2021 Apr; 81(8):2056-2070. PubMed ID: 33574084
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
    Hou Y; Sun B; Liu W; Yu B; Shi Q; Luo F; Bai Y; Feng H
    Theranostics; 2021; 11(2):555-566. PubMed ID: 33391492
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Genetic characterization of an aggressive optic nerve pilocytic glioma.
    Hong CS; Fliney G; Fisayo A; An Y; Gopal PP; Omuro A; Pointdujour-Lim R; Erson-Omay EZ; Omay SB
    Brain Tumor Pathol; 2021 Jan; 38(1):59-63. PubMed ID: 33098465
    [TBL] [Abstract] [Full Text] [Related]  


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