BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C AND Treatment
19 results:

  • 1. Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
    Wu M; Song D; Li H; Ahmad N; Xu H; Yang X; Wang Q; Cheng X; Deng S; Shu X
    Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298405
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The genomic landscape across 474 surgically accessible epileptogenic human brain lesions.
    López-Rivera JA; Leu C; Macnee M; Khoury J; Hoffmann L; Coras R; Kobow K; Bhattarai N; Pérez-Palma E; Hamer H; Brandner S; Rössler K; Bien CG; Kalbhenn T; Pieper T; Hartlieb T; Butler E; Genovese G; Becker K; Altmüller J; Niestroj LM; Ferguson L; Busch RM; Nürnberg P; Najm I; Blümcke I; Lal D
    Brain; 2023 Apr; 146(4):1342-1356. PubMed ID: 36226386
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Deciphering the Role of Extracellular Vesicles Derived from ZIKV-Infected hcMEC/D3 Cells on the Blood-brain Barrier System.
    Fikatas A; Dehairs J; Noppen S; Doijen J; Vanderhoydonc F; Meyen E; Swinnen JV; Pannecouque C; Schols D
    Viruses; 2021 Nov; 13(12):. PubMed ID: 34960632
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling.
    Dardis C; Donner D; Sanai N; Xiu J; Mittal S; Michelhaugh SK; Pandey M; Kesari S; Heimberger AB; Gatalica Z; Korn MW; Sumrall AL; Phuphanich S
    BMC Neurol; 2021 Jun; 21(1):231. PubMed ID: 34162346
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Alterations in the Global Proteome and Phosphoproteome in Third Generation EGFR TKI Resistance Reveal Drug Targets to Circumvent Resistance.
    Zhang X; Maity TK; Ross KE; Qi Y; Cultraro CM; Bahta M; Pitts S; Keswani M; Gao S; Nguyen KDP; Cowart J; Kirkali F; Wu C; Guha U
    Cancer Res; 2021 Jun; 81(11):3051-3066. PubMed ID: 33727228
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Proteogenomic and metabolomic characterization of human glioblastoma.
    Wang LB; Karpova A; Gritsenko MA; Kyle JE; Cao S; Li Y; Rykunov D; Colaprico A; Rothstein JH; Hong R; Stathias V; Cornwell M; Petralia F; Wu Y; Reva B; Krug K; Pugliese P; Kawaler E; Olsen LK; Liang WW; Song X; Dou Y; Wendl MC; Caravan W; Liu W; Cui Zhou D; Ji J; Tsai CF; Petyuk VA; Moon J; Ma W; Chu RK; Weitz KK; Moore RJ; Monroe ME; Zhao R; Yang X; Yoo S; Krek A; Demopoulos A; Zhu H; Wyczalkowski MA; McMichael JF; Henderson BL; Lindgren CM; Boekweg H; Lu S; Baral J; Yao L; Stratton KG; Bramer LM; Zink E; Couvillion SP; Bloodsworth KJ; Satpathy S; Sieh W; Boca SM; Schürer S; Chen F; Wiznerowicz M; Ketchum KA; Boja ES; Kinsinger CR; Robles AI; Hiltke T; Thiagarajan M; Nesvizhskii AI; Zhang B; Mani DR; Ceccarelli M; Chen XS; Cottingham SL; Li QK; Kim AH; Fenyö D; Ruggles KV; Rodriguez H; Mesri M; Payne SH; Resnick AC; Wang P; Smith RD; Iavarone A; Chheda MG; Barnholtz-Sloan JS; Rodland KD; Liu T; Ding L;
    Cancer Cell; 2021 Apr; 39(4):509-528.e20. PubMed ID: 33577785
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
    Hou Y; Sun B; Liu W; Yu B; Shi Q; Luo F; Bai Y; Feng H
    Theranostics; 2021; 11(2):555-566. PubMed ID: 33391492
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Newcastle Disease Virus (NDV) Oncolytic Activity in Human Glioma Tumors Is Dependent on CDKN2A-Type I IFN Gene Cluster Codeletion.
    García-Romero N; Palacín-Aliana I; Esteban-Rubio S; Madurga R; Rius-Rocabert S; Carrión-Navarro J; Presa J; Cuadrado-Castano S; Sánchez-Gómez P; García-Sastre A; Nistal-Villan E; Ayuso-Sacido A
    Cells; 2020 Jun; 9(6):. PubMed ID: 32516884
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Next generation sequencing identifies novel potential actionable mutations for grade I meningioma treatment.
    Pepe F; Pisapia P; Del Basso de Caro ML; Conticelli F; Malapelle U; Troncone G; Martinez JC
    Histol Histopathol; 2020 Jul; 35(7):741-749. PubMed ID: 31872418
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Targeting PDGFRα-activated glioblastoma through specific inhibition of shp-2-mediated signaling.
    Sang Y; Hou Y; Cheng R; Zheng L; Alvarez AA; Hu B; Cheng SY; Zhang W; Li Y; Feng H
    Neuro Oncol; 2019 Nov; 21(11):1423-1435. PubMed ID: 31232447
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Zika virus NS5 protein inhibits cell growth and invasion of glioma.
    Li H; Hu Y; Huang J; Feng Y; Zhang Z; Zhong K; Chen Y; Wang Z; Huang C; Yang H; Tong A
    Biochem Biophys Res Commun; 2019 Aug; 516(2):515-520. PubMed ID: 31230744
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma.
    Zhao J; Chen AX; Gartrell RD; Silverman AM; Aparicio L; Chu T; Bordbar D; Shan D; Samanamud J; Mahajan A; Filip I; Orenbuch R; Goetz M; Yamaguchi JT; Cloney M; Horbinski C; Lukas RV; Raizer J; Rae AI; Yuan J; Canoll P; Bruce JN; Saenger YM; Sims P; Iwamoto FM; Sonabend AM; Rabadan R
    Nat Med; 2019 Mar; 25(3):462-469. PubMed ID: 30742119
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Trametinib for progressive pediatric low-grade gliomas.
    Kondyli M; Larouche V; Saint-Martin C; Ellezam B; Pouliot L; Sinnett D; Legault G; Crevier L; Weil A; Farmer JP; Jabado N; Perreault S
    J Neurooncol; 2018 Nov; 140(2):435-444. PubMed ID: 30097824
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. [Oncolytic potential of recombinant influenza A virus vectors on a model of malignant glioma in vivo].
    Shurygina APS; Kartashev AV; Kovanko EG; Kiseleva LN; Pustovalov YI; Slita AK; Zarubaev VV; Belyaevskaya SV; Sirotkin AK; Kiselev OI; Egorov AY
    Vopr Onkol; 2016; 62(1):138-45. PubMed ID: 30444592
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome.
    Lee YS; Ehninger D; Zhou M; Oh JY; Kang M; Kwak C; Ryu HH; Butz D; Araki T; Cai Y; Balaji J; Sano Y; Nam CI; Kim HK; Kaang BK; Burger C; Neel BG; Silva AJ
    Nat Neurosci; 2014 Dec; 17(12):1736-43. PubMed ID: 25383899
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. shp-2/ptpn11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans.
    Liu KW; Feng H; Bachoo R; Kazlauskas A; Smith EM; Symes K; Hamilton RL; Nagane M; Nishikawa R; Hu B; Cheng SY
    J Clin Invest; 2011 Mar; 121(3):905-17. PubMed ID: 21393858
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Protein tyrosine phosphatases in glioma biology.
    Navis AC; van den Eijnden M; Schepens JT; Hooft van Huijsduijnen R; Wesseling P; Hendriks WJ
    Acta Neuropathol; 2010 Feb; 119(2):157-75. PubMed ID: 19936768
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. shp-2-dependent mitogen-activated protein kinase activation regulates EGFRvIII but not wild-type epidermal growth factor receptor phosphorylation and glioblastoma cell survival.
    Zhan Y; O'Rourke DM
    Cancer Res; 2004 Nov; 64(22):8292-8. PubMed ID: 15548697
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The effect of DFMO induced uptake of [3H] putrescine on human glioma cells.
    Redgate ES; Alexander D; Magra TR; Henretty JS; Patrene KD; Boggs SS
    J Neurooncol; 2001 Nov; 55(2):71-80. PubMed ID: 11817704
    [TBL] [Abstract] [Full Text] [Related]  


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