BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND QKI, Hqk, 9444, ENSG00000112531, Q96PU8, QK3, DKFZp586I0923, QK
27 results:

  • 1. Case Report: brainstem angiocentric glioma presenting in a toddler child-diagnostic and therapeutic challenges.
    Reisz Z; Radics BL; Nemes P; Laxton R; Kaizer L; Gabor KM; Novak T; Barzo P; Al-Sarraj S; Bodi I
    Pathol Oncol Res; 2023; 29():1611231. PubMed ID: 37362245
    [No Abstract]    [Full Text] [Related]  

  • 2. DIPG-like MYB-altered diffuse astrocytoma with durable response to intensive chemotherapy.
    Trkova K; Sumerauer D; Krskova L; Vicha A; Koblizek M; Votava T; Priban V; Zapotocky M
    Childs Nerv Syst; 2023 Sep; 39(9):2509-2513. PubMed ID: 37165121
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Lorlatinib for ALK-fused, infant-type hemispheric glioma with lung metastasis: a case report.
    Lai M; Li S; Li H; Hu Q; Li J; Zhou J; Ai R; Zhen J; Zhou Z; Wang L; Zhang Y; Hu W; Yuan L; Ma X; Zhang X; Song C; Li Z; Cai L
    Ann Clin Transl Neurol; 2023 May; 10(5):836-841. PubMed ID: 37000961
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. MYB/MYBL1::qki fusion-positive diffuse glioma.
    Suh YY; Lee K; Shim YM; Phi JH; Park CK; Kim SK; Choi SH; Yun H; Park SH
    J Neuropathol Exp Neurol; 2023 Feb; 82(3):250-260. PubMed ID: 36592415
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. qki deficiency in macrophages protects mice against JEV infection by regulating cell migration and antiviral response.
    Deng L; Wang W; Bian P; Wu M; Wang L; Lei Y; Lu Z; Zhai D
    Mol Immunol; 2022 Aug; 148():34-44. PubMed ID: 35665659
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Immune landscape of a genetically engineered murine model of glioma compared with human glioma.
    Zamler DB; Shingu T; Kahn LM; Huntoon K; Kassab C; Ott M; Tomczak K; Liu J; Li Y; Lai I; Zorilla-Veloz R; Yee C; Rai K; Kim BY; Watowich SS; Heimberger AB; Draetta GF; Hu J
    JCI Insight; 2022 Jun; 7(12):. PubMed ID: 35653194
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Angiocentric glioma: A case report and review of the literature.
    Wang H; Zhu J; Zhu P; Luo C
    J Clin Neurosci; 2021 Dec; 94():179-185. PubMed ID: 34863434
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Ambient carbon monoxide exposure and elevated risk of mortality in the glioblastoma patients: A double-cohort retrospective observational study.
    Yoon SJ; Noh J; Son HY; Moon JH; Kim EH; Park SW; Kim SH; Chang JH; Huh YM; Kang SG
    Cancer Med; 2020 Dec; 9(23):9018-9026. PubMed ID: 33161654
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [Low grade glioma with MYBL1 alteration: Case report of an uncommon pediatric neoplasm].
    Appay R; Tauziède-Espariat A; Silva K; Fritih R; Scavarda D; Delteil C; Varlet P; Figarella-Branger D
    Ann Pathol; 2021 Feb; 41(1):129-133. PubMed ID: 32732147
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
    Lake JA; Donson AM; Prince E; Davies KD; Nellan A; Green AL; Mulcahy Levy J; Dorris K; Vibhakar R; Hankinson TC; Foreman NK; Ewalt MD; Kleinschmidt-DeMasters BK; Hoffman LM; Gilani A
    Pediatr Blood Cancer; 2020 Jan; 67(1):e28028. PubMed ID: 31595628
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. qki deficiency maintains glioma stem cell stemness by activating the SHH/GLI1 signaling pathway.
    Han B; Wang R; Chen Y; Meng X; Wu P; Li Z; Duan C; Li Q; Li Y; Zhao S; Jiang C; Cai J
    Cell Oncol (Dordr); 2019 Dec; 42(6):801-813. PubMed ID: 31292920
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.
    Oldrini B; Curiel-García Á; Marques C; Matia V; Uluçkan Ö; Graña-Castro O; Torres-Ruiz R; Rodriguez-Perales S; Huse JT; Squatrito M
    Nat Commun; 2018 Apr; 9(1):1466. PubMed ID: 29654229
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases.
    Shah N; Mohammad AS; Saralkar P; Sprowls SA; Vickers SD; John D; Tallman RM; Lucke-Wold BP; Jarrell KE; Pinti M; Nolan RL; Lockman PR
    Pharmacol Res; 2018 Jun; 132():47-68. PubMed ID: 29604436
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures.
    Johnson A; Severson E; Gay L; Vergilio JA; Elvin J; Suh J; Daniel S; Covert M; Frampton GM; Hsu S; Lesser GJ; Stogner-Underwood K; Mott RT; Rush SZ; Stanke JJ; Dahiya S; Sun J; Reddy P; Chalmers ZR; Erlich R; Chudnovsky Y; Fabrizio D; Schrock AB; Ali S; Miller V; Stephens PJ; Ross J; Crawford JR; Ramkissoon SH
    Oncologist; 2017 Dec; 22(12):1478-1490. PubMed ID: 28912153
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Copy number alterations determined by single nucleotide polymorphism array testing in the clinical laboratory are indicative of gene fusions in pediatric cancer patients.
    Busse TM; Roth JJ; Wilmoth D; Wainwright L; Tooke L; Biegel JA
    Genes Chromosomes Cancer; 2017 Oct; 56(10):730-749. PubMed ID: 28597942
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Overexpression of miR-29a reduces the oncogenic properties of glioblastoma stem cells by downregulating Quaking gene isoform 6.
    Xi Z; Wang P; Xue Y; Shang C; Liu X; Ma J; Li Z; Li Z; Bao M; Liu Y
    Oncotarget; 2017 Apr; 8(15):24949-24963. PubMed ID: 28212562
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.
    Ramkissoon SH; Bandopadhayay P; Hwang J; Ramkissoon LA; Greenwald NF; Schumacher SE; O'Rourke R; Pinches N; Ho P; Malkin H; Sinai C; Filbin M; Plant A; Bi WL; Chang MS; Yang E; Wright KD; Manley PE; Ducar M; Alexandrescu S; Lidov H; Delalle I; Goumnerova LC; Church AJ; Janeway KA; Harris MH; MacConaill LE; Folkerth RD; Lindeman NI; Stiles CD; Kieran MW; Ligon AH; Santagata S; Dubuc AM; Chi SN; Beroukhim R; Ligon KL
    Neuro Oncol; 2017 Jul; 19(7):986-996. PubMed ID: 28104717
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Tyrosine receptor kinase B is a drug target in astrocytomas.
    Ni J; Xie S; Ramkissoon SH; Luu V; Sun Y; Bandopadhayay P; Beroukhim R; Roberts TM; Stiles CD; Segal RA; Ligon KL; Hahn WC; Zhao JJ
    Neuro Oncol; 2017 Jan; 19(1):22-30. PubMed ID: 27402815
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. MYB-qki rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.
    Bandopadhayay P; Ramkissoon LA; Jain P; Bergthold G; Wala J; Zeid R; Schumacher SE; Urbanski L; O'Rourke R; Gibson WJ; Pelton K; Ramkissoon SH; Han HJ; Zhu Y; Choudhari N; Silva A; Boucher K; Henn RE; Kang YJ; Knoff D; Paolella BR; Gladden-Young A; Varlet P; Pages M; Horowitz PM; Federation A; Malkin H; Tracy AA; Seepo S; Ducar M; Van Hummelen P; Santi M; Buccoliero AM; Scagnet M; Bowers DC; Giannini C; Puget S; Hawkins C; Tabori U; Klekner A; Bognar L; Burger PC; Eberhart C; Rodriguez FJ; Hill DA; Mueller S; Haas-Kogan DA; Phillips JJ; Santagata S; Stiles CD; Bradner JE; Jabado N; Goren A; Grill J; Ligon AH; Goumnerova L; Waanders AJ; Storm PB; Kieran MW; Ligon KL; Beroukhim R; Resnick AC
    Nat Genet; 2016 Mar; 48(3):273-82. PubMed ID: 26829751
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.
    Qaddoumi I; Orisme W; Wen J; Santiago T; Gupta K; Dalton JD; Tang B; Haupfear K; Punchihewa C; Easton J; Mulder H; Boggs K; Shao Y; Rusch M; Becksfort J; Gupta P; Wang S; Lee RP; Brat D; Peter Collins V; Dahiya S; George D; Konomos W; Kurian KM; McFadden K; Serafini LN; Nickols H; Perry A; Shurtleff S; Gajjar A; Boop FA; Klimo PD; Mardis ER; Wilson RK; Baker SJ; Zhang J; Wu G; Downing JR; Tatevossian RG; Ellison DW
    Acta Neuropathol; 2016 Jun; 131(6):833-45. PubMed ID: 26810070
    [TBL] [Abstract] [Full Text] [Related]  


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