Terms: = Brain cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25
139 results:
1. GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress.
Zhou W; Zhao Z; Lin A; Yang JZ; Xu J; Wilder-Romans K; Yang A; Li J; Solanki S; Speth JM; Walker N; Scott AJ; Wang L; Wen B; Andren A; Zhang L; Kothari AU; Yao Y; Peterson ER; Korimerla N; Werner CK; Ullrich A; Liang J; Jacobson J; Palavalasa S; O'Brien AM; Elaimy AL; Ferris SP; Zhao SG; Sarkaria JN; Győrffy B; Zhang S; Al-Holou WN; Umemura Y; Morgan MA; Lawrence TS; Lyssiotis CA; Peters-Golden M; Shah YM; Wahl DR
Cancer Discov; 2024 Jan; 14(1):158-175. PubMed ID: 37902550
[TBL] [Abstract] [Full Text] [Related]
2. Neuronal actin cytoskeleton gain of function in the human brain.
Szigeti K; Ihnatovych I; Rosas N; Dorn RP; Notari E; Cortes Gomez E; He M; Maly I; Prasad S; Nimmer E; Heo Y; Fuchsova B; Bennett DA; Hofmann WA; Pralle A; Bae Y; Wang J
EBioMedicine; 2023 Sep; 95():104725. PubMed ID: 37517100
[TBL] [Abstract] [Full Text] [Related]
3. Identification of rac1 in promoting brain metastasis of lung adenocarcinoma using single-cell transcriptome sequencing.
Chen M; Li H; Xu X; Bao X; Xue L; Ai X; Xu J; Xu M; Shi Y; Zhen T; Li J; Yang Y; Ji Y; Fu Z; Xing K; Qing T; Wang Q; Zhong P; Zhu S
Cell Death Dis; 2023 May; 14(5):330. PubMed ID: 37202394
[TBL] [Abstract] [Full Text] [Related]
4. Sema3C signaling is an alternative activator of the canonical WNT pathway in glioblastoma.
Hao J; Han X; Huang H; Yu X; Fang J; Zhao J; Prayson RA; Bao S; Yu JS
Nat Commun; 2023 Apr; 14(1):2262. PubMed ID: 37080989
[TBL] [Abstract] [Full Text] [Related]
5. SAMHD1-induced endosomal FAK signaling promotes human renal clear cell carcinoma metastasis by activating rac1-mediated lamellipodia protrusion.
An S; Vo TTL; Son T; Choi H; Kim J; Lee J; Kim BH; Choe M; Ha E; Surh YJ; Kim KW; Seo JH
Exp Mol Med; 2023 Apr; 55(4):779-793. PubMed ID: 37009792
[TBL] [Abstract] [Full Text] [Related]
6. Beyond Warburg: LDHA activates RAC for tumour growth.
Osaka N; Sasaki AT
Nat Metab; 2022 Dec; 4(12):1623-1625. PubMed ID: 36536138
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7. The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on rac1 level and migration of medulloblastoma in vitro.
Schoen LF; Craveiro RB; Pietsch T; Moritz T; Troeger A; Jordans S; Dilloo D
J Cell Mol Med; 2022 Dec; 26(23):5832-5845. PubMed ID: 36377725
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8. A distinct pattern of growth and rac1 signaling in melanoma brain metastasis cells.
Stejerean-Todoran I; Gimotty PA; Watters A; Brafford P; Krepler C; Godok T; Li H; Bonilla Del Rio Z; Zieseniss A; Katschinski DM; Sertel SM; Rizzoli SO; Garman B; Nathanson KL; Xu X; Chen Q; Oswald JH; Lotem M; Mills GB; Davies MA; Schön MP; Bogeski I; Herlyn M; Vultur A
Neuro Oncol; 2023 Apr; 25(4):674-686. PubMed ID: 36054930
[TBL] [Abstract] [Full Text] [Related]
9. Induction of rac1 protein translation and MKK7/JNK-dependent autophagy through dicer/miR-145/SOX2/miR-365a axis contributes to isorhapontigenin (ISO) inhibition of human bladder cancer invasion.
Hua X; Xiang D; Guo M; Qian X; Chen R; Li T; Tian Z; Xu J; Huang C; Xie Q; Huang C
Cell Death Dis; 2022 Aug; 13(8):753. PubMed ID: 36045117
[TBL] [Abstract] [Full Text] [Related]
10. Reduced miR-371b-5p expression drives tumor progression via CSDE1/rac1 regulation in triple-negative breast cancer.
Kim Y; Ko JY; Lee SB; Oh S; Park JW; Kang HG; Kim DH; Chung D; Lim S; Kong H; Kim J; Yoo KH; Han W; Chun KH; Park JH
Oncogene; 2022 May; 41(22):3151-3161. PubMed ID: 35490208
[TBL] [Abstract] [Full Text] [Related]
11. The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.
Karachaliou GS; Alkallas R; Carroll SB; Caressi C; Zakria D; Patel NM; Trembath DG; Ezzell JA; Pegna GJ; Googe PB; Galeotti JP; Ayvali F; Collichio FA; Lee CB; Ollila DW; Gulley ML; Johnson DB; Kim KB; Watson IR; Moschos SJ
BMC Cancer; 2022 Jan; 22(1):38. PubMed ID: 34986841
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12. The brain-derived neurotrophic factor prompts platelet aggregation and secretion.
Boukhatem I; Fleury S; Welman M; Le Blanc J; Thys C; Freson K; Best MG; Würdinger T; Allen BG; Lordkipanidzé M
Blood Adv; 2021 Sep; 5(18):3568-3580. PubMed ID: 34546355
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13. RAB1A regulates glioma cellular proliferation and invasion via the mTOR signaling pathway and epithelial-mesenchymal transition.
Ren B; Wang L; Nan Y; Liu T; Zhao L; Ma H; Li J; Zhang Y; Ren X
Future Oncol; 2021 Aug; 17(24):3203-3216. PubMed ID: 33947216
[No Abstract] [Full Text] [Related]
14. Molecular Mechanisms of the Blockage of Glioblastoma Motility.
Xu J; Simonelli F; Li X; Spinello A; Laporte S; Torre V; Magistrato A
J Chem Inf Model; 2021 Jun; 61(6):2967-2980. PubMed ID: 33861592
[TBL] [Abstract] [Full Text] [Related]
15. Glioma-Derived TSP2 Promotes Excitatory Synapse Formation and Results in Hyperexcitability in the Peritumoral Cortex of Glioma.
Wang YH; Huang TL; Chen X; Yu SX; Li W; Chen T; Li Y; Kuang YQ; Shu HF
J Neuropathol Exp Neurol; 2021 Jan; 80(2):137-149. PubMed ID: 33382873
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16. Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells.
Kolodziej MA; Al Barim B; Nagl J; Weigand MA; Uhl E; Uhle F; Di Fazio P; Schwarm FP; Stein M
Int J Oncol; 2020 Oct; 57(4):1039-1046. PubMed ID: 32945397
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17. Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics.
Wang M; Jiang X; Yang Y; Chen H; Zhang C; Xu H; Qi B; Yao C; Xia H
Neurotherapeutics; 2020 Oct; 17(4):2028-2040. PubMed ID: 32822001
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18. Bioinformatic analysis of the potential molecular mechanism of PAK7 expression in glioblastoma.
Wang X; Liu S; Shao Z; Zhang P
Mol Med Rep; 2020 Aug; 22(2):1362-1372. PubMed ID: 32626960
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19. Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Feng X; Zhang H; Meng L; Song H; Zhou Q; Qu C; Zhao P; Li Q; Zou C; Liu X; Zhang Z
Autophagy; 2021 Mar; 17(3):723-742. PubMed ID: 32186433
[TBL] [Abstract] [Full Text] [Related]
20. Opposite Modulation of rac1 by Mutations in TRIO Is Associated with Distinct, Domain-Specific Neurodevelopmental Disorders.
Barbosa S; Greville-Heygate S; Bonnet M; Godwin A; Fagotto-Kaufmann C; Kajava AV; Laouteouet D; Mawby R; Wai HA; Dingemans AJM; Hehir-Kwa J; Willems M; Capri Y; Mehta SG; Cox H; Goudie D; Vansenne F; Turnpenny P; Vincent M; Cogné B; Lesca G; Hertecant J; Rodriguez D; Keren B; Burglen L; Gérard M; Putoux A; ; Cantagrel V; Siquier-Pernet K; Rio M; Banka S; Sarkar A; Steeves M; Parker M; Clement E; Moutton S; Tran Mau-Them F; Piton A; de Vries BBA; Guille M; Debant A; Schmidt S; Baralle D
Am J Hum Genet; 2020 Mar; 106(3):338-355. PubMed ID: 32109419
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