Terms: = Brain cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
36 results:
1. GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress.
Zhou W; Zhao Z; Lin A; Yang JZ; Xu J; Wilder-Romans K; Yang A; Li J; Solanki S; Speth JM; Walker N; Scott AJ; Wang L; Wen B; Andren A; Zhang L; Kothari AU; Yao Y; Peterson ER; Korimerla N; Werner CK; Ullrich A; Liang J; Jacobson J; Palavalasa S; O'Brien AM; Elaimy AL; Ferris SP; Zhao SG; Sarkaria JN; Győrffy B; Zhang S; Al-Holou WN; Umemura Y; Morgan MA; Lawrence TS; Lyssiotis CA; Peters-Golden M; Shah YM; Wahl DR
Cancer Discov; 2024 Jan; 14(1):158-175. PubMed ID: 37902550
[TBL] [Abstract] [Full Text] [Related]
2. The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on rac1 level and migration of medulloblastoma in vitro.
Schoen LF; Craveiro RB; Pietsch T; Moritz T; Troeger A; Jordans S; Dilloo D
J Cell Mol Med; 2022 Dec; 26(23):5832-5845. PubMed ID: 36377725
[TBL] [Abstract] [Full Text] [Related]
3. A distinct pattern of growth and rac1 signaling in melanoma brain metastasis cells.
Stejerean-Todoran I; Gimotty PA; Watters A; Brafford P; Krepler C; Godok T; Li H; Bonilla Del Rio Z; Zieseniss A; Katschinski DM; Sertel SM; Rizzoli SO; Garman B; Nathanson KL; Xu X; Chen Q; Oswald JH; Lotem M; Mills GB; Davies MA; Schön MP; Bogeski I; Herlyn M; Vultur A
Neuro Oncol; 2023 Apr; 25(4):674-686. PubMed ID: 36054930
[TBL] [Abstract] [Full Text] [Related]
4. Induction of rac1 protein translation and MKK7/JNK-dependent autophagy through dicer/miR-145/SOX2/miR-365a axis contributes to isorhapontigenin (ISO) inhibition of human bladder cancer invasion.
Hua X; Xiang D; Guo M; Qian X; Chen R; Li T; Tian Z; Xu J; Huang C; Xie Q; Huang C
Cell Death Dis; 2022 Aug; 13(8):753. PubMed ID: 36045117
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5. Glioma-Derived TSP2 Promotes Excitatory Synapse Formation and Results in Hyperexcitability in the Peritumoral Cortex of Glioma.
Wang YH; Huang TL; Chen X; Yu SX; Li W; Chen T; Li Y; Kuang YQ; Shu HF
J Neuropathol Exp Neurol; 2021 Jan; 80(2):137-149. PubMed ID: 33382873
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6. Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells.
Kolodziej MA; Al Barim B; Nagl J; Weigand MA; Uhl E; Uhle F; Di Fazio P; Schwarm FP; Stein M
Int J Oncol; 2020 Oct; 57(4):1039-1046. PubMed ID: 32945397
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7. Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics.
Wang M; Jiang X; Yang Y; Chen H; Zhang C; Xu H; Qi B; Yao C; Xia H
Neurotherapeutics; 2020 Oct; 17(4):2028-2040. PubMed ID: 32822001
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8. Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Feng X; Zhang H; Meng L; Song H; Zhou Q; Qu C; Zhao P; Li Q; Zou C; Liu X; Zhang Z
Autophagy; 2021 Mar; 17(3):723-742. PubMed ID: 32186433
[TBL] [Abstract] [Full Text] [Related]
9. The Role of Rho GTPases in Motility and Invasion of Glioblastoma Cells.
Al-Koussa H; Atat OE; Jaafar L; Tashjian H; El-Sibai M
Anal Cell Pathol (Amst); 2020; 2020():9274016. PubMed ID: 32089990
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10. Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor.
Zepecki JP; Snyder KM; Moreno MM; Fajardo E; Fiser A; Ness J; Sarkar A; Toms SA; Tapinos N
Oncogene; 2019 Mar; 38(10):1734-1750. PubMed ID: 30353164
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11. Daam1 activates RhoA to regulate Wnt5a‑induced glioblastoma cell invasion.
Liu G; Yan T; Li X; Sun J; Zhang B; Wang H; Zhu Y
Oncol Rep; 2018 Feb; 39(2):465-472. PubMed ID: 29207169
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12. EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion.
Misek SA; Chen J; Schroeder L; Rattanasinchai C; Sample A; Sarkaria JN; Gallo KA
Mol Cancer Res; 2017 Aug; 15(8):1085-1095. PubMed ID: 28487380
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13. Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.
Roos A; Dhruv HD; Mathews IT; Inge LJ; Tuncali S; Hartman LK; Chow D; Millard N; Yin HH; Kloss J; Loftus JC; Winkles JA; Berens ME; Tran NL
Oncotarget; 2017 Feb; 8(7):12234-12246. PubMed ID: 28103571
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14. The Cytoskeletal Adapter Protein Spinophilin Regulates Invadopodia Dynamics and Tumor Cell Invasion in Glioblastoma.
Cheerathodi M; Avci NG; Guerrero PA; Tang LK; Popp J; Morales JE; Chen Z; Carnero A; Lang FF; Ballif BA; Rivera GM; McCarty JH
Mol Cancer Res; 2016 Dec; 14(12):1277-1287. PubMed ID: 27655131
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15. Rab23 is overexpressed in human astrocytoma and promotes cell migration and invasion through regulation of rac1.
Wang M; Dong Q; Wang Y
Tumour Biol; 2016 Aug; 37(8):11049-55. PubMed ID: 26897750
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16. Penfluridol: An Antipsychotic Agent Suppresses Metastatic Tumor Growth in Triple-Negative Breast cancer by Inhibiting Integrin Signaling Axis.
Ranjan A; Gupta P; Srivastava SK
Cancer Res; 2016 Feb; 76(4):877-90. PubMed ID: 26627008
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17. Glycogen synthase kinase 3β sustains invasion of glioblastoma via the focal adhesion kinase, rac1, and c-Jun N-terminal kinase-mediated pathway.
Chikano Y; Domoto T; Furuta T; Sabit H; Kitano-Tamura A; Pyko IV; Takino T; Sai Y; Hayashi Y; Sato H; Miyamoto K; Nakada M; Minamoto T
Mol Cancer Ther; 2015 Feb; 14(2):564-74. PubMed ID: 25504636
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18. Sema3C promotes the survival and tumorigenicity of glioma stem cells through rac1 activation.
Man J; Shoemake J; Zhou W; Fang X; Wu Q; Rizzo A; Prayson R; Bao S; Rich JN; Yu JS
Cell Rep; 2014 Dec; 9(5):1812-1826. PubMed ID: 25464848
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19. High incidence of naevi-associated BRAF wild-type melanoma and dysplastic naevi under treatment with the class I BRAF inhibitor vemurafenib.
Göppner D; Müller J; Krüger S; Franke I; Gollnick H; Quist SR
Acta Derm Venereol; 2014 Sep; 94(5):517-20. PubMed ID: 24531394
[TBL] [Abstract] [Full Text] [Related]
20. Combined inhibition of HER1/EGFR and rac1 results in a synergistic antiproliferative effect on established and primary cultured human glioblastoma cells.
Karpel-Massler G; Westhoff MA; Zhou S; Nonnenmacher L; Dwucet A; Kast RE; Bachem MG; Wirtz CR; Debatin KM; Halatsch ME
Mol Cancer Ther; 2013 Sep; 12(9):1783-95. PubMed ID: 23832120
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