Terms: = Brain cancer AND SETD2, ENSG00000181555, 29072
27 results:
1. Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma.
Lim-Fat MJ; Iorgulescu JB; Rahman R; Bhave V; Muzikansky A; Woodward E; Whorral S; Allen M; Touat M; Li X; Xy G; Patel J; Gerstner ER; Kalpathy-Cramer J; Youssef G; Chukwueke U; McFaline-Figueroa JR; Nayak L; Lee EQ; Reardon DA; Beroukhim R; Huang RY; Bi WL; Ligon KL; Wen PY
Clin Cancer Res; 2024 Apr; 30(7):1327-1337. PubMed ID: 38252427
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2. "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
Hadad S; Gupta R; Oberheim Bush NA; Taylor JW; Villanueva-Meyer JE; Young JS; Wu J; Ravindranathan A; Zhang Y; Warrier G; McCoy L; Shai A; Pekmezci M; Perry A; Bollen AW; Phillips JJ; Braunstein SE; Raleigh DR; Theodosopoulos P; Aghi MK; Chang EF; Hervey-Jumper SL; Costello JF; de Groot J; Butowski NA; Clarke JL; Chang SM; Berger MS; Molinaro AM; Solomon DA
Acta Neuropathol; 2023 Dec; 147(1):3. PubMed ID: 38079020
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3. Individualized combination therapies based on whole-exome sequencing displayed significant clinical benefits in a glioblastoma patient with secondary osteosarcoma: case report and genetic characterization.
Yi GZ; Zhu TC; Que TS; Li ZY; Huang GL
BMC Neurol; 2022 Oct; 22(1):390. PubMed ID: 36271359
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4. Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes.
Bai J; Shi J; Zhang Y; Li C; Xiong Y; Koka H; Wang D; Zhang T; Song L; Luo W; Zhu B; Hicks B; Hutchinson A; Kirk E; Troester MA; Li M; Shen Y; Ma T; Wang J; Liu X; Wang S; Gui S; McMaster ML; Chanock SJ; Parry DM; Goldstein AM; Yang XR
Clin Cancer Res; 2023 Jan; 29(1):261-270. PubMed ID: 36260525
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5. Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma.
Siddaway R; Canty L; Pajovic S; Milos S; Coyaud E; Sbergio SG; Vadivel Anguraj AK; Lubanszky E; Yun HY; Portante A; Carette S; Zhang C; Moran MF; Raught B; Campos EI; Hawkins C
Acta Neuropathol; 2022 Nov; 144(5):1027-1048. PubMed ID: 36070144
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6. setd2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis.
Leung W; Teater M; Durmaz C; Meydan C; Chivu AG; Chadburn A; Rice EJ; Muley A; Camarillo JM; Arivalagan J; Li Z; Flowers CR; Kelleher NL; Danko CG; Imielinski M; Dave SS; Armstrong SA; Mason CE; Melnick AM
Cancer Discov; 2022 Jul; 12(7):1782-1803. PubMed ID: 35443279
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7. setd2 Palmitoylation Mediated by ZDHHC16 in Epidermal Growth Factor Receptor-Mutated Glioblastoma Promotes Ionizing Radiation-Induced DNA Damage.
Fan X; Sun S; Yang H; Ma H; Zhao C; Niu W; Fan J; Fang Z; Chen X
Int J Radiat Oncol Biol Phys; 2022 Jul; 113(3):648-660. PubMed ID: 35192890
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8. Comprehensive Genomic Characterization of A Case of Granular Cell Tumor of the Posterior Pituitary Gland: A Case Report.
Hong CS; Elsamadicy AA; Fisayo A; Inzucchi SE; Gopal PP; Vining EM; Erson-Omay EZ; Bulent Omay S
Front Endocrinol (Lausanne); 2021; 12():762095. PubMed ID: 34925233
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9. Comparative Molecular Analysis of Primary Central Nervous System Lymphomas and Matched Vitreoretinal Lymphomas by Vitreous Liquid Biopsy.
Balikov DA; Hu K; Liu CJ; Betz BL; Chinnaiyan AM; Devisetty LV; Venneti S; Tomlins SA; Cani AK; Rao RC
Int J Mol Sci; 2021 Sep; 22(18):. PubMed ID: 34576156
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10. Pro-inflammatory and proliferative microglia drive progression of glioblastoma.
Liu H; Sun Y; Zhang Q; Jin W; Gordon RE; Zhang Y; Wang J; Sun C; Wang ZJ; Qi X; Zhang J; Huang B; Gui Q; Yuan H; Chen L; Ma X; Fang C; Liu YQ; Yu X; Feng S
Cell Rep; 2021 Sep; 36(11):109718. PubMed ID: 34525361
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11. Histone Mark Profiling in Pediatric Astrocytomas Reveals Prognostic Significance of H3K9 Trimethylation and Histone Methyltransferase SUV39H1.
Klonou A; Korkolopoulou P; Gargalionis AN; Kanakoglou DS; Katifelis H; Gazouli M; Chlamydas S; Mitsios A; Kalamatianos T; Stranjalis G; Themistocleous MS; Papavassiliou KA; Sgouros S; Papavassiliou AG; Piperi C
Neurotherapeutics; 2021 Jul; 18(3):2073-2090. PubMed ID: 34296393
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12. Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study.
Callens C; Driouch K; Boulai A; Tariq Z; Comte A; Berger F; Belin L; Bièche I; Servois V; Legoix P; Bernard V; Baulande S; Chemlali W; Bidard FC; Fourchotte V; Salomon AV; Brain E; Lidereau R; Bachelot T; Saghatchian M; Campone M; Giacchetti S; Zafrani BS; Cottu P
Genome Med; 2021 Mar; 13(1):44. PubMed ID: 33722295
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13. Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells.
Huang TY; Piunti A; Qi J; Morgan M; Bartom E; Shilatifard A; Saratsis AM
Acta Neuropathol Commun; 2020 Dec; 8(1):219. PubMed ID: 33287886
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14. Histone H3G34 Mutation in brain and Bone Tumors.
Qiu L; Han J
Adv Exp Med Biol; 2021; 1283():63-71. PubMed ID: 33155138
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15. Genotype-phenotype correlation at codon 1740 of setd2.
Rabin R; Radmanesh A; Glass IA; Dobyns WB; Aldinger KA; Shieh JT; Romoser S; Bombei H; Dowsett L; Trapane P; Bernat JA; Baker J; Mendelsohn NJ; Popp B; Siekmeyer M; Sorge I; Sansbury FH; Watts P; Foulds NC; Burton J; Hoganson G; Hurst JA; Menzies L; Osio D; Kerecuk L; Cobben JM; Jizi K; Jacquemont S; Bélanger SA; Löhner K; Veenstra-Knol HE; Lemmink HH; Keller-Ramey J; Wentzensen IM; Punj S; McWalter K; Lenberg J; Ellsworth KA; Radtke K; Akbarian S; Pappas J
Am J Med Genet A; 2020 Sep; 182(9):2037-2048. PubMed ID: 32710489
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16. Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma.
Liu SJ; Magill ST; Vasudevan HN; Hilz S; Villanueva-Meyer JE; Lastella S; Daggubati V; Spatz J; Choudhury A; Orr BA; Demaree B; Seo K; Ferris SP; Abate AR; Oberheim Bush NA; Bollen AW; McDermott MW; Costello JF; Raleigh DR
Cell Rep; 2020 Feb; 30(5):1300-1309.e5. PubMed ID: 32023450
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17. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Chang S; Yim S; Park H
Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
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18. Whole-exome sequencing revealed mutational profiles of giant cell glioblastomas.
Shi ZF; Li KK; Kwan JSH; Yang RR; Aibaidula A; Tang Q; Bao Y; Mao Y; Chen H; Ng HK
Brain Pathol; 2019 Nov; 29(6):782-792. PubMed ID: 30861589
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19. setd2 mutations in primary central nervous system tumors.
Viaene AN; Santi M; Rosenbaum J; Li MM; Surrey LF; Nasrallah MP
Acta Neuropathol Commun; 2018 Nov; 6(1):123. PubMed ID: 30419952
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20. Acquired setd2 mutation and impaired CREB1 activation confer cisplatin resistance in metastatic non-small cell lung cancer.
Kim IK; McCutcheon JN; Rao G; Liu SV; Pommier Y; Skrzypski M; Zhang YW; Giaccone G
Oncogene; 2019 Jan; 38(2):180-193. PubMed ID: 30093630
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