Terms: = Brain cancer AND SMO, Q99835, 6608, ENSG00000128602, SMOH, Gx AND Treatment
60 results:
1. Meningioma: current updates on genetics, classification, and mouse modeling.
Szulzewsky F; Thirimanne HN; Holland EC
Ups J Med Sci; 2024; 129():. PubMed ID: 38571886
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2. Harnessing the potential of nanoengineered siRNAs carriers for target responsive glioma therapy: Recent progress and future opportunities.
Ahirwar K; Kumar A; Srivastava N; Saraf SA; Shukla R
Int J Biol Macromol; 2024 May; 266(Pt 1):131048. PubMed ID: 38522697
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3. Plasma ctDNA Monitoring of a PTCH1-Mutant Metastatic Adult Medulloblastoma Showing a Durable Benefit With Vismodegib.
Cabezas-Camarero S; García-Barberán V; Pérez-Alfayate R; Gómez Del Pulgar ME; Cabrera-Martin MN; Casado-Fariñas I; Pérez-Segura P
Oncologist; 2024 May; 29(5):377-383. PubMed ID: 38438322
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4. Intraventricular SHH inhibition proves efficient in SHH medulloblastoma mouse model and prevents systemic side effects.
Kresbach C; Holst L; Schoof M; Leven T; Göbel C; Neyazi S; Tischendorf J; Loose C; Wrzeszcz A; Yorgan T; Rutkowski S; Schüller U
Neuro Oncol; 2024 Apr; 26(4):609-622. PubMed ID: 37767814
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5. Emerging Roles of Hedgehog Signaling in cancer Immunity.
Giammona A; Crivaro E; Stecca B
Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36674836
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6. ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449.
Sloan AE; Nock CJ; Ye X; Buerki R; Chang S; Lesser G; Norden A; Cloughesy T; Olson J; Kerstetter-Fogle A; Rich J; Fisher J; Desideri S; Takebe N; Timmer W; Grossman S; Prados M
J Neurooncol; 2023 Jan; 161(1):33-43. PubMed ID: 36581779
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7. DNA methylation profiling of meningiomas highlights clinically distinct molecular subgroups.
Singh J; Sharma R; Shukla N; Narwal P; Katiyar A; Mahajan S; Sahu S; Garg A; Sharma MC; Suri A; Sarkar C; Suri V
J Neurooncol; 2023 Jan; 161(2):339-356. PubMed ID: 36564673
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8. Noncanonical activation of GLI signaling in SOX2
Swiderska-Syn M; Mir-Pedrol J; Oles A; Schleuger O; Salvador AD; Greiner SM; Seward C; Yang F; Babcock BR; Shen C; Wynn DT; Sanchez-Mejias A; Gershon TR; Martin V; McCrea HJ; Lindsey KG; Krieg C; Rodriguez-Blanco J
Sci Adv; 2022 Jul; 8(29):eabj9138. PubMed ID: 35857834
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9. Curcumin analogue BDDD-721 exhibits more potent anticancer effects than curcumin on medulloblastoma by targeting Shh/Gli1 signaling pathway.
Gong W; Zhao W; Liu G; Shi L; Zhao X
Aging (Albany NY); 2022 Jul; 14(13):5464-5477. PubMed ID: 35802536
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10. Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in supratentorial ependymoma.
de Almeida Magalhães T; Alencastro Veiga Cruzeiro G; Ribeiro de Sousa G; Englinger B; Fernando Peinado Nagano L; Ancliffe M; Rodrigues da Silva K; Jiang L; Gojo J; Cherry Liu Y; Carline B; Kuchibhotla M; Pinto Saggioro F; Kazue Nagahashi Marie S; Mieko Oba-Shinjo S; Andres Yunes J; Gomes de Paula Queiroz R; Alberto Scrideli C; Endersby R; Filbin MG; Silva Borges K; Salic A; Gonzaga Tone L; Valera ET
Neuro Oncol; 2023 Jan; 25(1):185-198. PubMed ID: 35640920
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11. Targeting AKT and CK2 represents a novel therapeutic strategy for smo constitutive activation-driven medulloblastoma.
Yao YL; Wang YX; Yang FC; Wang C; Mao M; Gai QJ; He J; Qin Y; Yao XX; Lan X; Zhu J; Lu HM; Zeng H; Yao XH; Bian XW; Wang Y
CNS Neurosci Ther; 2022 Jul; 28(7):1033-1044. PubMed ID: 35419951
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12. [The Potential of Personalized/Precision Medicine for Meningiomas].
Yamaguchi S; Fujimura M
No Shinkei Geka; 2022 Jan; 50(1):132-140. PubMed ID: 35169093
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13. [Medulloblastoma].
Kanemura Y
No Shinkei Geka; 2022 Jan; 50(1):73-90. PubMed ID: 35169088
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14. smoothened is a therapeutic target for reducing glutamate toxicity in ischemic stroke.
Wang Y; Lu S; Chen Y; Li L; Li X; Qu Z; Huang J; Fan L; Yuan C; Song N; Zhang J; Xu W; Yang S; Wang Y
Sci Transl Med; 2021 Sep; 13(610):eaba3444. PubMed ID: 34516830
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15. STAT3 is required for smo-dependent signaling and mediates smo-targeted treatment resistance and tumorigenesis in Shh medulloblastoma.
Yuan L; Zhang H; Liu J; Malhotra A; Dey A; Yu B; Jella KK; McSwain LF; Schniederjan MJ; MacDonald TJ
Mol Oncol; 2022 Feb; 16(4):1009-1025. PubMed ID: 34482626
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16. G-protein-coupled receptors as therapeutic targets for glioblastoma.
Byrne KF; Pal A; Curtin JF; Stephens JC; Kinsella GK
Drug Discov Today; 2021 Dec; 26(12):2858-2870. PubMed ID: 34271165
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17. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma.
Wei SF; He DH; Zhang SB; Lu Y; Ye X; Fan XZ; Wang H; Wang Q; Liu YQ
Biochem Pharmacol; 2021 Aug; 190():114593. PubMed ID: 33964282
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18. Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.
Korshunov A; Okonechnikov K; Stichel D; Ryzhova M; Schrimpf D; Sahm F; Sievers P; Absalyamova O; Zheludkova O; Golanov A; Jones DTW; Pfister SM; von Deimling A; Kool M
Neuro Oncol; 2021 Sep; 23(9):1576-1585. PubMed ID: 33589929
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19. A novel protein encoded by circular smo RNA is essential for Hedgehog signaling activation and glioblastoma tumorigenicity.
Wu X; Xiao S; Zhang M; Yang L; Zhong J; Li B; Li F; Xia X; Li X; Zhou H; Liu D; Huang N; Yang X; Xiao F; Zhang N
Genome Biol; 2021 Jan; 22(1):33. PubMed ID: 33446260
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20. Clinical and mutational profiles of adult medulloblastoma groups.
Wong GC; Li KK; Wang WW; Liu AP; Huang QJ; Chan AK; Poon MF; Chung NY; Wong QH; Chen H; Chan DTM; Liu XZ; Mao Y; Zhang ZY; Shi ZF; Ng HK
Acta Neuropathol Commun; 2020 Nov; 8(1):191. PubMed ID: 33172502
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