Terms: = Brain cancer AND TFEB, TCFEB, 7942, ENSG00000112561, P19484, AlphaTFEB
20 results:
1. Hypoxia-induced galectin-8 maintains stemness in glioma stem cells via autophagy regulation.
Liu D; Zhu H; Cheng L; Li R; Ma X; Wang J; Wang J; Zhang S; Li Y; Shu K; Yu X; Li C
Neuro Oncol; 2024 May; 26(5):872-888. PubMed ID: 38158714
[TBL] [Abstract] [Full Text] [Related]
2. S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome.
Yang YH; Li W; Ren LW; Yang H; Zhang YZ; Zhang S; Hao Y; Yu DK; Tong RS; Du GH; Shi JY; Wang JH
Acta Pharmacol Sin; 2024 Jan; 45(1):209-222. PubMed ID: 37749236
[TBL] [Abstract] [Full Text] [Related]
3. Neratinib is a tfeb and TFE3 activator that potentiates autophagy and unbalances energy metabolism in ERBB2+ breast cancer cells.
Bellese G; Tagliatti E; Gagliani MC; Santamaria S; Arnaldi P; Falletta P; Rusmini P; Matteoli M; Castagnola P; Cortese K
Biochem Pharmacol; 2023 Jul; 213():115633. PubMed ID: 37269887
[TBL] [Abstract] [Full Text] [Related]
4. EWI2 and its relatives in Tetraspanin-enriched membrane domains regulate malignancy.
Ding Y; Chen J; Li S; Wren JD; Bajpai AK; Wang J; Tanaka T; Rice HC; Hays FA; Lu L; Zhang XA
Oncogene; 2023 Mar; 42(12):861-868. PubMed ID: 36788350
[TBL] [Abstract] [Full Text] [Related]
5. GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila.
Frappaolo A; Karimpour-Ghahnavieh A; Cesare G; Sechi S; Fraschini R; Vaccari T; Giansanti MG
Cell Death Dis; 2022 Nov; 13(11):1003. PubMed ID: 36435842
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6. PERK activation by SB202190 ameliorates amyloidogenesis via the tfeb-induced autophagy-lysosomal pathway.
Do M; Park J; Chen Y; Rah SY; Nghiem TT; Gong JH; Ju SA; Kim BS; Yu R; Park JW; Ryter SW; Surh YJ; Kim UH; Joe Y; Chung HT
Aging (Albany NY); 2022 Feb; 14(3):1233-1252. PubMed ID: 35166693
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7. Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent tfeb/TFE3 regulation.
van der Welle REN; Jobling R; Burns C; Sanza P; van der Beek JA; Fasano A; Chen L; Zwartkruis FJ; Zwakenberg S; Griffin EF; Ten Brink C; Veenendaal T; Liv N; van Ravenswaaij-Arts CMA; Lemmink HH; Pfundt R; Blaser S; Sepulveda C; Lozano AM; Yoon G; Santiago-Sim T; Asensio CS; Caldwell GA; Caldwell KA; Chitayat D; Klumperman J
EMBO Mol Med; 2021 May; 13(5):e13258. PubMed ID: 33851776
[TBL] [Abstract] [Full Text] [Related]
8. tfeb-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response.
Kim J; Kim SH; Kang H; Lee S; Park SY; Cho Y; Lim YM; Ahn JW; Kim YH; Chung S; Choi CS; Jang YJ; Park HS; Heo Y; Kim KH; Lee MS
Nat Metab; 2021 Mar; 3(3):410-427. PubMed ID: 33758420
[TBL] [Abstract] [Full Text] [Related]
9. A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.
Napolitano G; Di Malta C; Esposito A; de Araujo MEG; Pece S; Bertalot G; Matarese M; Benedetti V; Zampelli A; Stasyk T; Siciliano D; Venuta A; Cesana M; Vilardo C; Nusco E; Monfregola J; Calcagnì A; Di Fiore PP; Huber LA; Ballabio A
Nature; 2020 Sep; 585(7826):597-602. PubMed ID: 32612235
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10. Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis.
Shi Q; Pei F; Silverman GA; Pak SC; Perlmutter DH; Liu B; Bahar I
Int J Mol Sci; 2020 Apr; 21(8):. PubMed ID: 32325894
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11. Inhibition of tfeb oligomerization by co-treatment of melatonin with vorinostat promotes the therapeutic sensitivity in glioblastoma and glioma stem cells.
Sung GJ; Kim SH; Kwak S; Park SH; Song JH; Jung JH; Kim H; Choi KC
J Pineal Res; 2019 Apr; 66(3):e12556. PubMed ID: 30648757
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12. Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers.
Nàger M; Sallán MC; Visa A; Pushparaj C; Santacana M; Macià A; Yeramian A; Cantí C; Herreros J
Autophagy; 2018; 14(4):619-636. PubMed ID: 29313411
[TBL] [Abstract] [Full Text] [Related]
13. Sinomenine Hydrochloride Inhibits Human Glioblastoma Cell Growth through Reactive Oxygen Species Generation and Autophagy-Lysosome Pathway Activation: An In Vitro and In Vivo Study.
Jiang Y; Jiao Y; Wang Z; Li T; Liu Y; Li Y; Zhao X; Wang D
Int J Mol Sci; 2017 Sep; 18(9):. PubMed ID: 28891980
[TBL] [Abstract] [Full Text] [Related]
14. Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance.
Bingel C; Koeneke E; Ridinger J; Bittmann A; Sill M; Peterziel H; Wrobel JK; Rettig I; Milde T; Fernekorn U; Weise F; Schober A; Witt O; Oehme I
Cell Death Dis; 2017 Aug; 8(8):e3013. PubMed ID: 28837150
[TBL] [Abstract] [Full Text] [Related]
15. Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy.
Li X; Qian X; Lu Z
Autophagy; 2017 Oct; 13(10):1790-1791. PubMed ID: 28820290
[TBL] [Abstract] [Full Text] [Related]
16. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.
Li X; Yu W; Qian X; Xia Y; Zheng Y; Lee JH; Li W; Lyu J; Rao G; Zhang X; Qian CN; Rozen SG; Jiang T; Lu Z
Mol Cell; 2017 Jun; 66(5):684-697.e9. PubMed ID: 28552616
[TBL] [Abstract] [Full Text] [Related]
17. mTORC1-independent tfeb activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.
Palmieri M; Pal R; Nelvagal HR; Lotfi P; Stinnett GR; Seymour ML; Chaudhury A; Bajaj L; Bondar VV; Bremner L; Saleem U; Tse DY; Sanagasetti D; Wu SM; Neilson JR; Pereira FA; Pautler RG; Rodney GG; Cooper JD; Sardiello M
Nat Commun; 2017 Feb; 8():14338. PubMed ID: 28165011
[TBL] [Abstract] [Full Text] [Related]
18. Therapeutic potential of autophagy-enhancing agents in Parkinson's disease.
Moors TE; Hoozemans JJ; Ingrassia A; Beccari T; Parnetti L; Chartier-Harlin MC; van de Berg WD
Mol Neurodegener; 2017 Jan; 12(1):11. PubMed ID: 28122627
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19. Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders.
Ghosh A; Jana M; Modi K; Gonzalez FJ; Sims KB; Berry-Kravis E; Pahan K
J Biol Chem; 2015 Apr; 290(16):10309-24. PubMed ID: 25750174
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20. Autophagy and lysosomal related protein expression patterns in human glioblastoma.
Giatromanolaki A; Sivridis E; Mitrakas A; Kalamida D; Zois CE; Haider S; Piperidou C; Pappa A; Gatter KC; Harris AL; Koukourakis MI
Cancer Biol Ther; 2014; 15(11):1468-78. PubMed ID: 25482944
[TBL] [Abstract] [Full Text] [Related]
