BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND TFEB, TCFEB, 7942, ENSG00000112561, P19484, AlphaTFEB AND Treatment
8 results:

  • 1. Hypoxia-induced galectin-8 maintains stemness in glioma stem cells via autophagy regulation.
    Liu D; Zhu H; Cheng L; Li R; Ma X; Wang J; Wang J; Zhang S; Li Y; Shu K; Yu X; Li C
    Neuro Oncol; 2024 May; 26(5):872-888. PubMed ID: 38158714
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome.
    Yang YH; Li W; Ren LW; Yang H; Zhang YZ; Zhang S; Hao Y; Yu DK; Tong RS; Du GH; Shi JY; Wang JH
    Acta Pharmacol Sin; 2024 Jan; 45(1):209-222. PubMed ID: 37749236
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Neratinib is a tfeb and TFE3 activator that potentiates autophagy and unbalances energy metabolism in ERBB2+ breast cancer cells.
    Bellese G; Tagliatti E; Gagliani MC; Santamaria S; Arnaldi P; Falletta P; Rusmini P; Matteoli M; Castagnola P; Cortese K
    Biochem Pharmacol; 2023 Jul; 213():115633. PubMed ID: 37269887
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. tfeb-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response.
    Kim J; Kim SH; Kang H; Lee S; Park SY; Cho Y; Lim YM; Ahn JW; Kim YH; Chung S; Choi CS; Jang YJ; Park HS; Heo Y; Kim KH; Lee MS
    Nat Metab; 2021 Mar; 3(3):410-427. PubMed ID: 33758420
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Inhibition of tfeb oligomerization by co-treatment of melatonin with vorinostat promotes the therapeutic sensitivity in glioblastoma and glioma stem cells.
    Sung GJ; Kim SH; Kwak S; Park SH; Song JH; Jung JH; Kim H; Choi KC
    J Pineal Res; 2019 Apr; 66(3):e12556. PubMed ID: 30648757
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Sinomenine Hydrochloride Inhibits Human Glioblastoma Cell Growth through Reactive Oxygen Species Generation and Autophagy-Lysosome Pathway Activation: An In Vitro and In Vivo Study.
    Jiang Y; Jiao Y; Wang Z; Li T; Liu Y; Li Y; Zhao X; Wang D
    Int J Mol Sci; 2017 Sep; 18(9):. PubMed ID: 28891980
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance.
    Bingel C; Koeneke E; Ridinger J; Bittmann A; Sill M; Peterziel H; Wrobel JK; Rettig I; Milde T; Fernekorn U; Weise F; Schober A; Witt O; Oehme I
    Cell Death Dis; 2017 Aug; 8(8):e3013. PubMed ID: 28837150
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders.
    Ghosh A; Jana M; Modi K; Gonzalez FJ; Sims KB; Berry-Kravis E; Pahan K
    J Biol Chem; 2015 Apr; 290(16):10309-24. PubMed ID: 25750174
    [TBL] [Abstract] [Full Text] [Related]  


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