BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND TOP2A, TOP2, TP2A
35 results:

  • 1. The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma.
    Shirai Y; Ueno T; Kojima S; Ikeuchi H; Kitada R; Koyama T; Takahashi F; Takahashi K; Ichimura K; Yoshida A; Sugino H; Mano H; Narita Y; Takahashi M; Kohsaka S
    J Neurooncol; 2024 Mar; 167(1):75-88. PubMed ID: 38363490
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment.
    Ledvin L; Gassaway BM; Tawil J; Urso O; Pizzo D; Welsh KA; Bolhuis DL; Fisher D; Bonni A; Gygi SP; Brown NG; Ferguson CJ
    Dev Cell; 2023 Dec; 58(23):2666-2683.e9. PubMed ID: 37875116
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targeted sequencing of cancer-related genes reveals a recurrent top2a variant which affects DNA binding and coincides with global transcriptional changes in glioblastoma.
    Gielniewski B; Poleszak K; Roura AJ; Szadkowska P; Jacek K; Krol SK; Guzik R; Wiechecka P; Maleszewska M; Kaza B; Marchel A; Czernicki T; Koziarski A; Zielinski G; Styk A; Kawecki M; Szczylik C; Czepko R; Banach M; Kaspera W; Szopa W; Bujko M; Czapski B; Zabek M; Iżycka-Świeszewska E; Kloc W; Nauman P; Cieslewicz J; Grajkowska W; Morosini N; Noushmehr H; Wojtas B; Kaminska B
    Int J Cancer; 2023 Sep; 153(5):1003-1015. PubMed ID: 37338006
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. An
    Özbek M; Toy HI; Oktay Y; Karakülah G; Suner A; Pavlopoulou A
    PeerJ; 2023; 11():e15096. PubMed ID: 36945359
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The potential bioactive ingredients and hub genes of five TCM prescriptions against lung adenocarcinoma were explored based on bioinformatics.
    Liu T; Wei J
    Naunyn Schmiedebergs Arch Pharmacol; 2023 Sep; 396(9):2039-2055. PubMed ID: 36914901
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.
    Luo Z; Xin D; Liao Y; Berry K; Ogurek S; Zhang F; Zhang L; Zhao C; Rao R; Dong X; Li H; Yu J; Lin Y; Huang G; Xu L; Xin M; Nishinakamura R; Yu J; Kool M; Pfister SM; Roussel MF; Zhou W; Weiss WA; Andreassen P; Lu QR
    Nat Commun; 2023 Feb; 14(1):762. PubMed ID: 36765089
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Glioma Subtypes Based on the Activity Changes of Immunologic and Hallmark Gene Sets in cancer.
    Chen S
    Front Endocrinol (Lausanne); 2022; 13():879233. PubMed ID: 35774141
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Knockdown of NUSAP1 inhibits cell proliferation and invasion through downregulation of top2a in human glioblastoma.
    Hu Y; Xue Z; Qiu C; Feng Z; Qi Q; Wang J; Jin W; Zhong Z; Liu X; Li W; Zhang Q; Huang B; Chen A; Wang J; Yang N; Zhou W
    Cell Cycle; 2022 Sep; 21(17):1842-1855. PubMed ID: 35532155
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Comparative analysis of transcriptomic profile, histology, and IDH mutation for classification of gliomas.
    Tran PMH; Tran LKH; Nechtman J; Dos Santos B; Purohit S; Satter KB; Dun B; Kolhe R; Sharma S; Bollag R; She JX
    Sci Rep; 2020 Nov; 10(1):20651. PubMed ID: 33244057
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Multivariate analysis reveals differentially expressed genes among distinct subtypes of diffuse astrocytic gliomas: diagnostic implications.
    González-García N; Nieto-Librero AB; Vital AL; Tao HJ; González-Tablas M; Otero Á; Galindo-Villardón P; Orfao A; Tabernero MD
    Sci Rep; 2020 Jul; 10(1):11270. PubMed ID: 32647207
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Ribosomal protein S11 influences glioma response to top2 poisons.
    Awah CU; Chen L; Bansal M; Mahajan A; Winter J; Lad M; Warnke L; Gonzalez-Buendia E; Park C; Zhang D; Feldstein E; Yu D; Zannikou M; Balyasnikova IV; Martuscello R; Konerman S; Győrffy B; Burdett KB; Scholtens DM; Stupp R; Ahmed A; Hsu P; Sonabend AM
    Oncogene; 2020 Jul; 39(27):5068-5081. PubMed ID: 32528131
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Identification of Hub Genes in Atypical Teratoid/Rhabdoid Tumor by Bioinformatics Analyses.
    Pan X; Liu W; Chai Y; Hu L; Wang J; Zhang Y
    J Mol Neurosci; 2020 Nov; 70(11):1906-1913. PubMed ID: 32440821
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Network-Based Genetic Profiling Reveals Cellular Pathway Differences Between Follicular Thyroid Carcinoma and Follicular Thyroid Adenoma.
    Hossain MA; Asa TA; Rahman MM; Uddin S; Moustafa AA; Quinn JMW; Moni MA
    Int J Environ Res Public Health; 2020 Feb; 17(4):. PubMed ID: 32093341
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Proteomics and molecular network analyses reveal that the interaction between the TAT-DCF1 peptide and TAF6 induces an antitumor effect in glioma cells.
    Wang J; Wang F; Li Q; Wang Q; Li J; Wang Y; Sun J; Lu D; Zhou H; Li S; Ma S; Xie J; Wen T
    Mol Omics; 2020 Feb; 16(1):73-82. PubMed ID: 31899468
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Inhibition of DNA-PK potentiates the synergistic effect of NK314 and etoposide combination on human glioblastoma cells.
    Kopa P; Macieja A; Gulbas I; Pastwa E; Poplawski T
    Mol Biol Rep; 2020 Jan; 47(1):67-76. PubMed ID: 31583565
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The Inhibition of miR-144-3p on Cell Proliferation and Metastasis by Targeting top2a in HCMV-Positive Glioblastoma Cells.
    Song J; Ma Q; Hu M; Qian D; Wang B; He N
    Molecules; 2018 Dec; 23(12):. PubMed ID: 30544723
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. 3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
    Li W; Liu J; Fu W; Zheng X; Ren L; Liu S; Wang J; Ji T; Du G
    J Exp Clin Cancer Res; 2018 Jul; 37(1):132. PubMed ID: 29970196
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Profiles of brain metastases: Prioritization of therapeutic targets.
    Ferguson SD; Zheng S; Xiu J; Zhou S; Khasraw M; Brastianos PK; Kesari S; Hu J; Rudnick J; Salacz ME; Piccioni D; Huang S; Davies MA; Glitza IC; Heymach JV; Zhang J; Ibrahim NK; DeGroot JF; McCarty J; O'Brien BJ; Sawaya R; Verhaak RGW; Reddy SK; Priebe W; Gatalica Z; Spetzler D; Heimberger AB
    Int J Cancer; 2018 Dec; 143(11):3019-3026. PubMed ID: 29923182
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Rethinking medulloblastoma from a targeted therapeutics perspective.
    Hashimoto Y; Penas-Prado M; Zhou S; Wei J; Khatua S; Hodges TR; Sanai N; Xiu J; Gatalica Z; Kim L; Kesari S; Rao G; Spetzler D; Heimberger A
    J Neurooncol; 2018 Sep; 139(3):713-720. PubMed ID: 29869738
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma Cell Lines.
    Aaberg-Jessen C; Fogh L; Sørensen MD; Halle B; Brünner N; Kristensen BW
    Pathol Oncol Res; 2019 Jan; 25(1):59-69. PubMed ID: 28963609
    [TBL] [Abstract] [Full Text] [Related]  


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