BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Brain cancer AND TP53, TRP53, 7157, ENSG00000141510, P04637, LFS1, P53 AND Clinical Outcome
96 results:

  • 1. Relevance of mutations in protein deubiquitinases genes and
    Pękul M; Szczepaniak M; Kober P; Rusetska N; Mossakowska BJ; Baluszek S; Kowalik A; Maksymowicz M; Zieliński G; Kunicki J; Witek P; Bujko M
    Front Endocrinol (Lausanne); 2024; 15():1302667. PubMed ID: 38487343
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.
    Kolodziejczak AS; Guerrini-Rousseau L; Planchon JM; Ecker J; Selt F; Mynarek M; Obrecht D; Sill M; Autry RJ; Stutheit-Zhao E; Hirsch S; Amouyal E; Dufour C; Ayrault O; Torrejon J; Waszak SM; Ramaswamy V; Pentikainen V; Demir HA; Clifford SC; Schwalbe EC; Massimi L; Snuderl M; Galbraith K; Karajannis MA; Hill K; Li BK; Walsh M; White CL; Redmond S; Loizos L; Jakob M; Kordes UR; Schmid I; Hauer J; Blattmann C; Filippidou M; Piccolo G; Scheurlen W; Farrag A; Grund K; Sutter C; Pietsch T; Frank S; Schewe DM; Malkin D; Ben-Arush M; Sehested A; Wong TT; Wu KS; Liu YL; Carceller F; Mueller S; Stoller S; Taylor MD; Tabori U; Bouffet E; Kool M; Sahm F; von Deimling A; Korshunov A; von Hoff K; Kratz CP; Sturm D; Jones DTW; Rutkowski S; van Tilburg CM; Witt O; Bougeard G; Pajtler KW; Pfister SM; Bourdeaut F; Milde T
    Neuro Oncol; 2023 Dec; 25(12):2273-2286. PubMed ID: 37379234
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Cystic versus non-cystic silent corticotrophic adenomas: clinical and histological analysis of 62 cases after microscopic transsphenoidal surgery-a retrospective, single-center study.
    Sumislawski P; Huckhagel T; Krajewski KL; Aberle J; Saeger W; Flitsch J; Rotermund R
    Sci Rep; 2023 Feb; 13(1):2468. PubMed ID: 36774403
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker outcomes from PNOC003.
    Kline C; Jain P; Kilburn L; Bonner ER; Gupta N; Crawford JR; Banerjee A; Packer RJ; Villanueva-Meyer J; Luks T; Zhang Y; Kambhampati M; Zhang J; Yadavilli S; Zhang B; Gaonkar KS; Rokita JL; Kraya A; Kuhn J; Liang W; Byron S; Berens M; Molinaro A; Prados M; Resnick A; Waszak SM; Nazarian J; Mueller S
    Clin Cancer Res; 2022 Sep; 28(18):3965-3978. PubMed ID: 35852795
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Can a signature molecular-profile define disparate survival in BRAF-positive Gliosarcoma and identify novel targets for therapeutic intervention?
    Gandhi P; Khare R; Garg N; Mishra J
    J Cancer Res Ther; 2022; 18(1):224-230. PubMed ID: 35381788
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent tp53 mutations and recurrent monosomy 13.
    Pratt D; Abdullaev Z; Papanicolau-Sengos A; Ketchum C; Panneer Selvam P; Chung HJ; Lee I; Raffeld M; Gilbert MR; Armstrong TS; Pytel P; Borys E; Klonoski JM; McCord M; Horbinski C; Brat D; Perry A; Solomon D; Eberhart C; Giannini C; Quezado M; Aldape K
    Acta Neuropathol; 2022 Mar; 143(3):403-414. PubMed ID: 35103816
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. A concise review on the role of BDNF-AS in human disorders.
    Ghafouri-Fard S; Khoshbakht T; Taheri M; Ghanbari M
    Biomed Pharmacother; 2021 Oct; 142():112051. PubMed ID: 34426254
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
    Suwala AK; Stichel D; Schrimpf D; Kloor M; Wefers AK; Reinhardt A; Maas SLN; Kratz CP; Schweizer L; Hasselblatt M; Snuderl M; Abedalthagafi MSJ; Abdullaev Z; Monoranu CM; Bergmann M; Pekrun A; Freyschlag C; Aronica E; Kramm CM; Hinz F; Sievers P; Korshunov A; Kool M; Pfister SM; Sturm D; Jones DTW; Wick W; Unterberg A; Hartmann C; Dodgshun A; Tabori U; Wesseling P; Sahm F; von Deimling A; Reuss DE
    Acta Neuropathol; 2021 Jan; 141(1):85-100. PubMed ID: 33216206
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Steroid receptor-associated and regulated protein is a biomarker in predicting the clinical outcome and treatment response in malignancies.
    Naderi A
    Cancer Rep (Hoboken); 2020 Oct; 3(5):e1267. PubMed ID: 32706923
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Primary central nervous system lymphomas associated with chronic inflammation: diagnostic pitfalls of central nervous system lymphomas.
    Sugita Y; Masuoka J; Kameda K; Takahashi K; Kimura Y; Higaki K; Furuta T; Ohshima K
    Brain Tumor Pathol; 2020 Oct; 37(4):127-135. PubMed ID: 32627089
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Expression of GNAS, tp53, and PTEN Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup.
    da Silva LS; Mançano BM; de Paula FE; Dos Reis MB; de Almeida GC; Matsushita M; Junior CA; Evangelista AF; Saggioro F; Serafini LN; Stavale JN; Malheiros SMF; Lima M; Hajj GNM; de Lima MA; Taylor MD; Leal LF; Reis RM
    J Mol Diagn; 2020 Jul; 22(7):957-966. PubMed ID: 32380172
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. DNA methylation signature is prognostic of choroid plexus tumor aggressiveness.
    Pienkowska M; Choufani S; Turinsky AL; Guha T; Merino DM; Novokmet A; Brudno M; Weksberg R; Shlien A; Hawkins C; Bouffet E; Tabori U; Gilbertson RJ; Finlay JL; Jabado N; Thomas C; Sill M; Capper D; Hasselblatt M; Malkin D
    Clin Epigenetics; 2019 Aug; 11(1):117. PubMed ID: 31409384
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. A germline variant of tp53 in paediatric diffuse leptomeningeal glioneuronal tumour.
    Tan GIL; Merchant K; Tan EEK; Low DCY; Ng LP; Seow WT; Low SYY
    Childs Nerv Syst; 2019 Jun; 35(6):1021-1027. PubMed ID: 30937530
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Modulation of Mutant
    Zhou X; Padanad MS; Evers BM; Smith B; Novaresi N; Suresh S; Richardson JA; Stein E; Zhu J; Hammer RE; O'Donnell KA
    Mol Cancer Res; 2019 Feb; 17(2):594-603. PubMed ID: 30409919
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Usefulness of complementary next-generation sequencing and quantitative immunohistochemistry panels for predicting brain metastases and selecting treatment outcomes of non-small cell lung cancer.
    Machado-Rugolo J; Fabro AT; Ascheri D; Farhat C; Ab'Saber AM; de Sá VK; Nagai MA; Takagaki T; Terra R; Parra ER; Capelozzi VL
    Hum Pathol; 2019 Jan; 83():177-191. PubMed ID: 30218756
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Medulloblastoma, WNT-activated/SHH-activated: clinical impact of molecular analysis and histogenetic evaluation.
    Cambruzzi E
    Childs Nerv Syst; 2018 May; 34(5):809-815. PubMed ID: 29582169
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Tracking the Evolution of Non-Small-Cell Lung cancer.
    Jamal-Hanjani M; Wilson GA; McGranahan N; Birkbak NJ; Watkins TBK; Veeriah S; Shafi S; Johnson DH; Mitter R; Rosenthal R; Salm M; Horswell S; Escudero M; Matthews N; Rowan A; Chambers T; Moore DA; Turajlic S; Xu H; Lee SM; Forster MD; Ahmad T; Hiley CT; Abbosh C; Falzon M; Borg E; Marafioti T; Lawrence D; Hayward M; Kolvekar S; Panagiotopoulos N; Janes SM; Thakrar R; Ahmed A; Blackhall F; Summers Y; Shah R; Joseph L; Quinn AM; Crosbie PA; Naidu B; Middleton G; Langman G; Trotter S; Nicolson M; Remmen H; Kerr K; Chetty M; Gomersall L; Fennell DA; Nakas A; Rathinam S; Anand G; Khan S; Russell P; Ezhil V; Ismail B; Irvin-Sellers M; Prakash V; Lester JF; Kornaszewska M; Attanoos R; Adams H; Davies H; Dentro S; Taniere P; O'Sullivan B; Lowe HL; Hartley JA; Iles N; Bell H; Ngai Y; Shaw JA; Herrero J; Szallasi Z; Schwarz RF; Stewart A; Quezada SA; Le Quesne J; Van Loo P; Dive C; Hackshaw A; Swanton C;
    N Engl J Med; 2017 Jun; 376(22):2109-2121. PubMed ID: 28445112
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. HDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cells.
    Marampon F; Megiorni F; Camero S; Crescioli C; McDowell HP; Sferra R; Vetuschi A; Pompili S; Ventura L; De Felice F; Tombolini V; Dominici C; Maggio R; Festuccia C; Gravina GL
    Cancer Lett; 2017 Jul; 397():1-11. PubMed ID: 28342984
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT.
    Hill R; Madureira PA; Ferreira B; Baptista I; Machado S; Colaço L; Dos Santos M; Liu N; Dopazo A; Ugurel S; Adrienn A; Kiss-Toth E; Isbilen M; Gure AO; Link W
    Nat Commun; 2017 Mar; 8():14687. PubMed ID: 28276427
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional PI3K inhibition.
    Craveiro RB; Ehrhardt M; Velz J; Olschewski M; Goetz B; Pietsch T; Dilloo D
    Oncotarget; 2017 Jul; 8(29):46915-46927. PubMed ID: 28159923
    [TBL] [Abstract] [Full Text] [Related]  


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