BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Breast cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Clinical Outcome
78 results:

  • 1. Two-Dimensional-PAGE Coupled with nLC-MS/MS-Based Identification of Differentially Expressed Proteins and Tumorigenic Pathways in MCF7 breast cancer Cells Transfected for JTB Protein Silencing.
    Jayathirtha M; Jayaweera T; Whitham D; Sullivan I; Petre BA; Darie CC; Neagu AN
    Molecules; 2023 Nov; 28(22):. PubMed ID: 38005222
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer.
    Wang X; Yu J; Liu X; Luo D; Li Y; Song L; Jiang X; Yin X; Wang Y; Chai L; Luo T; Jing J; Shi H
    Cell Rep Med; 2022 Sep; 3(9):100741. PubMed ID: 36099919
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. TRAF4 hyperactivates HER2 signaling and contributes to Trastuzumab resistance in HER2-positive breast cancer.
    Gu Y; Gao H; Zhang H; John A; Zhu X; Shivaram S; Yu J; Weinshilboum RM; Wang L
    Oncogene; 2022 Aug; 41(35):4119-4129. PubMed ID: 35864174
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Withaferin A mediated changes of miRNA expression in breast cancer-derived mammospheres.
    Prajapati KS; Shuaib M; Gupta S; Kumar S
    Mol Carcinog; 2022 Sep; 61(9):876-889. PubMed ID: 35770722
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Co-targeting CDK4/6 and akt with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer.
    Alves CL; Ehmsen S; Terp MG; Portman N; Tuttolomondo M; Gammelgaard OL; Hundebøl MF; Kaminska K; Johansen LE; Bak M; Honeth G; Bosch A; Lim E; Ditzel HJ
    Nat Commun; 2021 Aug; 12(1):5112. PubMed ID: 34433817
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Biological and clinical features of triple negative Invasive Lobular Carcinomas of the breast. clinical outcome and actionable molecular alterations.
    Conforti F; Pala L; Pagan E; Rocco EG; Bagnardi V; Montagna E; Peruzzotti G; De Pas T; Fumagalli C; Pileggi S; Pesenti C; Marchini S; Corso G; Marchio' C; Sapino A; Graffeo R; Collet L; Aftimos P; Sotiriou C; Piccart M; Gelber RD; Viale G; Colleoni M; Goldhirsch A
    Breast; 2021 Oct; 59():94-101. PubMed ID: 34217971
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. S100A4 Is Involved in Stimulatory Effects Elicited by the FGF2/FGFR1 Signaling Pathway in Triple-Negative breast cancer (TNBC) Cells.
    Santolla MF; Talia M; Maggiolini M
    Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946884
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. SENP3 loss promotes M2 macrophage polarization and breast cancer progression.
    Xiao M; Bian Q; Lao Y; Yi J; Sun X; Sun X; Yang J
    Mol Oncol; 2022 Feb; 16(4):1026-1044. PubMed ID: 33932085
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Transmembrane and coiled-coil domain family 3 (TMCC3) regulates breast cancer stem cell and akt activation.
    Wang YH; Chan YT; Hung TH; Hung JT; Kuo MW; Wang SH; Huang Y; Lin YJ; Chen SC; Yu JC; Wu JC; Yu J; Yu AL
    Oncogene; 2021 Apr; 40(16):2858-2871. PubMed ID: 33742122
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Mutant TP53 interacts with BCAR1 to contribute to cancer cell invasion.
    Guo AK; Itahana Y; Seshachalam VP; Chow HY; Ghosh S; Itahana K
    Br J Cancer; 2021 Jan; 124(1):299-312. PubMed ID: 33144694
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance.
    Li L; Lin L; Veeraraghavan J; Hu Y; Wang X; Lee S; Tan Y; Schiff R; Wang XS
    Breast Cancer Res; 2020 Aug; 22(1):84. PubMed ID: 32771039
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Clinicopathological Evaluation of the Potential Anatomic Pathways of Systemic Metastasis from Primary breast cancer Suggests an Orderly Spread Through the Regional Lymph Nodes.
    David Nathanson S; Leonard-Murali S; Burmeister C; Susick L; Baker P
    Ann Surg Oncol; 2020 Nov; 27(12):4810-4818. PubMed ID: 32720039
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. A nuclear lncRNA Linc00839 as a Myc target to promote breast cancer chemoresistance via PI3K/akt signaling pathway.
    Chen Q; Shen H; Zhu X; Liu Y; Yang H; Chen H; Xiong S; Chi H; Xu W
    Cancer Sci; 2020 Sep; 111(9):3279-3291. PubMed ID: 32619088
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Molecular stratification within triple-negative breast cancer subtypes.
    Wang DY; Jiang Z; Ben-David Y; Woodgett JR; Zacksenhaus E
    Sci Rep; 2019 Dec; 9(1):19107. PubMed ID: 31836816
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways.
    Nan X; Wang J; Cheng H; Yin Z; Sheng J; Qiu B; Lau CC; Yustein JT; Zhao H; Wong STC
    Cancer Lett; 2020 Jan; 469():195-206. PubMed ID: 31672491
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Role of miRNA-Regulated cancer Stem Cells in the Pathogenesis of Human Malignancies.
    Khan AQ; Ahmed EI; Elareer NR; Junejo K; Steinhoff M; Uddin S
    Cells; 2019 Aug; 8(8):. PubMed ID: 31530793
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. GATA1 promotes colorectal cancer cell proliferation, migration and invasion via activating akt signaling pathway.
    Yu J; Liu M; Liu H; Zhou L
    Mol Cell Biochem; 2019 Jul; 457(1-2):191-199. PubMed ID: 31069596
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The effects of PTPN2 loss on cell signalling and clinical outcome in relation to breast cancer subtype.
    Veenstra C; Karlsson E; Mirwani SM; Nordenskjöld B; Fornander T; Pérez-Tenorio G; Stål O
    J Cancer Res Clin Oncol; 2019 Jul; 145(7):1845-1856. PubMed ID: 31025094
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Improving surgical efficiency of immediate implant-based breast reconstruction following mastectomy.
    Nealon K; Rebello M; Sobti N; Sherburne A; Spracklin D; Liao EC; Specht M
    Breast Cancer Res Treat; 2019 Jul; 176(1):159-164. PubMed ID: 30977025
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Dissecting the predictive value of MAPK/akt/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES.
    Szijgyarto Z; Flach KD; Opdam M; Palmieri C; Linn SC; Wesseling J; Ali S; Bliss JM; Cheang MCU; Zwart W; Coombes RC
    Breast Cancer Res Treat; 2019 May; 175(1):149-163. PubMed ID: 30680659
    [TBL] [Abstract] [Full Text] [Related]  


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