BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Breast cancer AND KDM5A, RBBP2, 5927, JARID1A, ENSG00000073614
22 results:

  • 1. Comprehensive profiling of pathogenic germline large genomic rearrangements in a pan-cancer analysis.
    Sun Z; Bai C; Su M; Tang H; Wu X; Wang Y; Bao H; Liu X; Wu X; Shao Y; Xu B
    Mol Oncol; 2023 Sep; 17(9):1917-1929. PubMed ID: 37013911
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Targeting MLL Methyltransferases Enhances the Antitumor Effects of PI3K Inhibition in Hormone Receptor-positive breast cancer.
    Jones RB; Farhi J; Adams M; Parwani KK; Cooper GW; Zecevic M; Lee RS; Hong AL; Spangle JM
    Cancer Res Commun; 2022 Dec; 2(12):1569-1578. PubMed ID: 36970726
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Fbxo22 inhibits metastasis in triple-negative breast cancer through ubiquitin modification of kdm5a and regulation of H3K4me3 demethylation.
    Li S; He J; Liao X; He Y; Chen R; Chen J; Hu S; Sun J
    Cell Biol Toxicol; 2023 Aug; 39(4):1641-1655. PubMed ID: 36112263
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Expression and prognostic values of ARID family members in breast cancer.
    Zhang J; Hou S; You Z; Li G; Xu S; Li X; Zhang X; Lei B; Pang D
    Aging (Albany NY); 2021 Feb; 13(4):5621-5637. PubMed ID: 33592583
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Extended Recognition of the Histone H3 Tail by Histone Demethylase kdm5a.
    Petronikolou N; Longbotham JE; Fujimori DG
    Biochemistry; 2020 Feb; 59(5):647-651. PubMed ID: 31985200
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
    Chang S; Yim S; Park H
    Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases.
    Paroni G; Bolis M; Zanetti A; Ubezio P; Helin K; Staller P; Gerlach LO; Fratelli M; Neve RM; Terao M; Garattini E
    Oncogene; 2019 Apr; 38(15):2675-2689. PubMed ID: 30538297
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
    Hinohara K; Wu HJ; Vigneau S; McDonald TO; Igarashi KJ; Yamamoto KN; Madsen T; Fassl A; Egri SB; Papanastasiou M; Ding L; Peluffo G; Cohen O; Kales SC; Lal-Nag M; Rai G; Maloney DJ; Jadhav A; Simeonov A; Wagle N; Brown M; Meissner A; Sicinski P; Jaffe JD; Jeselsohn R; Gimelbrant AA; Michor F; Polyak K
    Cancer Cell; 2018 Dec; 34(6):939-953.e9. PubMed ID: 30472020
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genome-Wide Methylation Analysis Identifies NOX4 and kdm5a as Key Regulators in Inhibiting breast cancer Cell Proliferation by Ginsenoside Rg3.
    Ham J; Lee S; Lee H; Jeong D; Park S; Kim SJ
    Am J Chin Med; 2018; 46(6):1333-1355. PubMed ID: 30149757
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. ChIP-seq analysis reveals alteration of H3K4 trimethylation occupancy in cancer-related genes by cold atmospheric plasma.
    Lee S; Park S; Lee H; Jeong D; Ham J; Choi EH; Kim SJ
    Free Radic Biol Med; 2018 Oct; 126():133-141. PubMed ID: 30096431
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Selective Inhibition of Lysine-Specific Demethylase 5A (kdm5a) Using a Rhodium(III) Complex for Triple-Negative breast cancer Therapy.
    Yang GJ; Wang W; Mok SWF; Wu C; Law BYK; Miao XM; Wu KJ; Zhong HJ; Wong CY; Wong VKW; Ma DL; Leung CH
    Angew Chem Int Ed Engl; 2018 Oct; 57(40):13091-13095. PubMed ID: 29968419
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Structure-based design and discovery of potent and selective KDM5 inhibitors.
    Nie Z; Shi L; Lai C; O'Connell SM; Xu J; Stansfield RK; Hosfield DJ; Veal JM; Stafford JA
    Bioorg Med Chem Lett; 2018 May; 28(9):1490-1494. PubMed ID: 29627262
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Probing the metabolic phenotype of breast cancer cells by multiple tracer stable isotope resolved metabolomics.
    Lane AN; Tan J; Wang Y; Yan J; Higashi RM; Fan TW
    Metab Eng; 2017 Sep; 43(Pt B):125-136. PubMed ID: 28163219
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. KDM5 lysine demethylases are involved in maintenance of 3'UTR length.
    Blair LP; Liu Z; Labitigan RL; Wu L; Zheng D; Xia Z; Pearson EL; Nazeer FI; Cao J; Lang SM; Rines RJ; Mackintosh SG; Moore CL; Li W; Tian B; Tackett AJ; Yan Q
    Sci Adv; 2016 Nov; 2(11):e1501662. PubMed ID: 28138513
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.
    Gale M; Sayegh J; Cao J; Norcia M; Gareiss P; Hoyer D; Merkel JS; Yan Q
    Oncotarget; 2016 Jun; 7(26):39931-39944. PubMed ID: 27224921
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. PI3K/AKT Signaling Regulates H3K4 Methylation in breast cancer.
    Spangle JM; Dreijerink KM; Groner AC; Cheng H; Ohlson CE; Reyes J; Lin CY; Bradner J; Zhao JJ; Roberts TM; Brown M
    Cell Rep; 2016 Jun; 15(12):2692-704. PubMed ID: 27292631
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.
    Varier RA; Carrillo de Santa Pau E; van der Groep P; Lindeboom RG; Matarese F; Mensinga A; Smits AH; Edupuganti RR; Baltissen MP; Jansen PW; Ter Hoeve N; van Weely DR; Poser I; van Diest PJ; Stunnenberg HG; Vermeulen M
    J Biol Chem; 2016 Apr; 291(14):7313-24. PubMed ID: 26841866
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.
    Horton JR; Engstrom A; Zoeller EL; Liu X; Shanks JR; Zhang X; Johns MA; Vertino PM; Fu H; Cheng X
    J Biol Chem; 2016 Feb; 291(6):2631-46. PubMed ID: 26645689
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.
    Katoh M
    Expert Rev Proteomics; 2015 Jun; 12(3):317-28. PubMed ID: 25835095
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Histone lysine demethylases in breast cancer.
    Paolicchi E; Crea F; Farrar WL; Green JE; Danesi R
    Crit Rev Oncol Hematol; 2013 May; 86(2):97-103. PubMed ID: 23266085
    [TBL] [Abstract] [Full Text] [Related]  


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