Terms: = Breast cancer AND PIM1, PIM, 5292, ENSG00000137193, P11309 AND Treatment
27 results:
1. pim kinase inhibitor AZD1208 in conjunction with Th1 cytokines potentiate death of breast cancer cellsin vitrowhile also maximizing suppression of tumor growthin vivo when combined with immunotherapy.
Anwar A; Lepore C; Czerniecki BJ; Koski GK; Showalter LE
Cell Immunol; 2024; 397-398():104805. PubMed ID: 38244265
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2. Epigenomic Profiling Advises Therapeutic Potential of Leukotriene Receptor Inhibitors for a Subset of Triple-Negative breast Tumors.
Kalinkin AI; Sigin VO; Kuznetsova EB; Ignatova EO; Vinogradov II; Vinogradov MI; Vinogradov IY; Zaletaev DV; Nemtsova MV; Kutsev SI; Tanas AS; Strelnikov VV
Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139172
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3. Tailored horseshoe-shaped nicotinonitrile scaffold as dual promising c-Met and pim-1 inhibitors: Design, synthesis, SAR and in silico study.
Mohamady S; Khalil AF; Naguib BH; Nafie MS; Tawfik HO; Shaldam MA
Bioorg Chem; 2024 Feb; 143():106988. PubMed ID: 37995644
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4. Targeting pim2 by JP11646 results in significant antitumor effects in solid tumors.
Katsuta E; Gil-Moore M; Moore J; Yousif M; Adjei AA; Ding Y; Caserta J; Baldino CM; Lee KP; Gelman IH; Takabe K; Opyrchal M
Int J Oncol; 2022 Oct; 61(4):. PubMed ID: 35920189
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5. The Second-Generation pim Kinase Inhibitor TP-3654 Resensitizes ABCG2-Overexpressing Multidrug-Resistant cancer Cells to Cytotoxic Anticancer Drugs.
Wu CP; Li YQ; Chi YC; Huang YH; Hung TH; Wu YS
Int J Mol Sci; 2021 Aug; 22(17):. PubMed ID: 34502348
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6. Coexistence of two quadruplex-duplex hybrids in the pim1 gene.
Tan DJY; Winnerdy FR; Lim KW; Phan AT
Nucleic Acids Res; 2020 Nov; 48(19):11162-11171. PubMed ID: 32976598
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7. Preclinical evaluation of a novel triple-acting pim/PI3K/mTOR inhibitor, IBL-302, in breast cancer.
Kennedy SP; O'Neill M; Cunningham D; Morris PG; Toomey S; Blanco-Aparicio C; Martinez S; Pastor J; Eustace AJ; Hennessy BT
Oncogene; 2020 Apr; 39(14):3028-3040. PubMed ID: 32042115
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8. Prevalence and factors associated with potentially inappropriate medication use in older medicare beneficiaries with cancer.
Feng X; Higa GM; Safarudin F; Sambamoorthi U; Chang J
Res Social Adm Pharm; 2020 Oct; 16(10):1459-1471. PubMed ID: 31926877
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9. PCR Amplifiable DNA from breast Disease FFPE Section for Mutational Analysis.
Panchal NK; Bhale A; Chowdary R; Verma VK; Beevi SS
J Biomol Tech; 2020 Apr; 31(1):1-6. PubMed ID: 31695579
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10. Targeting PML in triple negative breast cancer elicits growth suppression and senescence.
Arreal L; Piva M; Fernández S; Revandkar A; Schaub-Clerigué A; Villanueva J; Zabala-Letona A; Pujana M; Astobiza I; Cortazar AR; Hermanova I; Bozal-Basterra L; Arruabarrena-Aristorena A; Crespo JR; Valcarcel-Jimenez L; Zúñiga-García P; Canals F; Torrano V; Barrio R; Sutherland JD; Alimonti A; Martin-Martin N; Carracedo A
Cell Death Differ; 2020 Apr; 27(4):1186-1199. PubMed ID: 31570853
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11. Targeting on glycosylation of mutant FLT3 in acute myeloid leukemia.
Hu X; Chen F
Hematology; 2019 Dec; 24(1):651-660. PubMed ID: 31533545
[No Abstract] [Full Text] [Related]
12. In Vitro and In Vivo Anti-breast cancer Activities of Some Newly Synthesized 5-(thiophen-2-yl)thieno-[2,3-d]pyrimidin-4-one Candidates.
Amr AEE; Ibrahimd AA; El-Shehry MF; Hosni HM; Fayed AA; Elsayed EA
Molecules; 2019 Jun; 24(12):. PubMed ID: 31212962
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13. pim1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation.
Gao X; Liu X; Lu Y; Wang Y; Cao W; Liu X; Hu H; Wang H
Breast Cancer; 2019 Sep; 26(5):663-671. PubMed ID: 30989585
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14. Potentially inappropriate medication use and associated healthcare utilization and costs among older adults with colorectal, breast, and prostate cancers.
Feng X; Higa GM; Safarudin F; Sambamoorthi U; Tan X
J Geriatr Oncol; 2019 Sep; 10(5):698-704. PubMed ID: 30772191
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15. Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers.
Cortes J; Tamura K; DeAngelo DJ; de Bono J; Lorente D; Minden M; Uy GL; Kantarjian H; Chen LS; Gandhi V; Godin R; Keating K; McEachern K; Vishwanathan K; Pease JE; Dean E
Br J Cancer; 2018 May; 118(11):1425-1433. PubMed ID: 29765150
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16. Post-irradiation morphoea of the breast: a case report and review of the literature.
Gonzalez-Ericsson PI; Estrada MV; Al-Rohil R; Sanders ME
Histopathology; 2018 Jan; 72(2):342-350. PubMed ID: 29110314
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17. Potential Medication-Related Problems in Older breast, Colon, and Lung cancer Patients in the United States.
Lund JL; Sanoff HK; Peacock Hinton S; Muss HB; Pate V; Stürmer T
Cancer Epidemiol Biomarkers Prev; 2018 Jan; 27(1):41-49. PubMed ID: 28978563
[No Abstract] [Full Text] [Related]
18. pim1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
Brasó-Maristany F; Filosto S; Catchpole S; Marlow R; Quist J; Francesch-Domenech E; Plumb DA; Zakka L; Gazinska P; Liccardi G; Meier P; Gris-Oliver A; Cheang MC; Perdrix-Rosell A; Shafat M; Noël E; Patel N; McEachern K; Scaltriti M; Castel P; Noor F; Buus R; Mathew S; Watkins J; Serra V; Marra P; Grigoriadis A; Tutt AN
Nat Med; 2016 Nov; 22(11):1303-1313. PubMed ID: 27775704
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19. Systematic Functional Characterization of Resistance to PI3K Inhibition in breast cancer.
Le X; Antony R; Razavi P; Treacy DJ; Luo F; Ghandi M; Castel P; Scaltriti M; Baselga J; Garraway LA
Cancer Discov; 2016 Oct; 6(10):1134-1147. PubMed ID: 27604488
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20. MicroRNA-486-5p targeting pim-1 suppresses cell proliferation in breast cancer cells.
Zhang G; Liu Z; Cui G; Wang X; Yang Z
Tumour Biol; 2014 Nov; 35(11):11137-45. PubMed ID: 25104088
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