BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Breast cancer AND SMAD4, JIP, Q13485, 4089, ENSG00000141646, MADH4, DPC4 AND Treatment
59 results:

  • 1. An NFATc1/SMAD3/cJUN Complex Restricted to smad4-Deficient Pancreatic cancer Guides Rational Therapies.
    Hasselluhn MC; Schlösser D; Versemann L; Schmidt GE; Ulisse M; Oschwald J; Zhang Z; Hamdan F; Xiao H; Kopp W; Spitalieri J; Kellner C; Schneider C; Reutlinger K; Nagarajan S; Steuber B; Sastra SA; Palermo CF; Appelhans J; Bohnenberger H; Todorovic J; Kostyuchek I; Ströbel P; Bockelmann A; König A; Ammer-Herrmenau C; Schmidleitner L; Kaulfuß S; Wollnik B; Hahn SA; Neesse A; Singh SK; Bastians H; Reichert M; Sax U; Olive KP; Johnsen SA; Schneider G; Ellenrieder V; Hessmann E
    Gastroenterology; 2024 Feb; 166(2):298-312.e14. PubMed ID: 37913894
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. 5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-smad4 signaling.
    Singh DK; Carcamo S; Farias EF; Hasson D; Zheng W; Sun D; Huang X; Cheung J; Nobre AR; Kale N; Sosa MS; Bernstein E; Aguirre-Ghiso JA
    Cell Rep; 2023 Jun; 42(6):112560. PubMed ID: 37267946
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Exploring the anti-cancer potential of dietary phytochemicals for the patients with breast cancer: A comprehensive review.
    Sohel M; Aktar S; Biswas P; Amin MA; Hossain MA; Ahmed N; Mim MIH; Islam F; Mamun AA
    Cancer Med; 2023 Jul; 12(13):14556-14583. PubMed ID: 37132286
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The targeted next-generation sequence revealed smad4, AKT1, and TP53 mutations from circulating cell-free DNA of breast cancer and its effect on protein structure - A computational approach.
    Balasundaram A; Kumar S U; D TK; Anil Dedge A; R G; K SS; R S; C GPD
    J Biomol Struct Dyn; 2023; 41(24):15584-15597. PubMed ID: 37011004
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. PRMT5 methylating smad4 activates TGF-β signaling and promotes colorectal cancer metastasis.
    Liu A; Yu C; Qiu C; Wu Q; Huang C; Li X; She X; Wan K; Liu L; Li M; Wang Z; Chen Y; Hu F; Song D; Li K; Zhao C; Deng H; Sun X; Xu F; Lai S; Luo X; Hu J; Wang G
    Oncogene; 2023 May; 42(19):1572-1584. PubMed ID: 36991117
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Aberrant promoter hypermethylation of miR-335 and miR-145 is involved in breast cancer PD-L1 overexpression.
    Hajibabaei S; Sotoodehnejadnematalahi F; Nafissi N; Zeinali S; Azizi M
    Sci Rep; 2023 Jan; 13(1):1003. PubMed ID: 36653507
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Redistribution of the SWI/SNF Complex Dictates Coordinated Transcriptional Control over Epithelial-Mesenchymal Transition of Normal breast Cells through TGF-β Signaling.
    Jdeed S; Lengyel M; Uray IP
    Cells; 2022 Aug; 11(17):. PubMed ID: 36078038
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features.
    Hou R; Grimm LJ; Mazurowski MA; Marks JR; King LM; Maley CC; Lynch T; van Oirsouw M; Rogers K; Stone N; Wallis M; Teuwen J; Wesseling J; Hwang ES; Lo JY
    Radiology; 2022 Apr; 303(1):54-62. PubMed ID: 34981975
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. 30 year experience of index case identification and outcomes of cascade testing in high-risk breast and colorectal cancer predisposition genes.
    Woodward ER; Green K; Burghel GJ; Bulman M; Clancy T; Lalloo F; Schlecht H; Wallace AJ; Evans DG
    Eur J Hum Genet; 2022 Apr; 30(4):413-419. PubMed ID: 34866136
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The germline/somatic DNA damage repair gene mutations modulate the therapeutic response in Chinese patients with advanced pancreatic ductal adenocarcinoma.
    Shui L; Li X; Peng Y; Tian J; Li S; He D; Li A; Tian B; Li M; Gao H; An N; Yi C; Cao D
    J Transl Med; 2021 Jul; 19(1):301. PubMed ID: 34247626
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Time Trends in Receipt of Germline Genetic Testing and Results for Women Diagnosed With breast cancer or Ovarian cancer, 2012-2019.
    Kurian AW; Ward KC; Abrahamse P; Bondarenko I; Hamilton AS; Deapen D; Morrow M; Berek JS; Hofer TP; Katz SJ
    J Clin Oncol; 2021 May; 39(15):1631-1640. PubMed ID: 33560870
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The transcription factor c-Jun regulates smad4 expression by upregulating pre-miR-183 expression to promote invasion and metastasis of esophageal squamous cell carcinomas.
    Xu X; Zheng L; Hang N; Zhu G; Mao W; Fan Y; Tao K
    In Vitro Cell Dev Biol Anim; 2020 Aug; 56(7):550-558. PubMed ID: 32886291
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Piperlongumine induces ROS mediated cell death and synergizes paclitaxel in human intestinal cancer cells.
    Rawat L; Hegde H; Hoti SL; Nayak V
    Biomed Pharmacother; 2020 Aug; 128():110243. PubMed ID: 32470748
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. TGFβ regulates NK1R-Tr to affect the proliferation and apoptosis of breast cancer cells.
    Wang L; Wang N; Zhang R; Dong D; Liu R; Zhang L; Ji W; Yu M; Zhang F; Niu R; Zhou Y
    Life Sci; 2020 Sep; 256():117674. PubMed ID: 32380077
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Extracellular Matrix Derived from High Metastatic Human breast cancer Triggers Epithelial-Mesenchymal Transition in Epithelial breast cancer Cells through αvβ3 Integrin.
    M Brandão-Costa R; Helal-Neto E; M Vieira A; Barcellos-de-Souza P; Morgado-Diaz J; Barja-Fidalgo C
    Int J Mol Sci; 2020 Apr; 21(8):. PubMed ID: 32340328
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration.
    Tang X; Li G; Su F; Cai Y; Shi L; Meng Y; Liu Z; Sun J; Wang M; Qian M; Wang Z; Xu X; Cheng YX; Zhu WG; Liu B
    Nucleic Acids Res; 2020 Apr; 48(6):2912-2923. PubMed ID: 31970414
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. BRK phosphorylates smad4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential.
    Miah S; Banks CAS; Ogunbolude Y; Bagu ET; Berg JM; Saraf A; Tettey TT; Hattem G; Dayebgadoh G; Kempf CG; Sardiu M; Napper S; Florens L; Lukong KE; Washburn MP
    Sci Adv; 2019 Oct; 5(10):eaaw3113. PubMed ID: 31681835
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. GDF10 inhibits proliferation and epithelial-mesenchymal transition in triple-negative breast cancer via upregulation of Smad7.
    Zhou T; Yu L; Huang J; Zhao X; Li Y; Hu Y; Lei Y
    Aging (Albany NY); 2019 May; 11(10):3298-3314. PubMed ID: 31147529
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Intravenous administration of cardiac progenitor cell-derived exosomes protects against doxorubicin/trastuzumab-induced cardiac toxicity.
    Milano G; Biemmi V; Lazzarini E; Balbi C; Ciullo A; Bolis S; Ameri P; Di Silvestre D; Mauri P; Barile L; Vassalli G
    Cardiovasc Res; 2020 Feb; 116(2):383-392. PubMed ID: 31098627
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Stimulation of ATF3 interaction with smad4 via TGF-β1 for matrix metalloproteinase 13 gene activation in human breast cancer cells.
    Rohini M; Arumugam B; Vairamani M; Selvamurugan N
    Int J Biol Macromol; 2019 Aug; 134():954-961. PubMed ID: 31082421
    [TBL] [Abstract] [Full Text] [Related]  


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