Terms: = Breast cancer AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS AND Treatment
60 results:
1. p4EBP1 staining predicts outcome in ER-positive endocrine-resistant metastatic breast cancer patients treated with everolimus and exemestane.
Vanacker H; Treilleux I; Schiffler C; Bieche I; Campone M; Patsouris A; Arnedos M; Cottu PH; Jacquin JP; Dalenc F; Pinton A; Servant N; Attignon V; Rouleau E; Morel A; Legrand F; Jimenez M; Andre F; Bachelot T
Br J Cancer; 2024 Mar; 130(4):613-619. PubMed ID: 38182687
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2. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
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3. Extended genetic analysis and tumor characteristics in over 4600 women with suspected hereditary breast and ovarian cancer.
Öfverholm A; Törngren T; Rosén A; Arver B; Einbeigi Z; Haraldsson K; Ståhlbom AK; Kuchinskaya E; Lindblom A; Melin B; Paulsson-Karlsson Y; Stenmark-Askmalm M; Tham E; von Wachenfeldt A; Kvist A; Borg Å; Ehrencrona H
BMC Cancer; 2023 Aug; 23(1):738. PubMed ID: 37563628
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4. ERα/lkb1 complex upregulates E-cadherin expression and stimulates breast cancer growth and progression upon adiponectin exposure.
Naimo GD; Forestiero M; Paolì A; Malivindi R; Gelsomino L; Győrffy B; Leonetti AE; Giordano F; Panza S; Conforti FL; Ruffo P; Panno ML; Mauro L; Andò S
Int J Cancer; 2023 Sep; 153(6):1257-1272. PubMed ID: 37323038
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5. The efficacy of metformin as adjuvant to chemotherapy on IGF levels in non-diabetic female patients with progressive and non-progressive metastatic breast cancer.
Essa NM; Elgendy MO; Gabr A; Mahmoud MM; Alharbi AA; Tashkandi HM; Salem HF; Harakeh S; Boshra MS
Eur Rev Med Pharmacol Sci; 2023 Jun; 27(11):5200-5210. PubMed ID: 37318494
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6. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
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7. Prevalence of Pathogenic Germline Mutations in 13 Hereditary cancer-Related Genes in breast cancer Patients in Narathiwat Province, Thailand.
Sukpan P; Kanokwiroon K; Sriplung H; Laochareonsuk W; Choochuen P; Auseng N; Wanawanakorn K; Sangkhathat S
Asian Pac J Cancer Prev; 2023 Feb; 24(2):525-530. PubMed ID: 36853301
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8. Strong Hereditary Predispositions to Colorectal cancer.
Hryhorowicz S; Kaczmarek-Ryś M; Lis-Tanaś E; Porowski J; Szuman M; Grot N; Kryszczyńska A; Paszkowski J; Banasiewicz T; Pławski A
Genes (Basel); 2022 Dec; 13(12):. PubMed ID: 36553592
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9. MPS1 inhibition primes immunogenicity of KRAS-lkb1 mutant lung cancer.
Kitajima S; Tani T; Springer BF; Campisi M; Osaki T; Haratani K; Chen M; Knelson EH; Mahadevan NR; Ritter J; Yoshida R; Köhler J; Ogino A; Nozawa RS; Sundararaman SK; Thai TC; Homme M; Piel B; Kivlehan S; Obua BN; Purcell C; Yajima M; Barbie TU; Lizotte PH; Jänne PA; Paweletz CP; Gokhale PC; Barbie DA
Cancer Cell; 2022 Oct; 40(10):1128-1144.e8. PubMed ID: 36150391
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10. Midkine noncanonically suppresses AMPK activation through disrupting the lkb1-STRAD-Mo25 complex.
Xia T; Chen D; Liu X; Qi H; Wang W; Chen H; Ling T; Otkur W; Zhang CS; Kim J; Lin SC; Piao HL
Cell Death Dis; 2022 Apr; 13(4):414. PubMed ID: 35487917
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11. Pancreatic cancer with Mutation in BRCA1/2, MLH1, and APC Genes: Phenotype Correlation and Detection of a Novel Germline BRCA2 Mutation.
Vietri MT; D'Elia G; Caliendo G; Albanese L; Signoriello G; Napoli C; Molinari AM
Genes (Basel); 2022 Feb; 13(2):. PubMed ID: 35205366
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12. 30 year experience of index case identification and outcomes of cascade testing in high-risk breast and colorectal cancer predisposition genes.
Woodward ER; Green K; Burghel GJ; Bulman M; Clancy T; Lalloo F; Schlecht H; Wallace AJ; Evans DG
Eur J Hum Genet; 2022 Apr; 30(4):413-419. PubMed ID: 34866136
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13. Biology of primary breast cancer in older women beyond routine biomarkers.
Parks RM; Alfarsi LH; Green AR; Cheung KL
Breast Cancer; 2021 Sep; 28(5):991-1001. PubMed ID: 34165702
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14. New germline mutations in BRCA1, ATM, MUTYH, and RAD51D genes in Tuvans early-onset breast cancer patients.
Gervas P; Molokov A; Ivanova A; Panferova Y; Kiselev A; Chernyshova A; Pisareva L; Choynzonov E; Cherdyntseva N
Exp Oncol; 2021 Mar; 43(1):52-55. PubMed ID: 33785725
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15. Time Trends in Receipt of Germline Genetic Testing and Results for Women Diagnosed With breast cancer or Ovarian cancer, 2012-2019.
Kurian AW; Ward KC; Abrahamse P; Bondarenko I; Hamilton AS; Deapen D; Morrow M; Berek JS; Hofer TP; Katz SJ
J Clin Oncol; 2021 May; 39(15):1631-1640. PubMed ID: 33560870
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16. Pembrolizumab as a monotherapy or in combination with platinum-based chemotherapy in advanced non-small cell lung cancer with PD-L1 tumor proportion score (TPS) ≥50%: real-world data.
Dudnik E; Moskovitz M; Rottenberg Y; Lobachov A; Mandelboim R; Shochat T; Urban D; Wollner M; Nechushtan H; Rotem O; Zer A; Daher S; Bar J;
Oncoimmunology; 2021 Jan; 10(1):1865653. PubMed ID: 33552685
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17. Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carriers of homologous recombination repair genes mutation in response or stable after olaparib treatment.
Fumet JD; Limagne E; Thibaudin M; Truntzer C; Bertaut A; Rederstorff E; Ghiringhelli F
BMC Cancer; 2020 Aug; 20(1):748. PubMed ID: 32778095
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18. Genomic landscape of metastatic breast cancer identifies preferentially dysregulated pathways and targets.
Paul MR; Pan TC; Pant DK; Shih NN; Chen Y; Harvey KL; Solomon A; Lieberman D; Morrissette JJ; Soucier-Ernst D; Goodman NG; Stavropoulos SW; Maxwell KN; Clark C; Belka GK; Feldman M; DeMichele A; Chodosh LA
J Clin Invest; 2020 Aug; 130(8):4252-4265. PubMed ID: 32657779
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19. Genetic Testing and Screening Recommendations for Patients with Hereditary breast cancer.
Bharucha PP; Chiu KE; François FM; Scott JL; Khorjekar GR; Tirada NP
Radiographics; 2020; 40(4):913-936. PubMed ID: 32469631
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20. Klotho rewires cellular metabolism of breast cancer cells through alteration of calcium shuttling and mitochondrial activity.
Shmulevich R; Nissim TB; Wolf I; Merenbakh-Lamin K; Fishman D; Sekler I; Rubinek T
Oncogene; 2020 Jun; 39(24):4636-4649. PubMed ID: 32398866
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