BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Breast cancer AND SYK, P43405, 6850, ENSG00000165025 AND Treatment
22 results:

  • 1. A phase Ib study evaluating the recommended phase II dose, safety, tolerability, and efficacy of mivavotinib in combination with nivolumab in advanced solid tumors.
    Juric D; Barve M; Vaishampayan U; Roda D; Calvo A; Jañez NM; Trigo J; Greystoke A; Harvey RD; Olszanski AJ; Opyrchal M; Spira A; Thistlethwaite F; Jiménez B; Sappal JH; Kannan K; Riley J; Li C; Li C; Gregory RC; Miao H; Wang S
    Cancer Med; 2024 Mar; 13(5):. PubMed ID: 38501219
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Combination of bendamustine-azacitidine against syk target of breast cancer: an
    Muthumanickam S; Ramachandran B; Boomi P; Jeyakanthan J; Prabu HG; Jegatheswaran S; Premkumar K
    J Biomol Struct Dyn; 2023; 41(23):13950-13962. PubMed ID: 37098715
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Tumor cell syk expression modulates the tumor immune microenvironment composition in human cancer via TNF-α dependent signaling.
    Aguirre-Ducler A; Gianino N; Villarroel-Espindola F; Desai S; Tang D; Zhao H; Syrigos K; Trepicchio WL; Kannan K; Gregory RC; Schalper KA
    J Immunother Cancer; 2022 Jul; 10(7):. PubMed ID: 35868661
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. American Joint Committee on cancer Tumor Staging System Predicts the Outcome and Metastasis Pattern in Conjunctival Melanoma.
    Jia S; Zhu T; Shi H; Zong C; Bao Y; Wen X; Ge S; Ruan J; Xu S; Jia R; Fan X
    Ophthalmology; 2022 Jul; 129(7):771-780. PubMed ID: 35245602
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. DOCK2 regulates antifungal immunity by regulating RAC GTPase activity.
    Ma X; Tan X; Yu B; Sun W; Wang H; Hu H; Du Y; He R; Gao R; Peng Q; Cui Z; Pan T; Feng X; Wang J; Xu C; Zhu B; Liu W; Wang C
    Cell Mol Immunol; 2022 May; 19(5):602-618. PubMed ID: 35079145
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A nomogram to predict the high-risk RS in HR+/HER2-breast cancer patients older than 50 years of age.
    Yu J; Wu J; Huang O; He J; Zhu L; Chen W; Li Y; Chen X; Shen K
    J Transl Med; 2021 Feb; 19(1):75. PubMed ID: 33593381
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer.
    Zhao ZM; Yost SE; Hutchinson KE; Li SM; Yuan YC; Noorbakhsh J; Liu Z; Warden C; Johnson RM; Wu X; Chuang JH; Yuan Y
    BMC Cancer; 2019 Jan; 19(1):96. PubMed ID: 30665374
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Identification of key genes and pathways associated with classical Hodgkin lymphoma by bioinformatics analysis.
    Kuang Z; Guo L; Li X
    Mol Med Rep; 2017 Oct; 16(4):4685-4693. PubMed ID: 28791394
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. DNA methylation and breast tumor clinicopathological features: The Western New York Exposures and breast cancer (WEB) study.
    Callahan CL; Wang Y; Marian C; Weng DY; Eng KH; Tao MH; Ambrosone CB; Nie J; Trevisan M; Smiraglia D; Edge SB; Shields PG; Freudenheim JL
    Epigenetics; 2016 Sep; 11(9):643-652. PubMed ID: 27245195
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Identification of Personalized Chemoresistance Genes in Subtypes of Basal-Like breast cancer Based on Functional Differences Using Pathway Analysis.
    Wu T; Wang X; Li J; Song X; Wang Y; Wang Y; Zhang L; Li Z; Tian J
    PLoS One; 2015; 10(6):e0131183. PubMed ID: 26126114
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Targeting a cell state common to triple-negative breast cancers.
    Muellner MK; Mair B; Ibrahim Y; Kerzendorfer C; Lechtermann H; Trefzer C; Klepsch F; Müller AC; Leitner E; Macho-Maschler S; Superti-Furga G; Bennett KL; Baselga J; Rix U; Kubicek S; Colinge J; Serra V; Nijman SM
    Mol Syst Biol; 2015 Feb; 11(1):789. PubMed ID: 25699542
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Modulation by syk of Bcl-2, calcium and the calpain-calpastatin proteolytic system in human breast cancer cells.
    Fei B; Yu S; Geahlen RL
    Biochim Biophys Acta; 2013 Oct; 1833(10):2153-64. PubMed ID: 23684705
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Reactivation of syk gene by AZA suppresses metastasis but not proliferation of breast cancer cells.
    Xia TS; Shi JP; Ding Q; Liu XA; Zhao Y; Liu YX; Xia JG; Wang S; Ding YB
    Med Oncol; 2012 Jun; 29(2):448-53. PubMed ID: 21347717
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The protein-tyrosine kinase syk interacts with TRAF-interacting protein TRIP in breast epithelial cells.
    Zhou Q; Geahlen RL
    Oncogene; 2009 Mar; 28(10):1348-56. PubMed ID: 19151749
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The ERBB3 receptor in cancer and cancer gene therapy.
    Sithanandam G; Anderson LM
    Cancer Gene Ther; 2008 Jul; 15(7):413-48. PubMed ID: 18404164
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Hypoxia regulates cross-talk between syk and Lck leading to breast cancer progression and angiogenesis.
    Chakraborty G; Rangaswami H; Jain S; Kundu GC
    J Biol Chem; 2006 Apr; 281(16):11322-31. PubMed ID: 16474166
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cells.
    Lu J; Lin WH; Chen SY; Longnecker R; Tsai SC; Chen CL; Tsai CH
    J Biol Chem; 2006 Mar; 281(13):8806-14. PubMed ID: 16431925
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Reactivation of syk expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness.
    Yuan Y; Liu H; Sahin A; Dai JL
    Int J Cancer; 2005 Feb; 113(4):654-9. PubMed ID: 15455373
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. syk, a protein-tyrosine kinase, suppresses the cell motility and nuclear factor kappa B-mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3'-kinase activity in breast cancer cells.
    Mahabeleshwar GH; Kundu GC
    J Biol Chem; 2003 Feb; 278(8):6209-21. PubMed ID: 12477728
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Structure-based design of novel anticancer agents.
    Uckun FM; Sudbeck EA; Mao C; Ghosh S; Liu XP; Vassilev AO; Navara CS; Narla RK
    Curr Cancer Drug Targets; 2001 May; 1(1):59-71. PubMed ID: 12188892
    [TBL] [Abstract] [Full Text] [Related]  


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